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Gene : Actn D. melanogaster

DB identifier  ? FBgn0000667 Secondary Identifier  ? CG4376
Name  ? alpha actinin Source  FlyBase
  • synonyms:
  • fliA,
  • FBgn0000667,
  • alphaActn,
  • HM-29,
  • flightless A,
  • l(1)2Cb,
  • lethal(1)2cb,
  • l(1)EA82,
  • a-actinin,
  • FBan0004376,
  • Alpha-actinin,
  • CG4376,
  • EG:133E12.1,
  • ACTN,
  • y,
  • CT14232,
  • GA17,
  • flightless-A,
  • CT14163,
  • alpha actinin

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44 Alleles

DB identifier Symbol Allele Class Organism
FBal0211606 Actn[CC01961]   Drosophila melanogaster
FBal0176422 Actn[WG1118]   Drosophila melanogaster
FBal0162829 Actn[EY14992]   Drosophila melanogaster
FBal0188256 Actn[d08251]   Drosophila melanogaster
FBal0162830 Actn[EY02029]   Drosophila melanogaster
FBal0131808 Actn[EP1193]   Drosophila melanogaster
FBal0259146 Actn[KK102286]   Drosophila melanogaster
FBal0097427 Actn[G0077]   Drosophila melanogaster
FBal0125509 Actn[G0100]   Drosophila melanogaster
FBal0137674 Actn[KG06473]   Drosophila melanogaster
FBal0192543 Actn[EY20057]   Drosophila melanogaster
FBal0083658 Actn[800F22]   Drosophila melanogaster
FBal0000283 Actn[9] amorphic allele - genetic evidence Drosophila melanogaster
FBal0000280 Actn[6] amorphic allele - genetic evidence Drosophila melanogaster
FBal0000279 Actn[5] amorphic allele - genetic evidence Drosophila melanogaster
FBal0000275 Actn[1]   Drosophila melanogaster
FBal0176423 Actn[RpS27A.PD]   Drosophila melanogaster
FBal0000278 Actn[4]   Drosophila melanogaster
FBal0176426 Actn[Delta208]   Drosophila melanogaster
FBal0000290 Actn[16]   Drosophila melanogaster
FBal0000276 Actn[2]   Drosophila melanogaster
FBal0000287 Actn[13]   Drosophila melanogaster
FBal0000291 Actn[17]   Drosophila melanogaster
FBal0000292 Actn[18]   Drosophila melanogaster
FBal0000286 Actn[12]   Drosophila melanogaster
FBal0000288 Actn[14]   Drosophila melanogaster
FBal0000282 Actn[8] amorphic allele - genetic evidence Drosophila melanogaster
FBal0000293 Actn[19]   Drosophila melanogaster
FBal0000284 Actn[10]   Drosophila melanogaster
FBal0176424 Actn[KA21]   Drosophila melanogaster

95 Clones

Secondary Identifier DB identifier
ESG0115b.B21_C02 FBcl0001879
ESG0119b.B21_E07 FBcl0002105
ESG0113a.B21_H02 FBcl0002179
ESG013d.E21_D03 FBcl0010581
EC00291 FBcl0062893
EC00191 FBcl0062903
EK117319 FBcl0070678
EK237414 FBcl0070708
EK116129 FBcl0070720
EK097804 FBcl0070740
EK104911 FBcl0070748
EK245809 FBcl0070766
EK221226 FBcl0070778
EK209529 FBcl0070826
EK009513 FBcl0070846
EK281517 FBcl0070854
EK151850 FBcl0070864
EK117508 FBcl0070874
EK241120 FBcl0070892
EK111758 FBcl0070914
EK262033 FBcl0070924
EK180755 FBcl0070932
EK169117 FBcl0070944
EK229646 FBcl0070956
EK258715 FBcl0070968
EK200234 FBcl0071032
EK190264 FBcl0071062
EK305621 FBcl0071154
EK072644 FBcl0071312
EK308521 FBcl0071506

19 Exons

DB identifier Symbol
FBgn0000667:10 Actn:10
FBgn0000667:16 Actn:16
FBgn0000667:18 Actn:18
FBgn0000667:15 Actn:15
FBgn0000667:12 Actn:12
FBgn0000667:11 Actn:11
FBgn0000667:9 Actn:9
FBgn0000667:7 Actn:7
FBgn0000667:6 Actn:6
FBgn0000667:5 Actn:5
FBgn0000667:3 Actn:3
FBgn0000667:2 Actn:2
FBgn0000667:4 Actn:4
FBgn0000667:17 Actn:17
FBgn0000667:14 Actn:14
FBgn0000667:19 Actn:19
FBgn0000667:8 Actn:8
FBgn0000667:1 Actn:1
FBgn0000667:13 Actn:13

9 Transcripts

DB identifier Gene
FBtr0070343 Actn
FBtr0070344 Actn
FBtr0303048 Actn
FBtr0333801 Actn
FBtr0310659 Actn
FBtr0310657 Actn
FBtr0310658 Actn
FBtr0070345 Actn
FBtr0333802 Actn

18 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070345-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0070343-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0070344-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303048-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0310657-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0310658-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0310659-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333801-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333802-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070345-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070343-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070344-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303048-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0310657-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0310658-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0310659-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333801-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333802-3-prime-utr Drosophila melanogaster

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Other

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31166 NCBI Entrez Gene identifiers FBgn0000667
57710 BioGRID FBgn0000667

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1133.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 969.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1520.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1922.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1787.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 703.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 761.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1591.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1575.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1085.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1383.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1096.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 971.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 3232.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2186.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 831.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1642.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 599.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1898.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1056.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2272.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 436.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 937.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 642.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1204.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3062.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1863.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1519.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 964.0
FBgn0000667 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1094.0

25 Introns

DB identifier
Organism . Name
intron_FBgn0000667:19_FBgn0000667:15 Drosophila melanogaster
intron_FBgn0000667:15_FBgn0000667:12 Drosophila melanogaster
intron_FBgn0000667:12_FBgn0000667:11 Drosophila melanogaster
intron_FBgn0000667:11_FBgn0000667:10 Drosophila melanogaster
intron_FBgn0000667:10_FBgn0000667:7 Drosophila melanogaster
intron_FBgn0000667:7_FBgn0000667:6 Drosophila melanogaster
intron_FBgn0000667:6_FBgn0000667:5 Drosophila melanogaster
intron_FBgn0000667:5_FBgn0000667:3 Drosophila melanogaster
intron_FBgn0000667:3_FBgn0000667:2 Drosophila melanogaster
intron_FBgn0000667:11_FBgn0000667:8 Drosophila melanogaster
intron_FBgn0000667:8_FBgn0000667:7 Drosophila melanogaster
intron_FBgn0000667:5_FBgn0000667:4 Drosophila melanogaster
intron_FBgn0000667:4_FBgn0000667:3 Drosophila melanogaster
intron_FBgn0000667:3_FBgn0000667:1 Drosophila melanogaster
intron_FBgn0000667:18_FBgn0000667:15 Drosophila melanogaster
intron_FBgn0000667:11_FBgn0000667:9 Drosophila melanogaster
intron_FBgn0000667:9_FBgn0000667:7 Drosophila melanogaster
intron_FBgn0000667:19_FBgn0000667:14 Drosophila melanogaster
intron_FBgn0000667:14_FBgn0000667:12 Drosophila melanogaster
intron_FBgn0000667:17_FBgn0000667:15 Drosophila melanogaster
intron_FBgn0000667:17_FBgn0000667:14 Drosophila melanogaster
intron_FBgn0000667:17_FBgn0000667:16 Drosophila melanogaster
intron_FBgn0000667:16_FBgn0000667:12 Drosophila melanogaster
intron_FBgn0000667:17_FBgn0000667:13 Drosophila melanogaster
intron_FBgn0000667:13_FBgn0000667:12 Drosophila melanogaster

27 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Actn none 0.838444905   19067489
Lipid storage Actn none 0   19067489
Cell size and cell-cycle regulation (1) Actn none sp   16496002
C. trachomatis infection Actn C. trachomatis infection down np   18369471
P. aeruginosa infection Actn P. aeruginosa invasion decreased np   18369477
Muscle morphogenesis and function (1) Actn Lethal np   20220848
Muscle morphogenesis and function (1) Actn Lethal np   20220848
Muscle morphogenesis and function (1) Actn Lethal np   20220848
Muscle morphogenesis and function (3) Actn Split myofibril, fading Z-line np   20220848
Heat nociception (1) Actn Developmentally lethal 0   21074052
Heat nociception (1) Actn none -1.17   21074052
Heat nociception (1) Actn none -1.17   21074052
Heart development and function (1) Actn none 0.71   20371351
Serratia marcescens infection (1) Actn none 0.348484848484848   19520911
Notch pathway regulation (4) Actn none 0   19363474
Notch pathway regulation (4) Actn none 0   19363474
Notch pathway regulation (4) Actn Bristle morphology defects, notum malformation death sp   19363474
Muscle assembly and maintenance Actn Muscles spread, myosin filaments striated, actin filaments lack striation severe   18359903
Adiposity regulation (1) Actn none -0.135   20074523
RTK-Ras-ERK pathway regulation (1) Actn none -0.19 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Actn none -0.08 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Actn none -0.64 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Actn Increased ERK phosphorylation after sSpitz and EGF stimulation 1.94 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation Actn none -2.57   23263283
Muscle development and maintenance Actn Pupal lethal sp  
Muscle maintenance Actn Climbing defect sp  
Glycosylation regulation (1) Actn none sp   21203496

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