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Gene : phl D. melanogaster

DB identifier  ? FBgn0003079 Secondary Identifier  ? CG2845
Name  ? pole hole Source  FlyBase
  • synonyms:
  • DRaf1,
  • D-RAF,
  • Pole Hole,
  • l(1)G0475,
  • Raf1,
  • l(1)polehole,
  • l(1)2Fe,
  • D-raf1,
  • l(1)pole hole,
  • DRaf,
  • ph,
  • FBgn0040149,
  • rafl,
  • Phl,
  • ph1,
  • l(1)ph,
  • l(1)polehole/draf,
  • Raf/phl,
  • l(1)phl,
  • pole-hole,
  • lincRNA.937,
  • FBan0002845,
  • Draf-1,
  • l(1)raf,
  • Polehole,
  • RAF,
  • CG2845,
  • C110,
  • raf-1,
  • FBgn0003079,
  • raf-like-oncogene-1,
  • 11-29,
  • EG:BACH48C10.3

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100 Alleles

DB identifier Symbol Allele Class Organism
FBal0282811 phl[RBD+CRD.Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0282812 phl[DN.Scer\UAS.cUa]   Drosophila melanogaster
FBal0245477 phl[JF01185]   Drosophila melanogaster
FBal0246433 phl[fl.Scer\UAS]   Drosophila melanogaster
FBal0245747 phl[JF01483]   Drosophila melanogaster
FBal0248864 phl[VDRC.cUa]   Drosophila melanogaster
FBal0196856 phl[Adh3'UTR.MtnA.T:PV\Pym]   Drosophila melanogaster
FBal0196857 phl[KM.MtnA.T:PV\Pym]   Drosophila melanogaster
FBal0196858 phl[RBDmut.MtnA.T:PV\Pym]   Drosophila melanogaster
FBal0196859 phl[CRDmut.MtnA.T:PV\Pym]   Drosophila melanogaster
FBal0196860 phl[S346A.MtnA.T:PV\Pym]   Drosophila melanogaster
FBal0196861 phl[AL.AA.MtnA.T:PV\Pym] loss of function allele Drosophila melanogaster
FBal0196862 phl[AL.ED.MtnA.T:PV\Pym]   Drosophila melanogaster
FBal0196863 phl[RBDmut.AL.ED.MtnA.T:PV\Pym]   Drosophila melanogaster
FBal0257035 phl[NIG.2845R]   Drosophila melanogaster
FBal0103720 phl[G0475]   Drosophila melanogaster
FBal0278625 phl[GL01125]   Drosophila melanogaster
FBal0266213 phl[K498S.MtnA.T:Mmus\Fkbp,T:PV\Pym,T:Myr-Src64B]   Drosophila melanogaster
FBal0134038 phl[MtnA.T:Mmus\Fkbp,T:PV\Pym,T:Myr-Src64B]   Drosophila melanogaster
FBal0134039 phl[MtnA.T:Mmus\Fkbp,T:PV\Pym,T:Myr-Src64B-GA]   Drosophila melanogaster
FBal0285341 phl[98]   Drosophila melanogaster
FBal0287810 phl[hs.PU]   Drosophila melanogaster
FBal0050261 phl[cBa]   Drosophila melanogaster
FBal0039752 phl[F22.hs] heat sensitive gain of function allele Drosophila melanogaster
FBal0044248 phl[C20]   Drosophila melanogaster
FBal0050254 phl[Delta370]   Drosophila melanogaster
FBal0032421 phl[hs.sev]   Drosophila melanogaster
FBal0050262 phl[hs.PD]   Drosophila melanogaster
FBal0013770 phl[2]   Drosophila melanogaster
FBal0060946 phl[hs.2sev]   Drosophila melanogaster

67 Clones

Secondary Identifier DB identifier
DPiM_GH03557 FBcl0741591
EC39614 FBcl0060925
EK254745 FBcl0066400
EK065314 FBcl0066430
EK260360 FBcl0066458
EK208826 FBcl0066476
EK193037 FBcl0066488
EK304752 FBcl0066524
EK292137 FBcl0066532
EK170907 FBcl0066558
EK055418 FBcl0066566
EK190711 FBcl0066650
EK156162 FBcl0066658
EK061607 FBcl0066670
EK197501 FBcl0066692
EK130704 FBcl0066726
EK052959 FBcl0066738
EK130015 FBcl0066748
EK053208 FBcl0066756
EP03957 FBcl0074013
EP11532 FBcl0074025
EP07561 FBcl0074039
EP06726 FBcl0074151
EP08645 FBcl0074221
EP07926 FBcl0074341
GH03557 FBcl0125577
LP13362 FBcl0187627
RE56023 FBcl0223669
RE58469 FBcl0223671
RE04747 FBcl0223785

8 Exons

DB identifier Symbol
FBgn0003079:4 phl:4
FBgn0003079:5 phl:5
FBgn0003079:6 phl:6
FBgn0003079:7 phl:7
FBgn0003079:8 phl:8
FBgn0003079:1 phl:1
FBgn0003079:2 phl:2
FBgn0003079:3 phl:3

2 Transcripts

DB identifier Gene
FBtr0070401 phl
FBtr0344007 phl

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070401-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0344007-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070401-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0344007-3-prime-utr Drosophila melanogaster

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83 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31221 NCBI Entrez Gene identifiers FBgn0003079
57758 BioGRID FBgn0003079

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 454.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 877.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1159.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1070.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 888.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 291.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1050.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1002.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 621.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1115.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1133.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 470.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 844.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 639.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1188.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 640.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 858.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 317.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 680.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 748.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1696.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 788.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 621.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1296.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 574.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3384.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2009.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2411.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1564.0
FBgn0003079 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1283.0

7 Introns

DB identifier
Organism . Name
intron_FBgn0003079:4_FBgn0003079:5 Drosophila melanogaster
intron_FBgn0003079:5_FBgn0003079:6 Drosophila melanogaster
intron_FBgn0003079:6_FBgn0003079:7 Drosophila melanogaster
intron_FBgn0003079:7_FBgn0003079:8 Drosophila melanogaster
intron_FBgn0003079:1_FBgn0003079:2 Drosophila melanogaster
intron_FBgn0003079:2_FBgn0003079:3 Drosophila melanogaster
intron_FBgn0003079:3_FBgn0003079:5 Drosophila melanogaster

39 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation phl none -0.62   19216764
Lipid storage phl none 0.72773975   19067489
Lipid storage phl none 1.894724382   19067489
Lipid storage phl none 0.168556943   19067489
Lipid storage phl none 0.151108462   19067489
ERK signaling phl ERK activation reduced strong   17086199
Cell cycle regulation (1) phl none np   15616552
Cell cycle regulation (2) phl none np   15616552
Cell size and cell-cycle regulation (1) phl none sp   16496002
Cell size and cell-cycle regulation (1) phl none sp   16496002
Cell size and cell-cycle regulation (1) phl none sp   16496002
NFAT signaling phl Decreased NFAT translocation 1   16511445
Muscle morphogenesis and function (1) phl none np   20220848
Heat nociception (1) phl none 0.22   21074052
Heart development and function (1) phl none 1   20371351
Serratia marcescens infection (1) phl none 0.409523809523809   19520911
Notch pathway regulation (4) phl Colour defects, notum malformation death sp   19363474
Notch pathway regulation (1) phl Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) phl none np en-GAL4 20493818
Notch pathway regulation (2) phl none np en-GAL4 20493818
Notch pathway regulation (2) phl Upregulation of Notch pathway; wing disc size: overgrown; wing disc NRE:EGFP: up, broader; wing disc myrRFP: accumulation; lethal sp en-GAL4 20493818
Notch pathway regulation (3) phl none np   20493818
Adiposity regulation (1) phl none -0.438   20074523
Blood cell homeostasis regulation (1) phl none np   20540764
Blood cell homeostasis regulation (2) phl none np   20540764
Actin organization and cell morphology (1) phl none np   19265526
Actin organization and cell morphology (2) phl Altered cell morphology np   19265526
Actin organization and cell morphology (3) phl none np   19265526
Actin organization and cell morphology (4) phl Altered cell morphology np   19265526
Actin organization and cell morphology (5) phl Altered cell morphology np   19265526

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