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Gene : Rpt4 D. melanogaster

DB identifier  ? FBgn0028685 Secondary Identifier  ? CG3455
Name  ? Regulatory particle triple-A ATPase 4 Source  FlyBase
  • synonyms:
  • l(1)G0345,
  • Dm_Rpt4a,
  • Rpt4,
  • FBgn0027213,
  • S10b,
  • Dm_Rpt4b,
  • FBan0003455,
  • CG3455,
  • p42D,
  • l(1)G0227,
  • FBgn0028685,
  • Dmp42D,
  • l(1)G0114,
  • FBgn0029070,
  • FBgn0040197

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10 Alleles

DB identifier Symbol Allele Class Organism
FBal0282323 Rpt4[Scer\UAS.cGa]   Drosophila melanogaster
FBal0257345 Rpt4[HMS00661]   Drosophila melanogaster
FBal0286479 Rpt4[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286480 Rpt4[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0098106 Rpt4[G0345]   Drosophila melanogaster
FBal0102648 Rpt4[G0227]   Drosophila melanogaster
FBal0103768 Rpt4[G0114]   Drosophila melanogaster
FBal0208416 Rpt4[GD10973]   Drosophila melanogaster
FBal0208417 Rpt4[GD17124]   Drosophila melanogaster
FBal0222946 Rpt4[CB-0534-3]   Drosophila melanogaster

69 Clones

Secondary Identifier DB identifier
UUGC0181 FBcl0001315
UUGC0227 FBcl0001391
CK01666 FBcl0060013
EK249861 FBcl0084890
EK256153 FBcl0086464
EK190329 FBcl0086486
EK243226 FBcl0086496
EK183402 FBcl0086500
EK035244 FBcl0086546
EK046664 FBcl0086558
EK065247 FBcl0086604
GH13263 FBcl0126275
GH22143 FBcl0126279
GH21978 FBcl0126285
GH10495 FBcl0126291
GM04250 FBcl0142223
LD08217 FBcl0151235
LD04678 FBcl0151337
LD02047 FBcl0159425
LD26237 FBcl0163366
LD36039 FBcl0163697
LD38867 FBcl0174275
LD26675 FBcl0174287
LD45915 FBcl0174703
LP08208 FBcl0179536
LP02416 FBcl0187826
LP07360 FBcl0187832
LP18657 FBcl0187835
LP16188 FBcl0187839
LP08493 FBcl0187844

5 Exons

DB identifier Symbol
FBgn0028685:1 Rpt4:1
FBgn0028685:5 Rpt4:5
FBgn0028685:4 Rpt4:4
FBgn0028685:3 Rpt4:3
FBgn0028685:2 Rpt4:2

1 Transcripts

DB identifier Gene
FBtr0305495 Rpt4

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0305495-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0305495-3-prime-utr Drosophila melanogaster

Interactions

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Other

74 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31567 NCBI Entrez Gene identifiers FBgn0028685
58056 BioGRID FBgn0028685

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1784.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2072.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1325.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1716.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1973.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2096.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2114.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1941.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1470.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3063.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1922.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1729.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1323.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2003.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1766.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2219.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1953.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1389.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2495.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2126.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1211.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1839.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2034.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1336.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1645.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 4726.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 4119.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2933.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1547.0
FBgn0028685 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1260.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0028685:5_FBgn0028685:4 Drosophila melanogaster
intron_FBgn0028685:4_FBgn0028685:3 Drosophila melanogaster
intron_FBgn0028685:3_FBgn0028685:2 Drosophila melanogaster
intron_FBgn0028685:2_FBgn0028685:1 Drosophila melanogaster

36 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Rpt4 none 0.526833401   19067489
Lipid storage Rpt4 none -0.382855994   19067489
ERK signaling Rpt4 ERK activation reduced weak   17086199
Intracellular Listeria monocytogenes infection Rpt4 Decreased GFP protein expression strong   16020693
Hedgehog signaling Rpt4 Decreased Hedgehog reporter activity -2.06   16311596
Cell size and cell-cycle regulation (1) Rpt4 Decreased G1 DNA content, decreased viability sp   16496002
Cell size and cell-cycle regulation (2) Rpt4 none 0.963   16496002
Cell size and cell-cycle regulation (3) Rpt4 Decreased cell number 395   16496002
Cell size and cell-cycle regulation (4) Rpt4 Increased number of mitotic cells 1   16496002
Candida albicans phagocytosis (1) Rpt4 none np   16336044
Lipid storage Rpt4 Fewer lipid droplets strong   18408709
Combinatorial effect with methyl methanesulphonate (2) Rpt4 none sp   19543366
Mutant human huntingtin aggregation Rpt4 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Rpt4 Lethal np   20220848
Muscle morphogenesis and function (3) Rpt4 none np   20220848
Heat nociception (1) Rpt4 Developmentally lethal 1.6   21074052
Regulated secretory pathway biogenesis (1) Rpt4 none 1.7   21149569
Heart development and function (1) Rpt4 none 0.9   20371351
Heart development and function (1) Rpt4 Developmentally lethal 0.5   20371351
Heart development and function (2) Rpt4 Decreased viability 4.08   20371351
Serratia marcescens infection (1) Rpt4 none -1.28148148148148   19520911
Notch pathway regulation (4) Rpt4 Completely lethal (before pupal) sp   19363474
PGN-induced dJNK phosphorylation Rpt4 Increased P-JNK protein expression with PGN 2.28 15 min PGN induction 19893628
PGN-induced dJNK phosphorylation Rpt4 Increased P-JNK protein expression with PGN 2.28 60 min PGN induction 19893628
Notch induced transcription Rpt4 none 0.72527 without Notch stimulation 20959007
Notch induced transcription Rpt4 Upregulation of Notch pathway after Notch stimulation 2.5225 N(delta)ecn Notch stimulation 20959007
Notch induced transcription Rpt4 none 0.16673 N(delta)ecn Notch stimulation 20959007
Hh pathway regulation Rpt4 none -0.216312924595637   17903264
Hh pathway regulation Rpt4 none -0.154959007644571   17903264
Self-renewal and differentiation in neural stem cells Rpt4 GFP aggregates number, GFP aggregates size, neuroblast abnormally large cell size, neuroblast larger cell size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with larger neurobl sp   21549331

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