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Gene : Prosalpha3 D. melanogaster

DB identifier  ? FBgn0261394 Secondary Identifier  ? CG9327
Name  ? Proteasome alpha3 subunit Source  FlyBase
  • synonyms:
  • Pros29,
  • alpha-subunit of 20S proteasome,
  • Alpha-3,
  • FBgn0261394,
  • alpha3,
  • Proteasome subunit alpha-type 4,
  • PROS-29,
  • FBgn0041193,
  • Prosalpha3,
  • PSB3_DROME,
  • CG9327,
  • alpha3_dm,
  • FBan0009327,
  • Pros20S-alpha3,
  • 20S proteasome,
  • Proteasome 20S alpha3 subunit,
  • FBgn0003150,
  • Proteasome 29kD subunit

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8 Alleles

DB identifier Symbol Allele Class Organism
FBal0286767 Prosalpha3[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286768 Prosalpha3[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0239095 Prosalpha3[T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0214699 Prosalpha3[GD14188]   Drosophila melanogaster
FBal0156045 Prosalpha3[dsRNA.cGa]   Drosophila melanogaster
FBal0235301 Prosalpha3[KK108002]   Drosophila melanogaster
FBal0193266 Prosalpha3[Scer\UAS.cMa]   Drosophila melanogaster
FBal0276373 Prosalpha3[NIG.9327R]   Drosophila melanogaster

159 Clones

Secondary Identifier DB identifier
AT26790 FBcl0019503
AT09516 FBcl0019589
AT11726 FBcl0019609
AT19240 FBcl0019635
AT09749 FBcl0019679
AT24452 FBcl0019683
AT31583 FBcl0019697
ESG017c.B21.1_E08 FBcl0004549
EK162228 FBcl0047890
EK172836 FBcl0047898
bs46h09 FBcl0050545
bs46a04 FBcl0051341
GH07868 FBcl0114249
GH08224 FBcl0114253
GH26587 FBcl0114303
GM03917 FBcl0140567
GM16453 FBcl0145564
LD09523 FBcl0155136
LD45393 FBcl0168569
LD41156 FBcl0168590
LD29759 FBcl0168595
LP19881 FBcl0183553
LP10005 FBcl0183584
LP12129 FBcl0183587
LP03757 FBcl0183588
LP02028 FBcl0183596
LP09450 FBcl0183604
LP05917 FBcl0183609
LP13137 FBcl0183611
LP08468 FBcl0183613

3 Exons

DB identifier Symbol
FBgn0261394:1 Pros29:1
FBgn0261394:2 Pros29:2
FBgn0261394:3 Pros29:3

1 Transcripts

DB identifier Gene
FBtr0071522 Prosalpha3

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0071522-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0071522-3-prime-utr Drosophila melanogaster

Interactions

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74 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
37378 NCBI Entrez Gene identifiers FBgn0261394
63019 BioGRID FBgn0261394

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

2 Introns

DB identifier
Organism . Name
intron_FBgn0261394:1_FBgn0261394:2 Drosophila melanogaster
intron_FBgn0261394:2_FBgn0261394:3 Drosophila melanogaster

18 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Prosalpha3 none 0.469551063   19067489
Lipid storage Prosalpha3 none 2.644022763   19067489
Hedgehog signaling Prosalpha3 Decreased Hedgehog reporter activity -2.24   16311596
Constitutive protein secretion and Golgi organization (1) Prosalpha3 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Prosalpha3 none sp   16496002
Candida albicans phagocytosis (1) Prosalpha3 none np   16336044
Combinatorial effect with methyl methanesulphonate (2) Prosalpha3 none sp   19543366
Mutant human huntingtin aggregation Prosalpha3 Decreased mutant human huntingtin aggregation <= -2   19789644
Hh pathway regulation Prosalpha3 none -0.212563654142677   17903264
Hh pathway regulation Prosalpha3 none -0.177945300430602   17903264
Blood cell homeostasis regulation (1) Prosalpha3 none np   20540764
Blood cell homeostasis regulation (2) Prosalpha3 none np   20540764
RTK-Ras-ERK pathway regulation (1) Prosalpha3 Decreased ERK phosphorylation after EGF stimulation -1.56 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Prosalpha3 Decreased ERK phosphorylation after EGF stimulation -3.56 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Prosalpha3 none 0.83 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Prosalpha3 none 1.22 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation Prosalpha3 none -1.73   23263283
Glycosylation regulation (1) Prosalpha3 Lethal np   21203496

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