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Gene : Cka D. melanogaster

DB identifier  ? FBgn0044323 Secondary Identifier  ? CG7392
Name  ? Connector of kinase to AP-1 Source  FlyBase
  • synonyms:
  • FBgn0044323,
  • Dcka,
  • CG7392,
  • anon-WO0172774.174,
  • 5836,
  • FBgn0046425,
  • connector of kinase to AP-1,
  • anon-WO0172774.179,
  • FBgn0010681,
  • WD-40-family-member,
  • l(2)05836,
  • FBgn0031978,
  • FBan0007392,
  • l(2)s1883,
  • CKA,
  • FBgn0026012,
  • FBgn0046426,
  • FBgn0010608,
  • anon-WO0172774.177,
  • FBgn0046423,
  • anon-WO0172774.175,
  • FBgn0046427

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17 Alleles

DB identifier Symbol Allele Class Organism
FBal0240267 Cka[HM05138]   Drosophila melanogaster
FBal0184328 Cka[DG29705]   Drosophila melanogaster
FBal0245698 Cka[JF01432]   Drosophila melanogaster
FBal0160692 Cka[EY10818]   Drosophila melanogaster
FBal0064704 Cka[k12606]   Drosophila melanogaster
FBal0064705 Cka[k12603]   Drosophila melanogaster
FBal0119329 Cka[EP2514]   Drosophila melanogaster
FBal0008096 Cka[05836]   Drosophila melanogaster
FBal0009303 Cka[s1883]   Drosophila melanogaster
FBal0284759 Cka[c305a]   Drosophila melanogaster
FBal0184327 Cka[hs.PC]   Drosophila melanogaster
FBal0184330 Cka[3]   Drosophila melanogaster
FBal0184331 Cka[2]   Drosophila melanogaster
FBal0184329 Cka[4]   Drosophila melanogaster
FBal0263087 Cka[HMS00081]   Drosophila melanogaster
FBal0206587 Cka[GD12225]   Drosophila melanogaster
FBal0230688 Cka[KK100338]   Drosophila melanogaster

335 Clones

Secondary Identifier DB identifier
62853 FBcl0401513
EK042626 FBcl0001612
EK232057 FBcl0001698
EK152329 FBcl0001866
EK246054 FBcl0001994
EK305164 FBcl0002656
EK061730 FBcl0002810
EK233050 FBcl0003014
AT08055 FBcl0014763
AT10327 FBcl0014779
AT19215 FBcl0014791
AT17688 FBcl0014795
AT28323 FBcl0014805
AT20378 FBcl0014809
AT28544 FBcl0014841
AT10015 FBcl0014845
AT19937 FBcl0014857
EK292038 FBcl0047672
EK146835 FBcl0047684
bs57e04 FBcl0049171
EN09519 FBcl0093323
EN11524 FBcl0093351
GH05516 FBcl0121831
GH08487 FBcl0121835
GH03445 FBcl0121865
EK300035 FBcl0138956
GM01563 FBcl0139505
GM02877 FBcl0139519
EK188514 FBcl0140118
EK296039 FBcl0140682

14 Exons

DB identifier Symbol
FBgn0044323:4 Cka:4
FBgn0044323:6 Cka:6
FBgn0044323:7 Cka:7
FBgn0044323:8 Cka:8
FBgn0044323:11 Cka:11
FBgn0044323:14 Cka:14
FBgn0044323:1 Cka:1
FBgn0044323:10 Cka:10
FBgn0044323:12 Cka:12
FBgn0044323:3 Cka:3
FBgn0044323:13 Cka:13
FBgn0044323:2 Cka:2
FBgn0044323:5 Cka:5
FBgn0044323:9 Cka:9

7 Transcripts

DB identifier Gene
FBtr0079536 Cka
FBtr0306001 Cka
FBtr0306000 Cka
FBtr0079539 Cka
FBtr0079537 Cka
FBtr0079538 Cka
FBtr0333096 Cka

14 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0079536-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0079537-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0079538-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0079539-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0306000-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0306001-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333096-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079536-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079537-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079538-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079539-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0306000-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0306001-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333096-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34096 NCBI Entrez Gene identifiers FBgn0044323
60230 BioGRID FBgn0044323

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 840.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 949.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 723.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 741.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 742.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 495.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 968.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 975.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 725.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1250.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1254.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 874.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 726.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1417.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1154.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 878.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 999.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1058.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1145.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 881.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 954.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 846.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 460.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 854.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 692.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1474.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1427.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1400.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1101.0
FBgn0044323 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1135.0

15 Introns

DB identifier
Organism . Name
intron_FBgn0044323:3_FBgn0044323:6 Drosophila melanogaster
intron_FBgn0044323:6_FBgn0044323:7 Drosophila melanogaster
intron_FBgn0044323:7_FBgn0044323:8 Drosophila melanogaster
intron_FBgn0044323:8_FBgn0044323:13 Drosophila melanogaster
intron_FBgn0044323:4_FBgn0044323:6 Drosophila melanogaster
intron_FBgn0044323:8_FBgn0044323:11 Drosophila melanogaster
intron_FBgn0044323:11_FBgn0044323:14 Drosophila melanogaster
intron_FBgn0044323:1_FBgn0044323:6 Drosophila melanogaster
intron_FBgn0044323:8_FBgn0044323:14 Drosophila melanogaster
intron_FBgn0044323:8_FBgn0044323:10 Drosophila melanogaster
intron_FBgn0044323:10_FBgn0044323:12 Drosophila melanogaster
intron_FBgn0044323:2_FBgn0044323:6 Drosophila melanogaster
intron_FBgn0044323:5_FBgn0044323:6 Drosophila melanogaster
intron_FBgn0044323:7_FBgn0044323:9 Drosophila melanogaster
intron_FBgn0044323:9_FBgn0044323:12 Drosophila melanogaster

33 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Cka none 0.22858746   19067489
Lipid storage Cka none 0.694726926   19067489
Lipid storage Cka none 0.015745583   19067489
Lipid storage Cka none -1.000964276   19067489
ERK signaling Cka ERK activation reduced weak   17086199
L. monocytogenes infection Cka Fewer infected cells ****   16157870
Cell size and cell-cycle regulation (1) Cka none sp   16496002
Candida albicans phagocytosis (1) Cka Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) Cka Decreased Escherichia coli phagocytosis 38   16336044
Candida albicans phagocytosis (3) Cka none 45   16336044
Mutant human huntingtin aggregation Cka Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Cka Lethal np   20220848
Muscle morphogenesis and function (1) Cka Lethal np   20220848
Muscle morphogenesis and function (2) Cka Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) Cka none -1.17   21074052
Heat nociception (1) Cka Developmentally lethal -1.17   21074052
Heart development and function (1) Cka none 0.9   20371351
Heart development and function (1) Cka none 1   20371351
Heart development and function (2) Cka Decreased viability 3.59   20371351
Serratia marcescens infection (1) Cka none -0.705128205128205   19520911
Notch pathway regulation (4) Cka Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Cka Completely lethal (pupal) sp   19363474
PGN-induced dJNK phosphorylation Cka Increased P-JNK protein expression with PGN 7.7 15 min PGN induction 19893628
PGN-induced dJNK phosphorylation Cka Increased P-JNK protein expression with PGN 7.2 60 min PGN induction 19893628
Adiposity regulation (1) Cka none -0.066   20074523
S2 cell spreading Cka none np   21041442
RTK-Ras-ERK pathway regulation (1) Cka none 0 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Cka none -0.03 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Cka none -0.16 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Cka none 0.41 10 minutes sSpitz stimulation 22028469

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