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Gene : fzy D. melanogaster

DB identifier  ? FBgn0001086 Secondary Identifier  ? CG4274
Name  ? fizzy Source  FlyBase
  • synonyms:
  • Cdc20/Fizzy,
  • BG:DS02740.14,
  • Fzy/Cdc20,
  • Cdc20[Fzy],
  • FZY,
  • Cdc20/Fzy,
  • FBan0004274,
  • Fizzy,
  • dFZY,
  • FBgn0001086,
  • dCDC20,
  • Cdc20[fizzy],
  • CDC20,
  • CG4274

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26 Alleles

DB identifier Symbol Allele Class Organism
FBal0281345 fzy[HMJ02068 ]   Drosophila melanogaster
FBal0245377 fzy[HM04081]   Drosophila melanogaster
FBal0257634 fzy[HMS00964]   Drosophila melanogaster
FBal0101412 fzy[EP1028]   Drosophila melanogaster
FBal0278598 fzy[GL00687]   Drosophila melanogaster
FBal0286603 fzy[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286604 fzy[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0061393 fzy[tDa]   Drosophila melanogaster
FBal0004955 fzy[1] amorphic allele - genetic evidence Drosophila melanogaster
FBal0034717 fzy[ID]   Drosophila melanogaster
FBal0086586 fzy[unspecified]   Drosophila melanogaster
FBal0031374 fzy[5] heat sensitive hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0031375 fzy[6] heat sensitive hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0061395 fzy[8]   Drosophila melanogaster
FBal0031372 fzy[3] amorphic allele - genetic evidence Drosophila melanogaster
FBal0031373 fzy[4] heat sensitive hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0004956 fzy[2] amorphic allele - genetic evidence Drosophila melanogaster
FBal0031376 fzy[7] heat sensitive hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0104613 fzy[dsRNA.cHa]   Drosophila melanogaster
FBal0262908 fzy[GL00442]   Drosophila melanogaster
FBal0197698 fzy[dsRNA.cMa]   Drosophila melanogaster
FBal0064874 fzy[Scer\UAS.cSa]   Drosophila melanogaster
FBal0179674 fzy[Ubi-p63E.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0209619 fzy[GD11268]   Drosophila melanogaster
FBal0279213 fzy[HMS02181]   Drosophila melanogaster
FBal0231216 fzy[KK101352]   Drosophila melanogaster

133 Clones

Secondary Identifier DB identifier
UUGC0256 FBcl0001453
UUGC0259 FBcl0001457
ESG012d.E21_C07 FBcl0008317
AT23782 FBcl0040539
AT03715 FBcl0040543
AT30869 FBcl0040545
AT05305 FBcl0040549
EK114338 FBcl0100854
EK117510 FBcl0101012
EK213833 FBcl0101298
EK159458 FBcl0101704
GH02903 FBcl0122217
GM10572 FBcl0143326
GM02166 FBcl0143367
LD13309 FBcl0157980
LD14034 FBcl0157983
LD08545 FBcl0157986
LD18190 FBcl0157988
LD08754 FBcl0157990
LD12520 FBcl0158059
LD18042 FBcl0158061
LD11224 FBcl0158062
LD30572 FBcl0172213
LD39303 FBcl0172214
LD43828 FBcl0172216
LD38169 FBcl0172221
LD24735 FBcl0172225
LD23923 FBcl0172229
LD42559 FBcl0172230
LD46217 FBcl0172232

3 Exons

DB identifier Symbol
FBgn0001086:1 fzy:1
FBgn0001086:2 fzy:2
FBgn0001086:3 fzy:3

1 Transcripts

DB identifier Gene
FBtr0080833 fzy

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0080833-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080833-3-prime-utr Drosophila melanogaster

Interactions

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Other

44 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34968 NCBI Entrez Gene identifiers FBgn0001086
60979 BioGRID FBgn0001086

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 979.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1134.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1343.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1590.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1621.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1576.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 805.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1207.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1368.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2161.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1519.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2783.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1511.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2019.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1125.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 941.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1295.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1271.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1597.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1071.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1146.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1133.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 825.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 841.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 791.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3896.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 5039.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 5545.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2933.0
FBgn0001086 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2384.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0001086:1_FBgn0001086:2 Drosophila melanogaster
intron_FBgn0001086:2_FBgn0001086:3 Drosophila melanogaster

33 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage fzy none 2.079165329   19067489
Lipid storage fzy none 1.257971325   19067489
ERK signaling fzy ERK activation reduced strong   17086199
Cell morphology fzy Morphology np   14527345
Intracellular Listeria monocytogenes infection fzy Increased GFP protein expression moderate   16020693
Constitutive protein secretion and Golgi organization (1) fzy Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) fzy none sp   16496002
Cell size and cell-cycle regulation (1) fzy Decreased G2 DNA content, decreased G1 cell size, decreased viability sp   16496002
Cell size and cell-cycle regulation (2) fzy none 1.444   16496002
Cell size and cell-cycle regulation (3) fzy none 473   16496002
Candida albicans phagocytosis (1) fzy Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) fzy Decreased Escherichia coli phagocytosis 20   16336044
Candida albicans phagocytosis (3) fzy none 47   16336044
Microtubule assembly and organization fzy Spindle poles splayed, chromosome condensation defect, chromosome alignment defect, increased number of cells in prometaphase np   18463163
Mutant human huntingtin aggregation fzy Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) fzy Lethal np   20220848
Muscle morphogenesis and function (1) fzy none np   20220848
Muscle morphogenesis and function (2) fzy Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) fzy none -0.02   21074052
Heat nociception (1) fzy none -1.17   21074052
Heart development and function (1) fzy none 0.75   20371351
Heart development and function (2) fzy Decreased viability 3.37   20371351
Serratia marcescens infection (1) fzy none -0.6875   19520911
Notch pathway regulation (4) fzy Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) fzy Bristle morphology defects, notum malformation death sp   19363474
Self-renewal and differentiation in neural stem cells fzy GFP aggregates number, GFP aggregates size, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast underproliferation, lethal sp   21549331
Self-renewal and differentiation in neural stem cells fzy GFP aggregates number, GFP aggregates size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with unchanged neuroblast cell size, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) fzy none -0.059   20074523
RTK-Ras-ERK pathway regulation (1) fzy Decreased ERK phosphorylation after EGF stimulation -4.98 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) fzy none -1.47 0 minutes EGF stimulation 22028469

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