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Gene : eff D. melanogaster

DB identifier  ? FBgn0011217 Secondary Identifier  ? CG7425
Name  ? effete Source  FlyBase
  • synonyms:
  • ms(3)ry3,
  • mei68,
  • CG7425,
  • EFF,
  • UBCD-1,
  • anon-WO0118547.343,
  • ms(3)88D,
  • UBC4,
  • FBgn0011333,
  • FBgn0062081,
  • l(3)s1782,
  • 6535,
  • Ubiquitin conjugating enzyme 1,
  • SS3-3,
  • l(3)01462,
  • FBgn0013663,
  • effette,
  • FBgn0011011,
  • E(Pc)88D,
  • FBgn0011657,
  • UbcD,
  • Effete,
  • FBgn0004831,
  • ms(3)3,
  • 3527,
  • UBCD1,
  • meiotic 68,
  • ms(3)1,
  • FBgn0013935,
  • FBgn0011217,
  • Suppressor of GMR-sina 3-3,
  • l(3)j2C8,
  • FBan0007425,
  • ms(3)ry1,
  • fs(3)01295,
  • Ubc-D1,
  • ms(3)neo2,
  • FBgn0013661,
  • ms(3)01295

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73 Alleles

DB identifier Symbol Allele Class Organism
FBal0211778 eff[CC01915]   Drosophila melanogaster
FBal0180020 eff[DG04302]   Drosophila melanogaster
FBal0180014 eff[d10589]   Drosophila melanogaster
FBal0180015 eff[d08220]   Drosophila melanogaster
FBal0180016 eff[d03427]   Drosophila melanogaster
FBal0276899 eff[G15069]   Drosophila melanogaster
FBal0180017 eff[d00904]   Drosophila melanogaster
FBal0180012 eff[e03661]   Drosophila melanogaster
FBal0180013 eff[e01950]   Drosophila melanogaster
FBal0180019 eff[c04358]   Drosophila melanogaster
FBal0180018 eff[c04398]   Drosophila melanogaster
FBal0159265 eff[EY01601]   Drosophila melanogaster
FBal0028178 eff[10]   Drosophila melanogaster
FBal0028179 eff[11]   Drosophila melanogaster
FBal0028180 eff[12]   Drosophila melanogaster
FBal0028181 eff[13]   Drosophila melanogaster
FBal0028174 eff[6]   Drosophila melanogaster
FBal0028175 eff[7]   Drosophila melanogaster
FBal0028176 eff[8]   Drosophila melanogaster
FBal0028177 eff[9]   Drosophila melanogaster
FBal0151995 eff[L89F]   Drosophila melanogaster
FBal0151996 eff[L88D]   Drosophila melanogaster
FBal0060432 eff[tre2]   Drosophila melanogaster
FBal0060433 eff[tre1]   Drosophila melanogaster
FBal0003508 eff[3]   Drosophila melanogaster
FBal0003519 eff[01462]   Drosophila melanogaster
FBal0003506 eff[1]   Drosophila melanogaster
FBal0003507 eff[2]   Drosophila melanogaster
FBal0003509 eff[4]   Drosophila melanogaster
FBal0003510 eff[5]   Drosophila melanogaster

207 Clones

Secondary Identifier DB identifier
AT31676 FBcl0041789
EK229528 FBcl0055414
EK151302 FBcl0055694
EK260857 FBcl0055700
EK192215 FBcl0055714
EK180109 FBcl0055736
EK120210 FBcl0055762
EK073040 FBcl0055768
EK211106 FBcl0055774
EK190120 FBcl0055778
EK063123 FBcl0055800
EK184929 FBcl0055816
EK114410 FBcl0055820
EK048723 FBcl0055846
EK063524 FBcl0055858
EK200126 FBcl0055862
EK014924 FBcl0055882
EK155528 FBcl0055888
bs28h07 FBcl0057527
bs35e05 FBcl0057529
bs44h05 FBcl0057531
bs83d11 FBcl0057533
bs36a10 FBcl0057535
bs71e03 FBcl0057539
bs55h03 FBcl0057543
EC34228 FBcl0072671
EC25989 FBcl0072673
EN09319 FBcl0101447
EN02722 FBcl0101455
EN13748 FBcl0101457

8 Exons

DB identifier Symbol
FBgn0011217:6 eff:6
FBgn0011217:5 eff:5
FBgn0011217:4 eff:4
FBgn0011217:3 eff:3
FBgn0011217:1 eff:1
FBgn0011217:8 eff:8
FBgn0011217:7 eff:7
FBgn0011217:2 eff:2

3 Transcripts

DB identifier Gene
FBtr0310554 eff
FBtr0336876 eff
FBtr0083018 eff

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0083018-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0310554-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0336876-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083018-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0310554-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0336876-3-prime-utr Drosophila melanogaster

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80 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
41785 NCBI Entrez Gene identifiers FBgn0011217
66859 BioGRID FBgn0011217

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 7610.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 5859.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 4393.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 4486.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 5232.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 7645.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 6786.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3705.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2873.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 7108.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 5931.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 3024.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 6440.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 5605.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 7762.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 4048.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 5242.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 4182.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 6138.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 5629.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 5539.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 6353.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 5018.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 5112.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 4858.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 8958.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 8118.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 6065.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 5827.0
FBgn0011217 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 6021.0

7 Introns

DB identifier
Organism . Name
intron_FBgn0011217:8_FBgn0011217:7 Drosophila melanogaster
intron_FBgn0011217:7_FBgn0011217:5 Drosophila melanogaster
intron_FBgn0011217:5_FBgn0011217:4 Drosophila melanogaster
intron_FBgn0011217:4_FBgn0011217:3 Drosophila melanogaster
intron_FBgn0011217:3_FBgn0011217:2 Drosophila melanogaster
intron_FBgn0011217:6_FBgn0011217:5 Drosophila melanogaster
intron_FBgn0011217:3_FBgn0011217:1 Drosophila melanogaster

30 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage eff none -0.339225293   19067489
Lipid storage eff none 1.86430298   19067489
Imd pathway regulation eff Increased Dipt::lacZ protein expression after lipopolysaccharide stimulation 24   15221030
Hedgehog signaling eff Decreased Hedgehog reporter activity -2.79   16311596
Constitutive protein secretion and Golgi organization (1) eff Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) eff none sp   16496002
Cell size and cell-cycle regulation (1) eff none sp   16496002
Lipid storage eff Fewer lipid droplets strong   18408709
Muscle morphogenesis and function (1) eff Lethal np   20220848
Muscle morphogenesis and function (1) eff Lethal np   20220848
Muscle morphogenesis and function (2) eff Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) eff Developmentally lethal 0   21074052
Heat nociception (1) eff Developmentally lethal -1.17   21074052
Heart development and function (1) eff none 1   20371351
Heart development and function (2) eff Decreased viability 7.27   20371351
Serratia marcescens infection (1) eff none 1.01408450704225   19520911
Notch pathway regulation (4) eff Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) eff Completely lethal (pupal) sp   19363474
Akt-TOR pathway negative feedback regulation eff Decreased dAkt phosphorylation after insulin stimulation -2.8 10 min insulin stimulation 20585550
Hh pathway regulation eff Downregulation of Hh pathway -0.324781103941061   17903264
Hh pathway regulation eff Downregulation of Hh pathway -0.261023598276345   17903264
Self-renewal and differentiation in neural stem cells eff GFP aggregates number, GFP aggregates size, ganglion mother cell shorter lineages, neuroblast underproliferation, lethal sp   21549331
Notch pathway regulation (1) eff Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) eff Delay of larval development; lethal sp en-GAL4 20493818
Notch pathway regulation (2) eff none np C96-GAL4 20493818
Notch pathway regulation (2) eff none np en-GAL4 20493818
Notch pathway regulation (3) eff Upregulation of Notch pathway np   20493818
Hippo pathway regulation eff none -1.07   23263283
Srp/Lz-induced transcriptional activation eff Decreased Srp/Lz-induced transcription -4.62   20368357
Glycosylation regulation (1) eff none sp   21203496

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