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Gene : PyK D. melanogaster

DB identifier  ? FBgn0003178 Secondary Identifier  ? CG7070
Name  ? Pyruvate kinase Source  FlyBase
  • synonyms:
  • PYK,
  • Pyruvate Kinase,
  • CG7070,
  • FBgn0003178,
  • FBan0007070

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15 Alleles

DB identifier Symbol Allele Class Organism
FBal0182064 PyK[DG05605]   Drosophila melanogaster
FBal0211943 PyK[CB04247]   Drosophila melanogaster
FBal0182061 PyK[d08895]   Drosophila melanogaster
FBal0156011 PyK[Wee-P338]   Drosophila melanogaster
FBal0182062 PyK[d05959]   Drosophila melanogaster
FBal0182063 PyK[d05514]   Drosophila melanogaster
FBal0182060 PyK[f06019]   Drosophila melanogaster
FBal0159952 PyK[EY10213]   Drosophila melanogaster
FBal0262583 PyK[GL00099]   Drosophila melanogaster
FBal0243850 PyK[NIG.7070R]   Drosophila melanogaster
FBal0208188 PyK[GD12123]   Drosophila melanogaster
FBal0208189 PyK[GD16178]   Drosophila melanogaster
FBal0228698 PyK[NP2224]   Drosophila melanogaster
FBal0228699 PyK[NP2635]   Drosophila melanogaster
FBal0228700 PyK[d08171]   Drosophila melanogaster

480 Clones

Secondary Identifier DB identifier
RH69643 FBcl0322382
RH17851 FBcl0322383
LD01517 FBcl0322384
DPiM_SD06874 FBcl0741770
UUGC1064 FBcl0005695
AT16517 FBcl0032791
EK136712 FBcl0069990
EK288759 FBcl0070482
EK249164 FBcl0070752
EK195255 FBcl0070806
EK039039 FBcl0072258
EK062827 FBcl0072404
EK204408 FBcl0072416
EK263410 FBcl0072662
EK251263 FBcl0074620
EK274326 FBcl0074640
EK308235 FBcl0074698
EK045124 FBcl0074938
EK212448 FBcl0075640
EK187528 FBcl0076048
EN08222 FBcl0098991
EN14325 FBcl0098999
EN08452 FBcl0099033
EN04231 FBcl0099039
GH14451 FBcl0117617
GH09172 FBcl0118713
GH14417 FBcl0118745
GH17921 FBcl0118911
GH09144 FBcl0118937
GH22969 FBcl0118995

5 Exons

DB identifier Symbol
FBgn0003178:1 PyK:1
FBgn0003178:3 PyK:3
FBgn0003178:4 PyK:4
FBgn0003178:5 PyK:5
FBgn0003178:2 PyK:2

2 Transcripts

DB identifier Gene
FBtr0084213 PyK
FBtr0084214 PyK

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0084213-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0084214-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0084213-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0084214-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42620 NCBI Entrez Gene identifiers FBgn0003178
67578 BioGRID FBgn0003178

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 4065.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 4064.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2441.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 7527.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 3191.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 3915.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 6391.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 4393.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 5211.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2539.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 4716.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2931.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 3151.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2486.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 5280.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 4245.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 5533.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 4151.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 3013.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 4872.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 5530.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 4134.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2977.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 4208.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2611.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 8086.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1305.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 210.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 161.0
FBgn0003178 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 201.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0003178:1_FBgn0003178:3 Drosophila melanogaster
intron_FBgn0003178:3_FBgn0003178:4 Drosophila melanogaster
intron_FBgn0003178:4_FBgn0003178:5 Drosophila melanogaster
intron_FBgn0003178:2_FBgn0003178:3 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage PyK none -2.590665164   19067489
Lipid storage PyK none -1.553988184   19067489
Cell size and cell-cycle regulation (1) PyK none sp   16496002
Cell size and cell-cycle regulation (1) PyK none sp   16496002
Muscle morphogenesis and function (1) PyK Lethal np   20220848
Muscle morphogenesis and function (3) PyK none np   20220848
Heat nociception (1) PyK none -1.17   21074052
Heart development and function (1) PyK none 1   20371351
Serratia marcescens infection (1) PyK none -0.543478260869565   19520911
Serratia marcescens infection (1) PyK none 0.578947368421052   19520911
Notch pathway regulation (4) PyK Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) PyK none 0   19363474
Notch pathway regulation (1) PyK Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) PyK Lethal strong en-GAL4 20493818
Notch pathway regulation (2) PyK none np C96-GAL4 20493818
Notch pathway regulation (2) PyK Upregulation of Notch pathway; wing disc NRE:EGFP: up; wing disc myrRFP: accumulation, reduced; lethal sp en-GAL4 20493818
Notch pathway regulation (2) PyK Upregulation of Notch pathway; wing disc size: overgrown; wing disc NRE:EGFP: up; wing disc myrRFP: accumulation, reduced; lethal sp en-GAL4 20493818
Notch pathway regulation (2) PyK Upregulation of Notch pathway; wing disc size: overgrown; wing disc NRE:EGFP: up; wing disc myrRFP: accumulation, reduced; lethal sp en-GAL4 20493818
Notch pathway regulation (2) PyK Wing disc NRE:EGFP: up, gap; wing disc myrRFP: accumulation sp en-GAL4 20493818
Notch pathway regulation (3) PyK Only lethal with Notch np   20493818
Adiposity regulation (1) PyK none -0.203   20074523
Vaccinia virus infection PyK none sp   20585561
Hippo pathway regulation PyK none 1.16   23263283
Glycosylation regulation (1) PyK Increased alpha1,6-fucose Chp glycosylation sp   21203496
Glycosylation regulation (2) PyK none np   21203496
Huntingtin (Htt) aggregates formation PyK Decreased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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