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Gene : Nup153 D. melanogaster

DB identifier  ? FBgn0061200 Secondary Identifier  ? CG4453
Name  ? Nucleoporin 153kD Source  FlyBase
  • synonyms:
  • CG4453,
  • Nucleoporin 153,
  • FBgn0030762,
  • FBan0004453,
  • Nup 153,
  • FBgn0061200,
  • dmNup153,
  • dNup153,
  • NUP153

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7 Alleles

DB identifier Symbol Allele Class Organism
FBal0241738 Nup153[HM05248]   Drosophila melanogaster
FBal0257216 Nup153[HMS00527]   Drosophila melanogaster
FBal0246876 Nup153[G1713]   Drosophila melanogaster
FBal0207805 Nup153[GD10636]   Drosophila melanogaster
FBal0212649 Nup153[dsRNA.cMa]   Drosophila melanogaster
FBal0222217 Nup153[NP2104]   Drosophila melanogaster
FBal0236671 Nup153[KK110135]   Drosophila melanogaster

86 Clones

Secondary Identifier DB identifier
EP21219 FBcl0075679
EP16212 FBcl0075715
EP13917 FBcl0075801
EK059660 FBcl0117610
EK262424 FBcl0117614
EK131918 FBcl0117632
EK094805 FBcl0117666
EK150442 FBcl0117670
EK181931 FBcl0117704
EK086308 FBcl0117734
EK068851 FBcl0117738
EK305908 FBcl0117742
EK049910 FBcl0117746
EK091213 FBcl0117750
EK124839 FBcl0117754
EK223355 FBcl0117758
EK180430 FBcl0117764
EK135862 FBcl0117768
EK234013 FBcl0117772
EK139134 FBcl0117776
EK291637 FBcl0118708
EK069617 FBcl0118748
EK301754 FBcl0118768
EK040411 FBcl0118774
EK074919 FBcl0118796
EK002342 FBcl0118830
EK229312 FBcl0118844
EK168314 FBcl0118848
EK121754 FBcl0118852
HL02236 FBcl0149089

10 Exons

DB identifier Symbol
FBgn0061200:1 Nup153:1
FBgn0061200:3 Nup153:3
FBgn0061200:4 Nup153:4
FBgn0061200:5 Nup153:5
FBgn0061200:6 Nup153:6
FBgn0061200:7 Nup153:7
FBgn0061200:9 Nup153:9
FBgn0061200:10 Nup153:10
FBgn0061200:2 Nup153:2
FBgn0061200:8 Nup153:8

3 Transcripts

DB identifier Gene
FBtr0074284 Nup153
FBtr0340158 Nup153
FBtr0299587 Nup153

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0074284-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340158-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299587-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0074284-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340158-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299587-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
32630 NCBI Entrez Gene identifiers FBgn0061200
58967 BioGRID FBgn0061200

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1127.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1581.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1251.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1022.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 918.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 920.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1513.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1577.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 692.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1222.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1354.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1005.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 906.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1140.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1182.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1087.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1529.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1288.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 967.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1065.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 932.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1256.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1086.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1173.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1007.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3963.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 3793.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3032.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1984.0
FBgn0061200 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1578.0

10 Introns

DB identifier
Organism . Name
intron_FBgn0061200:1_FBgn0061200:3 Drosophila melanogaster
intron_FBgn0061200:3_FBgn0061200:4 Drosophila melanogaster
intron_FBgn0061200:4_FBgn0061200:5 Drosophila melanogaster
intron_FBgn0061200:5_FBgn0061200:6 Drosophila melanogaster
intron_FBgn0061200:6_FBgn0061200:7 Drosophila melanogaster
intron_FBgn0061200:7_FBgn0061200:8 Drosophila melanogaster
intron_FBgn0061200:8_FBgn0061200:9 Drosophila melanogaster
intron_FBgn0061200:9_FBgn0061200:10 Drosophila melanogaster
intron_FBgn0061200:7_FBgn0061200:9 Drosophila melanogaster
intron_FBgn0061200:2_FBgn0061200:4 Drosophila melanogaster

37 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Nup153 Decreased lipid droplet area 1.081596457   19067489
Lipid storage Nup153 Decreased lipid droplet area 1.689284214   19067489
Lipid storage Nup153 Decreased lipid droplet area -2.066847616   19067489
Lipid storage Nup153 Decreased lipid droplet area -2.32351378   19067489
ERK signaling Nup153 ERK activation reduced weak   17086199
Intracellular Listeria monocytogenes infection Nup153 Increased GFP protein expression moderate   16020693
Hedgehog signaling Nup153 Decreased Hedgehog reporter activity -2.16   16311596
Hedgehog signaling Nup153 Decreased Hedgehog reporter activity -3.18   16311596
Constitutive protein secretion and Golgi organization (1) Nup153 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Nup153 none sp   16496002
Cell size and cell-cycle regulation (1) Nup153 none sp   16496002
Influenza replication Nup153 Decreased Influenza replication -0.79/-2.59   18615016
Microtubule assembly and organization Nup153 none np   18463163
Mutant human huntingtin aggregation Nup153 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Nup153 Lethal np   20220848
Heat nociception (1) Nup153 Increased noxious heat avoidance, lethal 1.93   21074052
Heart development and function (1) Nup153 none 0.75   20371351
Heart development and function (2) Nup153 Decreased viability 10.21   20371351
Serratia marcescens infection (1) Nup153 Decreased viability after Serratia marcescens infection -2.68918918918918   19520911
Serratia marcescens infection (2) Nup153 none sp   19520911
Serratia marcescens infection (4) Nup153 Decreased viability after Serratia marcescens infection sp   19520911
Serratia marcescens infection (5) Nup153 Lethal np   19520911
Notch pathway regulation (4) Nup153 Completely lethal (before pupal) sp   19363474
Hh pathway regulation Nup153 none -0.204341438762354   17903264
Hh pathway regulation Nup153 none -0.125282231789296   17903264
Self-renewal and differentiation in neural stem cells Nup153 GFP aggregates number, GFP aggregates size, neuroblast cell shape, ganglion mother cell shorter lineages, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) Nup153 Decreased triglyceride expression -1   20074523
Adiposity regulation (2) Nup153 Lethal or developmental delay d/l   20074523
Adiposity regulation (3) Nup153 Lethal or developmental delay d/l   20074523
Adiposity regulation (4) Nup153 Lethal or developmental delay d/l   20074523

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