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Gene : CkIIbeta D. melanogaster

DB identifier  ? FBgn0000259 Secondary Identifier  ? CG15224
Name  ? Casein kinase II beta subunit Source  FlyBase
  • synonyms:
  • CKIIb,
  • FBgn0000259,
  • DmCK2beta,
  • dCKII beta,
  • And,
  • CK-IIbeta,
  • CK-2,
  • CCK2,
  • CKIIbeta,
  • mushroom bodies undersized,
  • casein kinase 2,
  • Casein kinase II,
  • Casein kinase II beta subunit,
  • CkIIbeta1,
  • casein kinase II beta,
  • casein kinase 2 regulatory subunit,
  • Cask-II-b,
  • dCK2beta,
  • CKII-beta1,
  • CKII beta,
  • CK-II beta,
  • Ds cas kin,
  • CK2beta,
  • mbu,
  • CK2-beta,
  • DmCKIIbeta,
  • FBan0015224,
  • CK2,
  • betaCK2,
  • CG15224,
  • CkII-beta,
  • FBgn0027953,
  • Andante,
  • KC2B_DROME,
  • CK2 (beta subunit),
  • dCKII,
  • CK II,
  • CKII

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42 Alleles

DB identifier Symbol Allele Class Organism
FBal0281638 CkIIbeta[HMS02636]   Drosophila melanogaster
FBal0245487 CkIIbeta[JF01195]   Drosophila melanogaster
FBal0148100 CkIIbeta[mbuDeltaA6-1]   Drosophila melanogaster
FBal0156780 CkIIbeta[BG02223]   Drosophila melanogaster
FBal0131296 CkIIbeta[mbuP1] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0192637 CkIIbeta[EY21591]   Drosophila melanogaster
FBal0264186 CkIIbeta[Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0264187 CkIIbeta[dsRNA.cJa.Scer\UAS]   Drosophila melanogaster
FBal0277599 CkIIbeta[MI06990]   Drosophila melanogaster
FBal0184332 CkIIbeta[dsRNA.cIb]   Drosophila melanogaster
FBal0145125 CkIIbeta[gDNA]   Drosophila melanogaster
FBal0141855 CkIIbeta[dsRNA.cIa]   Drosophila melanogaster
FBal0148101 CkIIbeta[mbuDeltaA20-1L]   Drosophila melanogaster
FBal0145124 CkIIbeta[mbuDeltaA26-2L] loss of function allele Drosophila melanogaster
FBal0003276 CkIIbeta[And] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0262771 CkIIbeta[GL00303]   Drosophila melanogaster
FBal0263082 CkIIbeta[HMS00058]   Drosophila melanogaster
FBal0145130 CkIIbeta[C109.114S.Scer\UAS]   Drosophila melanogaster
FBal0145129 CkIIbeta[C137.140S.Scer\UAS]   Drosophila melanogaster
FBal0145128 CkIIbeta[Ie-VIIa.Scer\UAS]   Drosophila melanogaster
FBal0145127 CkIIbeta[R47C.Scer\UAS]   Drosophila melanogaster
FBal0145126 CkIIbeta[S2.3.4A.Scer\UAS]   Drosophila melanogaster
FBal0286933 CkIIbeta[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286934 CkIIbeta[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0194269 CkIIbeta[mbuDeltaA]   Drosophila melanogaster
FBal0194270 CkIIbeta[GT1.Delta6]   Drosophila melanogaster
FBal0194271 CkIIbeta[GT1.Delta8]   Drosophila melanogaster
FBal0194272 CkIIbeta[VIIb.Scer\UAS]   Drosophila melanogaster
FBal0194273 CkIIbeta[VIIc.Scer\UAS]   Drosophila melanogaster
FBal0194274 CkIIbeta[VIId.Scer\UAS]   Drosophila melanogaster

141 Clones

Secondary Identifier DB identifier
AT31207 FBcl0008551
bs09g07 FBcl0047049
bs78a12 FBcl0048057
EC14958 FBcl0062381
EP16814 FBcl0074821
EP09511 FBcl0074829
EP02227 FBcl0075009
EN13255 FBcl0092439
EN09306 FBcl0092441
EN16851 FBcl0092445
GH28737 FBcl0115843
GH18688 FBcl0117061
EK148602 FBcl0128456
EK012601 FBcl0128504
EK291315 FBcl0128526
EK051702 FBcl0128530
EK244147 FBcl0129266
EK067554 FBcl0129278
EK119017 FBcl0129290
EK108905 FBcl0129386
EK198413 FBcl0129458
EK068542 FBcl0129470
EK140543 FBcl0129548
EK273402 FBcl0129596
EK068414 FBcl0129618
EK173732 FBcl0129650
EK079809 FBcl0129686
EK026760 FBcl0129690
EK085113 FBcl0129696
EK087409 FBcl0129702

19 Exons

DB identifier Symbol
FBgn0000259:1 CkIIbeta:1
FBgn0000259:8 CkIIbeta:8
FBgn0000259:9 CkIIbeta:9
FBgn0000259:10 CkIIbeta:10
FBgn0000259:11 CkIIbeta:11
FBgn0000259:12 CkIIbeta:12
FBgn0000259:16 CkIIbeta:16
FBgn0000259:7 CkIIbeta:7
FBgn0000259:18 CkIIbeta:18
FBgn0000259:3 CkIIbeta:3
FBgn0000259:14 CkIIbeta:14
FBgn0000259:2 CkIIbeta:2
FBgn0000259:15 CkIIbeta:15
FBgn0000259:19 CkIIbeta:19
FBgn0000259:6 CkIIbeta:6
FBgn0000259:13 CkIIbeta:13
FBgn0000259:4 CkIIbeta:4
FBgn0000259:5 CkIIbeta:5
FBgn0000259:17 CkIIbeta:17

10 Transcripts

DB identifier Gene
FBtr0308085 CkIIbeta
FBtr0308084 CkIIbeta
FBtr0073558 CkIIbeta
FBtr0333204 CkIIbeta
FBtr0299569 CkIIbeta
FBtr0073561 CkIIbeta
FBtr0073560 CkIIbeta
FBtr0100540 CkIIbeta
FBtr0307896 CkIIbeta
FBtr0073562 CkIIbeta

20 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0073558-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0073562-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0100540-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0073560-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0073561-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299569-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333204-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307896-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0308084-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0308085-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073558-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073562-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0100540-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073560-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073561-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299569-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333204-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0307896-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0308084-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0308085-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
32132 NCBI Entrez Gene identifiers FBgn0000259
58538 BioGRID FBgn0000259

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2340.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2508.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1780.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1318.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1660.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2864.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1584.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1603.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1501.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2082.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2677.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1978.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1742.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1080.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2967.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2317.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2527.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1864.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1969.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2313.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1385.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3085.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1741.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2642.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1995.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 5369.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1823.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2198.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2359.0
FBgn0000259 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2300.0

18 Introns

DB identifier
Organism . Name
intron_FBgn0000259:3_FBgn0000259:8 Drosophila melanogaster
intron_FBgn0000259:8_FBgn0000259:9 Drosophila melanogaster
intron_FBgn0000259:9_FBgn0000259:10 Drosophila melanogaster
intron_FBgn0000259:10_FBgn0000259:11 Drosophila melanogaster
intron_FBgn0000259:11_FBgn0000259:12 Drosophila melanogaster
intron_FBgn0000259:12_FBgn0000259:14 Drosophila melanogaster
intron_FBgn0000259:1_FBgn0000259:8 Drosophila melanogaster
intron_FBgn0000259:12_FBgn0000259:16 Drosophila melanogaster
intron_FBgn0000259:7_FBgn0000259:8 Drosophila melanogaster
intron_FBgn0000259:12_FBgn0000259:18 Drosophila melanogaster
intron_FBgn0000259:2_FBgn0000259:8 Drosophila melanogaster
intron_FBgn0000259:12_FBgn0000259:15 Drosophila melanogaster
intron_FBgn0000259:12_FBgn0000259:19 Drosophila melanogaster
intron_FBgn0000259:6_FBgn0000259:8 Drosophila melanogaster
intron_FBgn0000259:12_FBgn0000259:13 Drosophila melanogaster
intron_FBgn0000259:4_FBgn0000259:8 Drosophila melanogaster
intron_FBgn0000259:5_FBgn0000259:8 Drosophila melanogaster
intron_FBgn0000259:12_FBgn0000259:17 Drosophila melanogaster

40 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage CkIIbeta none -3.564606068   19067489
Lipid storage CkIIbeta none -1.403933178   19067489
Lipid storage CkIIbeta none -1.678232324   19067489
Chlamydia caviae infection CkIIbeta Decreased Chlamydia caviae infection np   17967059
Cell cycle regulation (2) CkIIbeta none np   15616552
Intracellular Listeria monocytogenes infection CkIIbeta Punctate GFP protein expression (GFP spots) moderate   16020693
Cell size and cell-cycle regulation (1) CkIIbeta none sp   16496002
Cell size and cell-cycle regulation (1) CkIIbeta Decreased G2 DNA content sp   16496002
Cell size and cell-cycle regulation (1) CkIIbeta none sp   16496002
Cell size and cell-cycle regulation (1) CkIIbeta none sp   16496002
Cell size and cell-cycle regulation (1) CkIIbeta none sp   16496002
Cell size and cell-cycle regulation (2) CkIIbeta none 1.355   16496002
Cell size and cell-cycle regulation (3) CkIIbeta none 457   16496002
Embryonic nervous system development CkIIbeta Defects in commissures and longitudinal connectives of ventral nerve cord, disorganized peripheral nervous system neurons np   15534205
Muscle morphogenesis and function (1) CkIIbeta Lethal np   20220848
Muscle morphogenesis and function (1) CkIIbeta Lethal np   20220848
Muscle morphogenesis and function (2) CkIIbeta Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) CkIIbeta Developmentally lethal 0   21074052
Heart development and function (1) CkIIbeta none 1   20371351
Heart development and function (1) CkIIbeta none 1   20371351
Serratia marcescens infection (1) CkIIbeta none 0.583333333333333   19520911
Notch pathway regulation (4) CkIIbeta Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) CkIIbeta Completely lethal (pupal) sp   19363474
Self-renewal and differentiation in neural stem cells CkIIbeta GFP aggregates number, GFP aggregates size, neuroblast less large cells, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with unchanged neuroblast cell size, neuroblast underproliferation, lethal sp   21549331
Self-renewal and differentiation in neural stem cells CkIIbeta GFP aggregates number, GFP aggregates size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast loss, neuroblast loss with unchanged neuroblast cell size, neuroblast underprolif sp   21549331
Pol II elongation CkIIbeta Decreased Hsp70 mRNA expression 54 20 min heat shock 19279664
Notch pathway regulation (1) CkIIbeta Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) CkIIbeta none np en-GAL4 20493818
Notch pathway regulation (3) CkIIbeta none np   20493818
Adiposity regulation (1) CkIIbeta none -0.107   20074523

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