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Gene : RpS8 D. melanogaster

DB identifier  ? FBgn0039713 Secondary Identifier  ? CG7808
Name  ? Ribosomal protein S8 Source  FlyBase
  • synonyms:
  • FBgn0025277,
  • unnamed,
  • anon-EST:Liang-1.56,
  • FBgn0062869,
  • FBan0007808,
  • FBgn0025982,
  • CG7808,
  • Rps8,
  • Rp S8,
  • BcDNA:RH06886,
  • FBgn0062967,
  • S8,
  • BcDNA:SD17528,
  • FBgn0039713,
  • clone 1.56,
  • anon-fast-evolving-1A2,
  • anon-EST:fe1A2

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6 Alleles

DB identifier Symbol Allele Class Organism
FBal0286843 RpS8[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286844 RpS8[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0208396 RpS8[GD12288]   Drosophila melanogaster
FBal0216554 RpS8[DP01446]   Drosophila melanogaster
FBal0235894 RpS8[KK108882]   Drosophila melanogaster
FBal0275721 RpS8[NIG.7808R]   Drosophila melanogaster

796 Clones

Secondary Identifier DB identifier
EN01507 FBcl0325544
EN01543 FBcl0325545
EN02835 FBcl0325546
EN17053 FBcl0325554
EN17159 FBcl0325555
EN12861 FBcl0325556
CK01.81A.C2 FBcl0422837
CK01.69C.E6 FBcl0422932
542617 FBcl0422948
525056 FBcl0422953
525672 FBcl0422964
542567 FBcl0422984
528024 FBcl0422990
569257 FBcl0423021
524083 FBcl0423026
UUGC0309 FBcl0000083
AA433187 FBcl0000343
UUGC0755 FBcl0004263
EK249514 FBcl0007102
EK123906 FBcl0007168
EK116920 FBcl0007224
EK122953 FBcl0007256
EK055551 FBcl0007298
EK114157 FBcl0007304
EK261658 FBcl0007334
EK195434 FBcl0007350
EK241459 FBcl0007374
EK254336 FBcl0007382
EK238410 FBcl0007392
EK062641 FBcl0007404

5 Exons

DB identifier Symbol
FBgn0039713:1 RpS8:1
FBgn0039713:2 RpS8:2
FBgn0039713:3 RpS8:3
FBgn0039713:5 RpS8:5
FBgn0039713:4 RpS8:4

2 Transcripts

DB identifier Gene
FBtr0085489 RpS8
FBtr0310274 RpS8

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0085489-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0310274-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085489-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0310274-3-prime-utr Drosophila melanogaster

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52 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
43532 NCBI Entrez Gene identifiers FBgn0039713
68391 BioGRID FBgn0039713

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 18593.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 5767.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 20152.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 24651.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 13829.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 27316.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 11944.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 28451.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 29033.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 14038.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 16089.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 24557.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 14747.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 19712.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 25291.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 20100.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 15543.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 14979.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 21711.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 13186.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 19707.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 12728.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 10096.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 9008.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 9203.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 14281.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 14219.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 14287.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 11004.0
FBgn0039713 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 15174.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0039713:1_FBgn0039713:2 Drosophila melanogaster
intron_FBgn0039713:2_FBgn0039713:3 Drosophila melanogaster
intron_FBgn0039713:3_FBgn0039713:4 Drosophila melanogaster
intron_FBgn0039713:3_FBgn0039713:5 Drosophila melanogaster

36 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation RpS8 none -2.72   19216764
Lipid storage RpS8 none 2.907583587   19067489
Lipid storage RpS8 none 0.457021505   19067489
Drosophila C virus infection RpS8 Drosophila C virus replication down np   17040126
Cytokinesis regulation RpS8 Binucleate cells with decreased viability medium   15547975
Drosophila C virus infection RpS8 Drosophila C virus infection reduced np   15713840
Constitutive protein secretion and Golgi organization (1) RpS8 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) RpS8 Increased G1 DNA content, decreased G2 DNA content, decreased viability, decreased cytokinesis sp   16496002
Cell size and cell-cycle regulation (1) RpS8 Increased G1 DNA content, decreased G2 DNA content, decreased viability, decreased cytokinesis sp   16496002
Cell size and cell-cycle regulation (2) RpS8 Decreased viability 0.89   16496002
Cell size and cell-cycle regulation (2) RpS8 Decreased viability 0.913   16496002
Cell size and cell-cycle regulation (3) RpS8 Decreased cell number 381   16496002
Cell size and cell-cycle regulation (3) RpS8 Decreased cell number 404   16496002
Cell size and cell-cycle regulation (4) RpS8 Increased number of mitotic cells 0.6   16496002
Cell size and cell-cycle regulation (4) RpS8 none below threshold   16496002
Candida albicans phagocytosis (1) RpS8 none np   16336044
Lipid storage RpS8 More dispersed droplets strong (but ribosomal)   18408709
Combinatorial effect with methyl methanesulphonate (2) RpS8 Synthetic lethal with methyl methanesulphonate sp   19543366
Mutant human huntingtin aggregation RpS8 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) RpS8 Lethal np   20220848
Muscle morphogenesis and function (1) RpS8 Lethal np   20220848
Muscle morphogenesis and function (2) RpS8 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Muscle morphogenesis and function (3) RpS8 none np   20220848
Heat nociception (1) RpS8 none -1.17   21074052
Heart development and function (1) RpS8 none 1   20371351
Serratia marcescens infection (1) RpS8 none 1.07894736842105   19520911
Notch pathway regulation (4) RpS8 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) RpS8 Completely lethal (before pupal) sp   19363474
PGN-induced dJNK phosphorylation RpS8 Increased P-JNK protein expression with PGN 3.23 15 min PGN induction 19893628
Self-renewal and differentiation in neural stem cells RpS8 Neuroblast smaller cell size, neuroblast less large cells, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with smaller neuroblast cell size, neuroblasts smaller, neuroblast underproliferation, lethal sp   21549331

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