modENCODE |  Help |  blog

Gene : lwr D. melanogaster

DB identifier  ? FBgn0010602 Secondary Identifier  ? CG3018
Name  ? lesswright Source  FlyBase
  • synonyms:
  • l(2)05487,
  • l(2)01519,
  • DUbc9,
  • FBgn0010602,
  • FBgn0015755,
  • l(2)02858,
  • FBan0003018,
  • Lwr,
  • semi,
  • DmUbc9,
  • dip4,
  • FBgn0022761,
  • FBgn0010523,
  • hbl,
  • i56,
  • Ubc 9,
  • unnamed,
  • semushi,
  • CG3018,
  • Ubiquitin conjugating enzyme 9,
  • ubiquitin-conjugating enzyme 9,
  • UBC9,
  • Iwr,
  • Lesswright,
  • Ubc-9,
  • l(2)05486,
  • hunchback-like,
  • i105

Sequence Feature Displayer

Publication Counts Displayer

Genomics

Gene Ontology Displayer

Homologue Displayer

Mod Mine G Browse Displayer

Overlapping Features Displayer

Regulatory Regions Displayer

28 Alleles

DB identifier Symbol Allele Class Organism
FBal0266323 lwr[GL00624]   Drosophila melanogaster
FBal0179001 lwr[DG29707]   Drosophila melanogaster
FBal0245658 lwr[JF01386]   Drosophila melanogaster
FBal0008009 lwr[02858]   Drosophila melanogaster
FBal0178999 lwr[e02021]   Drosophila melanogaster
FBal0008090 lwr[05486] loss of function allele, hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0101271 lwr[01519a]   Drosophila melanogaster
FBal0122954 lwr[semi710]   Drosophila melanogaster
FBal0122957 lwr[4-3] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0266555 lwr[HMS01648]   Drosophila melanogaster
FBal0095295 lwr[unspecified]   Drosophila melanogaster
FBal0093851 lwr[+LD12093]   Drosophila melanogaster
FBal0093850 lwr[107]   Drosophila melanogaster
FBal0179002 lwr[+t2.4]   Drosophila melanogaster
FBal0093849 lwr[118]   Drosophila melanogaster
FBal0189967 lwr[13] loss of function allele Drosophila melanogaster
FBal0190054 lwr[GS-A2612]   Drosophila melanogaster
FBal0122958 lwr[14] loss of function allele Drosophila melanogaster
FBal0190876 lwr[10] loss of function allele Drosophila melanogaster
FBal0103666 lwr[Act5C.PB]   Drosophila melanogaster
FBal0122956 lwr[5] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0103665 lwr[Act5C.T:Ivir\HA1]   Drosophila melanogaster
FBal0179000 lwr[DN.Scer\UAS]   Drosophila melanogaster
FBal0158993 lwr[MtnA.T:Ivir\HA1]   Drosophila melanogaster
FBal0122955 lwr[Scer\UAS.cAa]   Drosophila melanogaster
FBal0193526 lwr[Scer\UAS.C]   Drosophila melanogaster
FBal0209954 lwr[GD10017]   Drosophila melanogaster
FBal0235157 lwr[KK107780]   Drosophila melanogaster

62 Clones

Secondary Identifier DB identifier
DPiM_GM08377 FBcl0741235
UUGC1037 FBcl0005567
EK162706 FBcl0068768
EK102222 FBcl0069058
EK102246 FBcl0069112
EK271141 FBcl0069150
EK047806 FBcl0070880
EK189307 FBcl0071476
EK121853 FBcl0071550
EK138339 FBcl0071590
EK174628 FBcl0071648
EN07112 FBcl0090881
EN09714 FBcl0090897
GH26539 FBcl0116931
GH02236 FBcl0116941
GM02171 FBcl0137459
GM08377 FBcl0137565
GM10219 FBcl0137571
GM08125 FBcl0137573
GM09043 FBcl0137575
GM08117 FBcl0137577
GM13641 FBcl0143986
GM23783 FBcl0143987
LD06144 FBcl0156044
LD07405 FBcl0156154
LD12093 FBcl0156169
LD40256 FBcl0169649
LD41696 FBcl0169660
LD22390 FBcl0169661
LD40254 FBcl0169662

6 Exons

DB identifier Symbol
FBgn0010602:6 lwr:6
FBgn0010602:3 lwr:3
FBgn0010602:5 lwr:5
FBgn0010602:1 lwr:1
FBgn0010602:4 lwr:4
FBgn0010602:2 lwr:2

4 Transcripts

DB identifier Gene
FBtr0310029 lwr
FBtr0310028 lwr
FBtr0078082 lwr
FBtr0078081 lwr

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0078081-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0078082-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0310028-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0310029-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078081-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078082-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0310028-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0310029-3-prime-utr Drosophila melanogaster

Interactions

Cytoscape Network Displayer

 

Other

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
33226 NCBI Entrez Gene identifiers FBgn0010602
59482 BioGRID FBgn0010602

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3410.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 3483.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2604.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 4689.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 4455.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 5377.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1721.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2315.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1341.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3203.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2694.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2416.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2789.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 4364.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2866.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2038.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2338.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2527.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 3217.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2063.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2149.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2609.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2001.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2014.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1244.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2924.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2998.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2941.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2268.0
FBgn0010602 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2484.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0010602:6_FBgn0010602:3 Drosophila melanogaster
intron_FBgn0010602:6_FBgn0010602:5 Drosophila melanogaster
intron_FBgn0010602:5_FBgn0010602:1 Drosophila melanogaster
intron_FBgn0010602:6_FBgn0010602:4 Drosophila melanogaster
intron_FBgn0010602:6_FBgn0010602:2 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage lwr none -0.108884963   19067489
Lipid storage lwr none 0.699883356   19067489
Cell size and cell-cycle regulation (1) lwr none sp   16496002
Cell size and cell-cycle regulation (1) lwr none sp   16496002
Lipid storage lwr Smaller sized lipid droplets, more dispersed moderate   18408709
Muscle morphogenesis and function (1) lwr Lethal np   20220848
Muscle morphogenesis and function (1) lwr none np   20220848
Muscle morphogenesis and function (2) lwr Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) lwr none -0.82   21074052
Heart development and function (1) lwr none 1   20371351
Serratia marcescens infection (1) lwr none 0.576923076923076   19520911
Notch pathway regulation (4) lwr Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) lwr Completely lethal (pupal) sp   19363474
G2-M DNA damage checkpoint regulation (2) lwr Increased histone H3 phosphorylation with doxorubicin 20.12 with doxorubicin 21205937
G2-M DNA damage checkpoint regulation (2) lwr none 11.9 with etoposide 21205937
G2-M DNA damage checkpoint regulation (2) lwr none 31 X-ray exposure 21205937
G2-M DNA damage checkpoint regulation (2) lwr none 13.19 with bleocin 21205937
Pol II elongation lwr none 86 20 min heat shock 19279664
Adiposity regulation (1) lwr none 0.103   20074523
RTK-Ras-ERK pathway regulation (1) lwr Increased ERK phosphorylation after EGF stimulation 1.69 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) lwr none -0.07 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) lwr none -0.53 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) lwr none 0.96 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation lwr none -1.88   23263283
Glycosylation regulation (4) lwr none sp   21203496
Huntingtin (Htt) aggregates formation lwr Decreased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

0 Submissions