modENCODE |  Help |  blog

Gene : Rpt5 D. melanogaster

DB identifier  ? FBgn0028684 Secondary Identifier  ? CG10370
Name  ? Regulatory particle triple-A ATPase 5 Source  FlyBase
  • synonyms:
  • BcDNA.GH12068,
  • l(3)04210,
  • Pros26S,
  • Pros26S-RS6A,
  • FBgn0045868,
  • DmTBP-1,
  • p50,
  • FBgn0028684,
  • Rpt5,
  • TBP-1,
  • anon-WO0153538.10,
  • S6',
  • Dm_Rpt5a,
  • FBgn0045870,
  • FBgn0045946,
  • BcDNA:GH12068,
  • Proteasome 26S regulatory subunit 6A,
  • FBgn0010835,
  • Dm_Rpt5b,
  • anon-WO0153538.9,
  • FBgn0027925,
  • CG10370,
  • Tat-binding protein-1,
  • FBan0010370,
  • Tbp1,
  • dRpt5,
  • anon-WO0153538.8,
  • FBgn0026321

Sequence Feature Displayer

Publication Counts Displayer

Genomics

Gene Ontology Displayer

Homologue Displayer

Mod Mine G Browse Displayer

Overlapping Features Displayer

Regulatory Regions Displayer

9 Alleles

DB identifier Symbol Allele Class Organism
FBal0134136 Rpt5[dsRNA.cWa]   Drosophila melanogaster
FBal0286964 Rpt5[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286965 Rpt5[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0248178 Rpt5[HMS00417]   Drosophila melanogaster
FBal0208742 Rpt5[GD6960]   Drosophila melanogaster
FBal0181299 Rpt5[c01875]   Drosophila melanogaster
FBal0231504 Rpt5[KK101828]   Drosophila melanogaster
FBal0009505 Rpt5[04210b]   Drosophila melanogaster
FBal0215716 Rpt5[DG19608]   Drosophila melanogaster

60 Clones

Secondary Identifier DB identifier
AT19673 FBcl0004945
AT19890 FBcl0004953
AT08624 FBcl0004961
AT15772 FBcl0004969
UUGC1118 FBcl0005975
EC38686 FBcl0062351
EC40737 FBcl0062373
EC35387 FBcl0062385
EC36887 FBcl0069573
EN15932 FBcl0091991
GH12068 FBcl0119795
EK288809 FBcl0123444
EK094114 FBcl0123470
GM08220 FBcl0138363
GM06024 FBcl0138365
GM21364 FBcl0144411
GM20719 FBcl0144412
HL07443 FBcl0149698
LD22987 FBcl0170032
LD40560 FBcl0170061
LD39695 FBcl0171050
LD37061 FBcl0171870
LD36650 FBcl0172212
LP02182 FBcl0185556
RE15949 FBcl0215540
RE68431 FBcl0215577
RE12090 FBcl0216064
RE74033 FBcl0217680
RE55625 FBcl0218017
RE49987 FBcl0219214

3 Exons

DB identifier Symbol
FBgn0028684:1 Tbp-1:1
FBgn0028684:2 Tbp-1:2
FBgn0028684:3 Tbp-1:3

1 Transcripts

DB identifier Gene
FBtr0084452 Rpt5

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0084452-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0084452-3-prime-utr Drosophila melanogaster

Interactions

Cytoscape Network Displayer

 

Other

74 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42805 NCBI Entrez Gene identifiers FBgn0028684
67743 BioGRID FBgn0028684

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1558.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1772.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1383.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1651.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1687.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1161.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1319.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1068.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 916.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2287.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1498.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1280.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1518.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1313.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1305.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1347.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1316.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1266.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1477.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1595.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1193.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1950.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1239.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1446.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1028.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3728.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 935.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1394.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 999.0
FBgn0028684 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1025.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0028684:1_FBgn0028684:2 Drosophila melanogaster
intron_FBgn0028684:2_FBgn0028684:3 Drosophila melanogaster

27 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Rpt5 none 0.73746424   19067489
Lipid storage Rpt5 none 2.110128599   19067489
ERK signaling Rpt5 ERK activation reduced weak   17086199
Intracellular Listeria monocytogenes infection Rpt5 Decreased GFP protein expression strong   16020693
Constitutive protein secretion and Golgi organization (1) Rpt5 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Rpt5 Decreased G1 DNA content sp   16496002
Cell size and cell-cycle regulation (2) Rpt5 none 1.329   16496002
Cell size and cell-cycle regulation (3) Rpt5 Decreased cell number 415   16496002
Cell size and cell-cycle regulation (4) Rpt5 none below threshold   16496002
Candida albicans phagocytosis (1) Rpt5 none np   16336044
Lipid storage Rpt5 Fewer lipid droplets strong   18408709
Mutant human huntingtin aggregation Rpt5 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Rpt5 Lethal np   20220848
Muscle morphogenesis and function (2) Rpt5 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Notch pathway regulation (4) Rpt5 Completely lethal (pupal) sp   19363474
PGN-induced dJNK phosphorylation Rpt5 Increased P-JNK protein expression with PGN 2.51 15 min PGN induction 19893628
Notch induced transcription Rpt5 none 0.28993 without Notch stimulation 20959007
Notch induced transcription Rpt5 Upregulation of Notch pathway after Notch stimulation 2.4983 N(delta)ecn Notch stimulation 20959007
Notch induced transcription Rpt5 none 1.7144 N(delta)ecn Notch stimulation 20959007
S2 cell spreading Rpt5 none np   21041442
RTK-Ras-ERK pathway regulation (1) Rpt5 Decreased ERK phosphorylation after EGF stimulation -5.73 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Rpt5 Decreased ERK phosphorylation after EGF stimulation -3.62 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Rpt5 none -0.62 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Rpt5 Decreased ERK phosphorylation after sSpitz and EGF stimulation -3.09 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation Rpt5 none -1.61   23263283
Srp/Lz-induced transcriptional activation Rpt5 Decreased Srp/Lz-induced transcription -5.5   20368357
Huntingtin (Htt) aggregates formation Rpt5 Decreased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

0 Submissions