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Gene : eRF1 D. melanogaster

DB identifier  ? FBgn0036974 Secondary Identifier  ? CG5605
Name  ? eukaryotic release factor 1 Source  FlyBase
  • synonyms:
  • CG5605,
  • FBgn0011462,
  • FBgn0036974,
  • Dm0184,
  • FBan0005605,
  • l(3)neo28,
  • Eukaryotic release factor 1,
  • eRF1,
  • Group J,
  • FBgn0010710,
  • l(3)05637,
  • l(3)00103,
  • l(3)77ABb

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31 Alleles

DB identifier Symbol Allele Class Organism
FBal0211777 eRF1[CB03931]   Drosophila melanogaster
FBal0285968 eRF1[YB0271]   Drosophila melanogaster
FBal0180038 eRF1[d01190]   Drosophila melanogaster
FBal0130394 eRF1[EP3195]   Drosophila melanogaster
FBal0011042 eRF1[neo28]   Drosophila melanogaster
FBal0009369 eRF1[00103]   Drosophila melanogaster
FBal0119191 eRF1[EP3121]   Drosophila melanogaster
FBal0043817 eRF1[05637]   Drosophila melanogaster
FBal0043818 eRF1[10470]   Drosophila melanogaster
FBal0121702 eRF1[01850]   Drosophila melanogaster
FBal0102530 eRF1[A7]   Drosophila melanogaster
FBal0180041 eRF1[2604]   Drosophila melanogaster
FBal0180040 eRF1[2633]   Drosophila melanogaster
FBal0147180 eRF1[KY7] amorphic allele - genetic evidence Drosophila melanogaster
FBal0102526 eRF1[F2]   Drosophila melanogaster
FBal0102525 eRF1[K3]   Drosophila melanogaster
FBal0152011 eRF1[unspecified]   Drosophila melanogaster
FBal0102527 eRF1[D1]   Drosophila melanogaster
FBal0180039 eRF1[709]   Drosophila melanogaster
FBal0102524 eRF1[K7]   Drosophila melanogaster
FBal0102523 eRF1[M1]   Drosophila melanogaster
FBal0102521 eRF1[V2]   Drosophila melanogaster
FBal0102529 eRF1[C1]   Drosophila melanogaster
FBal0102528 eRF1[C2]   Drosophila melanogaster
FBal0102522 eRF1[U3]   Drosophila melanogaster
FBal0209485 eRF1[GD4704]   Drosophila melanogaster
FBal0215548 eRF1[22b]   Drosophila melanogaster
FBal0219357 eRF1[DG10404]   Drosophila melanogaster
FBal0288062 eRF1[C474.1]   Drosophila melanogaster
FBal0222490 eRF1[c01336]   Drosophila melanogaster

469 Clones

Secondary Identifier DB identifier
ESG0113a.B21_D10 FBcl0002047
CK00468 FBcl0060247
EC22223 FBcl0069867
EC14204 FBcl0069901
EC00717 FBcl0069909
EC00317 FBcl0070309
EP12660 FBcl0085599
EP15863 FBcl0085613
EP05645 FBcl0085617
GH13909 FBcl0128859
GH13681 FBcl0128913
GH13669 FBcl0128949
GH22077 FBcl0128975
GH18908 FBcl0128979
EK216029 FBcl0135132
EK303541 FBcl0136068
EK168951 FBcl0136072
EK084946 FBcl0136134
EK113602 FBcl0136144
EK172562 FBcl0136152
EK103063 FBcl0136158
EK186715 FBcl0136196
EK122941 FBcl0136206
EK042259 FBcl0136212
EK142355 FBcl0136224
EK077446 FBcl0136234
EK178008 FBcl0136244
EK228712 FBcl0136278
GM16046 FBcl0147247
GM12574 FBcl0147251

15 Exons

DB identifier Symbol
FBgn0036974:1 eRF1:1
FBgn0036974:7 eRF1:7
FBgn0036974:8 eRF1:8
FBgn0036974:9 eRF1:9
FBgn0036974:10 eRF1:10
FBgn0036974:11 eRF1:11
FBgn0036974:12 eRF1:12
FBgn0036974:14 eRF1:14
FBgn0036974:3 eRF1:3
FBgn0036974:5 eRF1:5
FBgn0036974:2 eRF1:2
FBgn0036974:6 eRF1:6
FBgn0036974:4 eRF1:4
FBgn0036974:13 eRF1:13
FBgn0036974:15 eRF1:15

8 Transcripts

DB identifier Gene
FBtr0331818 eRF1
FBtr0331817 eRF1
FBtr0078173 eRF1
FBtr0078178 eRF1
FBtr0078174 eRF1
FBtr0078175 eRF1
FBtr0078176 eRF1
FBtr0078177 eRF1

16 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0078173-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0078174-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0078175-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0078176-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0078177-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0078178-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0331817-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0331818-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078173-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078174-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078175-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078176-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078177-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078178-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0331817-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0331818-3-prime-utr Drosophila melanogaster

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46 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40240 NCBI Entrez Gene identifiers FBgn0036974
65501 BioGRID FBgn0036974

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 6725.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 6938.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2242.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 3771.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 3519.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 3690.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 4585.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2630.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1816.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3289.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 4082.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2250.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 4005.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 3093.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 3484.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 4052.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3033.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 3206.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 8159.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 3151.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 4378.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 6177.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 3015.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2242.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 3740.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6133.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 4314.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2609.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2315.0
FBgn0036974 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 3129.0

14 Introns

DB identifier
Organism . Name
intron_FBgn0036974:1_FBgn0036974:7 Drosophila melanogaster
intron_FBgn0036974:7_FBgn0036974:8 Drosophila melanogaster
intron_FBgn0036974:8_FBgn0036974:9 Drosophila melanogaster
intron_FBgn0036974:9_FBgn0036974:10 Drosophila melanogaster
intron_FBgn0036974:10_FBgn0036974:11 Drosophila melanogaster
intron_FBgn0036974:11_FBgn0036974:12 Drosophila melanogaster
intron_FBgn0036974:12_FBgn0036974:14 Drosophila melanogaster
intron_FBgn0036974:3_FBgn0036974:7 Drosophila melanogaster
intron_FBgn0036974:5_FBgn0036974:7 Drosophila melanogaster
intron_FBgn0036974:2_FBgn0036974:7 Drosophila melanogaster
intron_FBgn0036974:6_FBgn0036974:8 Drosophila melanogaster
intron_FBgn0036974:4_FBgn0036974:7 Drosophila melanogaster
intron_FBgn0036974:12_FBgn0036974:13 Drosophila melanogaster
intron_FBgn0036974:12_FBgn0036974:15 Drosophila melanogaster

28 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage eRF1 none -0.029039821   19067489
Lipid storage eRF1 none 1.7967313   19067489
Lipid storage eRF1 none 0.289711141   19067489
Drosophila C virus infection eRF1 Drosophila C virus replication down np   17040126
Innate immunity eRF1 Decreased IMD/Rel reporter activity -5.4   16170305
Hedgehog signaling eRF1 Decreased Hedgehog reporter activity -2.4   16311596
Cell size and cell-cycle regulation (1) eRF1 none sp   16496002
Muscle morphogenesis and function (1) eRF1 Lethal np   20220848
Muscle morphogenesis and function (3) eRF1 none np   20220848
Heat nociception (1) eRF1 none -1.17   21074052
Heart development and function (1) eRF1 Adult lethal 0.39   20371351
Notch pathway regulation (4) eRF1 Completely lethal (before pupal) sp   19363474
Hh pathway regulation eRF1 Downregulation of Hh pathway -0.313824021423172   17903264
Hh pathway regulation eRF1 none -0.112655138793329   17903264
Blood cell homeostasis regulation (1) eRF1 Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) eRF1 none np   20540764
Blood cell homeostasis regulation (3) eRF1 Increased melanotic mass formation 15.9   20540764
Blood cell homeostasis regulation (4) eRF1 none 0   20540764
Blood cell homeostasis regulation (5) eRF1 Increased melanotic mass formation 16.7   20540764
Blood cell homeostasis regulation (6) eRF1 Increased melanotic mass formation 32   20540764
Blood cell homeostasis regulation (7) eRF1 none 0   20540764
Blood cell homeostasis regulation (8) eRF1 Lethal np   20540764
RTK-Ras-ERK pathway regulation (1) eRF1 none 1.38 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) eRF1 Decreased ERK phosphorylation after EGF stimulation -2.09 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) eRF1 none 0.53 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) eRF1 none 1.04 30 minutes sSpitz stimulation 22028469
Glycosylation regulation (1) eRF1 Decreased (GlcNAc)n Chp glycosylation, decreased GlcNAcb1-4GlcNAc Chp glycosylation sp   21203496
Glycosylation regulation (2) eRF1 none np   21203496

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