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Gene : Hsc70-5 D. melanogaster

DB identifier  ? FBgn0001220 Secondary Identifier  ? CG8542
Name  ? Heat shock protein cognate 5 Source  FlyBase
  • synonyms:
  • Hsp-c5,
  • FBgn0022196,
  • Hsc-5,
  • FBan0008542,
  • FBgn0001220,
  • hsc70-5,
  • HSC-70,
  • Hsp cognate 5,
  • CG8542,
  • HSC5,
  • l(2)k04907,
  • dhsc70,
  • HSC70

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7 Alleles

DB identifier Symbol Allele Class Organism
FBal0183180 Hsc70-5[c05662]   Drosophila melanogaster
FBal0064522 Hsc70-5[k06618]   Drosophila melanogaster
FBal0064523 Hsc70-5[k04907]   Drosophila melanogaster
FBal0207334 Hsc70-5[GD13957]   Drosophila melanogaster
FBal0222850 Hsc70-5[d10092]   Drosophila melanogaster
FBal0230627 Hsc70-5[KK100233]   Drosophila melanogaster
FBal0276045 Hsc70-5[NIG.8542R]   Drosophila melanogaster

225 Clones

Secondary Identifier DB identifier
EK146110 FBcl0023378
EK199210 FBcl0023516
EK252659 FBcl0023536
EK193661 FBcl0023568
EK044360 FBcl0023576
EK118356 FBcl0023584
EK085956 FBcl0023590
EK290501 FBcl0023598
EK303740 FBcl0023606
EK229514 FBcl0023614
EK075042 FBcl0023622
EK122718 FBcl0023630
EK294508 FBcl0023670
EK143459 FBcl0024280
EK131031 FBcl0024688
EK213606 FBcl0024754
EK094238 FBcl0024822
EK042608 FBcl0025392
EK166441 FBcl0025402
EK094236 FBcl0025412
EK094257 FBcl0025418
EK234258 FBcl0025426
EK260856 FBcl0025434
EK249054 FBcl0025442
AT30537 FBcl0037135
AT26163 FBcl0037163
AT16255 FBcl0037185
AT24138 FBcl0037191
AT26686 FBcl0037195
AT11667 FBcl0037199

7 Exons

DB identifier Symbol
FBgn0001220:5 Hsc70-5:5
FBgn0001220:7 Hsc70-5:7
FBgn0001220:4 Hsc70-5:4
FBgn0001220:3 Hsc70-5:3
FBgn0001220:2 Hsc70-5:2
FBgn0001220:1 Hsc70-5:1
FBgn0001220:6 Hsc70-5:6

2 Transcripts

DB identifier Gene
FBtr0087568 Hsc70-5
FBtr0339969 Hsc70-5

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0087568-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339969-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087568-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339969-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
36583 NCBI Entrez Gene identifiers FBgn0001220
62333 BioGRID FBgn0001220

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2988.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 4156.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2160.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2899.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2794.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 3587.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3329.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3429.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1825.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3278.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2286.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1956.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1770.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2745.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2508.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 3252.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2132.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2931.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 3372.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2785.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 3487.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 4586.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2968.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 3619.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2723.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3154.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 820.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 837.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 978.0
FBgn0001220 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1380.0

6 Introns

DB identifier
Organism . Name
intron_FBgn0001220:7_FBgn0001220:5 Drosophila melanogaster
intron_FBgn0001220:5_FBgn0001220:4 Drosophila melanogaster
intron_FBgn0001220:4_FBgn0001220:3 Drosophila melanogaster
intron_FBgn0001220:3_FBgn0001220:2 Drosophila melanogaster
intron_FBgn0001220:2_FBgn0001220:1 Drosophila melanogaster
intron_FBgn0001220:6_FBgn0001220:5 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Hsc70-5 none 0.094512993   19067489
Lipid storage Hsc70-5 none 3.684018784   19067489
Chlamydia caviae infection Hsc70-5 Decreased Chlamydia caviae infection np   17967059
ERK signaling Hsc70-5 ERK activation increased weak   17086199
Cell size and cell-cycle regulation (1) Hsc70-5 none sp   16496002
Muscle morphogenesis and function (1) Hsc70-5 Lethal np   20220848
Muscle morphogenesis and function (2) Hsc70-5 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Muscle morphogenesis and function (3) Hsc70-5 none np   20220848
Heat nociception (1) Hsc70-5 Developmentally lethal -1.17   21074052
Heat nociception (1) Hsc70-5 none -0.21   21074052
Heart development and function (1) Hsc70-5 Adult lethal 0   20371351
Serratia marcescens infection (1) Hsc70-5 Decreased viability after Serratia marcescens infection -4.10714285714285   19520911
Serratia marcescens infection (2) Hsc70-5 Decreased viability after Serratia marcescens infection sp   19520911
Serratia marcescens infection (6) Hsc70-5 Larval lethality or failure to eclose np   19520911
Notch pathway regulation (4) Hsc70-5 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Hsc70-5 Completely lethal (pupal) sp   19363474
Adiposity regulation (1) Hsc70-5 none -0.078   20074523
RTK-Ras-ERK pathway regulation (1) Hsc70-5 none -0.06 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Hsc70-5 none -0.61 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Hsc70-5 none -0.38 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Hsc70-5 none 0.29 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Hsc70-5 none -0.12   23263283
Glycosylation regulation (1) Hsc70-5 Increased alpha1,3-fucose Chp glycosylation, increased mannose Chp glycosylation sp   21203496
Glycosylation regulation (2) Hsc70-5 Effect on Chp glycosylation np   21203496
Glycosylation regulation (3) Hsc70-5 Effect on Chp glycosylation np   21203496
Huntingtin (Htt) aggregates formation Hsc70-5 Increased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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