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Gene : AP-1-2beta D. melanogaster

DB identifier  ? FBgn0010380 Secondary Identifier  ? CG12532
Name  ? Adaptor Protein complex 1/2, beta subunit Source  FlyBase
  • synonyms:
  • FBgn0010380,
  • CG12532,
  • FBan0012532,
  • apl2,
  • AP1beta1,
  • BAP,
  • AP2beta2,
  • Beta Adaptin,
  • BAD1,
  • Beta-adaptin,
  • AP-1-2beta,
  • AP-2beta,
  • AP-beta1,
  • AP-1/2beta,
  • beta1/2,
  • AP-1beta1,
  • apl1,
  • Beta Adaptin Drosophila 1

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6 Alleles

DB identifier Symbol Allele Class Organism
FBal0198821 AP-1-2beta[GD1204]   Drosophila melanogaster
FBal0239465 AP-1-2beta[JF02963]   Drosophila melanogaster
FBal0245316 AP-1-2beta[HM04014]   Drosophila melanogaster
FBal0267844 AP-1-2beta[NIG.12532R]   Drosophila melanogaster
FBal0136139 AP-1-2beta[dsRNA.cRa]   Drosophila melanogaster
FBal0287581 AP-1-2beta[GH73] loss of function allele Drosophila melanogaster

102 Clones

Secondary Identifier DB identifier
AT31751 FBcl0017157
AT20552 FBcl0017171
AT02878 FBcl0017217
AT21431 FBcl0017249
CK00332 FBcl0059493
GH16735 FBcl0103103
EK305619 FBcl0106266
EK134947 FBcl0106300
EK215331 FBcl0106360
GH19661 FBcl0110847
GH04140 FBcl0111111
GH18829 FBcl0111119
GH03387 FBcl0111123
GH22718 FBcl0111125
GH05311 FBcl0111129
GH12721 FBcl0111131
GH24463 FBcl0111133
GH18291 FBcl0111135
GH19016 FBcl0111137
GH13367 FBcl0111139
GH03043 FBcl0111141
GH17739 FBcl0111143
HL03706 FBcl0149182
LD04106 FBcl0153926
LD11191 FBcl0153936
LD01870 FBcl0153939
LD24238 FBcl0167117
LD35332 FBcl0167121
LD28376 FBcl0167123
LD25553 FBcl0167124

3 Exons

DB identifier Symbol
FBgn0010380:1 Bap:1
FBgn0010380:2 Bap:2
FBgn0010380:3 Bap:3

1 Transcripts

DB identifier Gene
FBtr0074789 AP-1-2beta

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0074789-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0074789-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
32987 NCBI Entrez Gene identifiers FBgn0010380
59282 BioGRID FBgn0010380

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1444.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1709.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1493.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2977.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1968.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1219.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1290.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1905.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1050.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1656.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1667.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 931.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1627.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1757.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1556.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1310.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1728.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 783.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1642.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1603.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1474.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1758.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1471.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1369.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1121.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1855.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1623.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1070.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1030.0
FBgn0010380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1182.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0010380:1_FBgn0010380:2 Drosophila melanogaster
intron_FBgn0010380:2_FBgn0010380:3 Drosophila melanogaster

22 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage AP-1-2beta none -0.068062285   19067489
Lipid storage AP-1-2beta none 0.339903076   19067489
ERK signaling AP-1-2beta ERK activation increased strong   17086199
E. coli / S. aureus infection AP-1-2beta Decreased phagocytosis np   11912489
Cell size and cell-cycle regulation (1) AP-1-2beta none sp   16496002
Muscle morphogenesis and function (1) AP-1-2beta Day 7 lethal np   20220848
Muscle morphogenesis and function (1) AP-1-2beta Lethal np   20220848
Heat nociception (1) AP-1-2beta Increased noxious heat avoidance, lethal 8.66   21074052
Heart development and function (1) AP-1-2beta Embryonic lethal or no offspring 0   20371351
Heart development and function (1) AP-1-2beta Embryonic lethal or no offspring 0.5   20371351
Heart development and function (2) AP-1-2beta Decreased viability 7.47   20371351
Serratia marcescens infection (1) AP-1-2beta none 0.378378378378378   19520911
Notch pathway regulation (4) AP-1-2beta Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) AP-1-2beta Completely lethal (pupal) sp   19363474
Adiposity regulation (1) AP-1-2beta none -0.627   20074523
RTK-Ras-ERK pathway regulation (1) AP-1-2beta none -0.27 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) AP-1-2beta none 0.62 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) AP-1-2beta none -0.08 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) AP-1-2beta none -0.08 30 minutes sSpitz stimulation 22028469
Wg pathway regulation (1) AP-1-2beta Decreased WgRluc and not changed sFluc protein expression medium   21886182
Hippo pathway regulation AP-1-2beta none -0.01   23263283
Glycosylation regulation (1) AP-1-2beta none sp   21203496

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