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Gene : Prosbeta4 D. melanogaster

DB identifier  ? FBgn0032596 Secondary Identifier  ? CG17331
Name  ? Proteasome beta4 subunit Source  FlyBase
  • synonyms:
  • 17331,
  • CG17331,
  • GC17331,
  • Prosbeta4,
  • PSMB2,
  • FBan0017331,
  • beta4,
  • Beta-4,
  • FBgn0032596

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7 Alleles

DB identifier Symbol Allele Class Organism
FBal0248146 Prosbeta4[HMS00384]   Drosophila melanogaster
FBal0287282 Prosbeta4[Scer\UAS.ORF]   Drosophila melanogaster
FBal0287283 Prosbeta4[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0162055 Prosbeta4[c05852]   Drosophila melanogaster
FBal0201845 Prosbeta4[GD8601]   Drosophila melanogaster
FBal0157141 Prosbeta4[dsRNA.cGa]   Drosophila melanogaster
FBal0272590 Prosbeta4[NIG.17331R]   Drosophila melanogaster

38 Clones

Secondary Identifier DB identifier
EC28422 FBcl0072225
EP05023 FBcl0088215
EK136351 FBcl0095010
EK277536 FBcl0095072
EK191042 FBcl0098938
EK032043 FBcl0098982
EK307735 FBcl0098994
EN02038 FBcl0101163
EN12012 FBcl0101165
GH01979 FBcl0119015
GH20163 FBcl0119021
GH08267 FBcl0119025
GM03626 FBcl0143438
HL07787 FBcl0149659
LD08176 FBcl0157831
LP06313 FBcl0186286
RE26877 FBcl0218357
RH72196 FBcl0256608
RH60732 FBcl0256611
RH39391 FBcl0259373
Dmel_neb_011319_0650_1035 FBcl0374657
Dmel_dig_014185_0637_2205 FBcl0374658
Dmel_dig_016673_0632_1524 FBcl0374659
Dmel_neb_003085_0827_2949 FBcl0374660
CK01.14D.B12 FBcl0431281
FGA007E06 FBcl0384407
FGA007D06 FBcl0384401
FGM228F05 FBcl0391314
FGM317D11 FBcl0393326
522446 FBcl0431127

4 Exons

DB identifier Symbol
FBgn0032596:4 CG17331:4
FBgn0032596:3 CG17331:3
FBgn0032596:2 CG17331:2
FBgn0032596:1 CG17331:1

2 Transcripts

DB identifier Gene
FBtr0080936 Prosbeta4
FBtr0335142 Prosbeta4

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0080936-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0335142-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080936-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0335142-3-prime-utr Drosophila melanogaster

Interactions

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Other

74 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34999 NCBI Entrez Gene identifiers FBgn0032596
61006 BioGRID FBgn0032596

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1767.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1775.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1387.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1460.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1088.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2182.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1621.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1516.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 794.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2823.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2042.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1436.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 959.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1100.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2005.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1911.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1738.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1086.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2259.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1686.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1387.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2627.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1814.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1586.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2396.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 4942.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 3939.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1992.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1927.0
FBgn0032596 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1138.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0032596:4_FBgn0032596:3 Drosophila melanogaster
intron_FBgn0032596:3_FBgn0032596:2 Drosophila melanogaster
intron_FBgn0032596:3_FBgn0032596:1 Drosophila melanogaster

43 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Prosbeta4 Increased lipid droplet area 7.249708164   19067489
Lipid storage Prosbeta4 Increased lipid droplet area 2.679970868   19067489
ERK signaling Prosbeta4 ERK activation reduced weak   17086199
Intracellular Listeria monocytogenes infection Prosbeta4 Decreased GFP protein expression moderate   16020693
Hedgehog signaling Prosbeta4 Decreased Hedgehog reporter activity -2.67   16311596
Mycobacterial infection (1) - M. fortuitum infection Prosbeta4 Decreased M. fortuitum intracellular infection 6.8 measurement after 3 days 16020694
Mycobacterial infection (2) - E. coli phagocytosis Prosbeta4 Decreased E. coli phagocytosis np   16020694
Constitutive protein secretion and Golgi organization (1) Prosbeta4 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Prosbeta4 none sp   16496002
Candida albicans phagocytosis (1) Prosbeta4 none np   16336044
Combinatorial effect with methyl methanesulphonate (1) Prosbeta4 none sp   19543366
Combinatorial effect with methyl methanesulphonate (2) Prosbeta4 Synthetic lethal with methyl methanesulphonate sp   19543366
Mutant human huntingtin aggregation Prosbeta4 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Prosbeta4 Lethal np   20220848
Muscle morphogenesis and function (1) Prosbeta4 Lethal np   20220848
Muscle morphogenesis and function (3) Prosbeta4 Clumpy Z-line (irregular aggregates) np   20220848
Heat nociception (1) Prosbeta4 none -1.17   21074052
Heat nociception (1) Prosbeta4 Developmentally lethal -1.17   21074052
Heart development and function (1) Prosbeta4 Pupal lethal 0   20371351
Serratia marcescens infection (1) Prosbeta4 none -0.229508196721311   19520911
Notch pathway regulation (4) Prosbeta4 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Prosbeta4 Completely lethal (before pupal) sp   19363474
Hh pathway regulation Prosbeta4 none 0.0402480811620865   17903264
Hh pathway regulation Prosbeta4 none 0.153340914721427   17903264
Adiposity regulation (1) Prosbeta4 Decreased triglyceride expression -0.642   20074523
Adiposity regulation (2) Prosbeta4 Lethal or developmental delay d/l   20074523
Adiposity regulation (3) Prosbeta4 Lethal or developmental delay d/l   20074523
Adiposity regulation (4) Prosbeta4 Lethal or developmental delay d/l   20074523
Adiposity regulation (5) Prosbeta4 Decreased triglyceride expression -0.385   20074523
Blood cell homeostasis regulation (1) Prosbeta4 Increased melanotic mass formation np   20540764

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