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Gene : zfh1 D. melanogaster

DB identifier  ? FBgn0004606 Secondary Identifier  ? CG1322
Name  ? Zn finger homeodomain 1 Source  FlyBase
  • synonyms:
  • zinc finger homeodomain protein-1,
  • ZFH1,
  • zinc-finger homeodomain1,
  • Zinc-finger homeodomain protein 1,
  • FBan0001322,
  • zfl-1,
  • Zinc Finger Homeodomain 1,
  • FBgn0004606,
  • CG1322,
  • zinc finger homeodomain-1,
  • zhf1,
  • zinc-finger homeobox gene,
  • ZFH-1,
  • Zn homeodomain 1,
  • Zfh1a,
  • FBgn0010733,
  • l(3)00865

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39 Alleles

DB identifier Symbol Allele Class Organism
FBal0281242 zfh1[GL01539]   Drosophila melanogaster
FBal0009394 zfh1[00865]   Drosophila melanogaster
FBal0278621 zfh1[GL01066]   Drosophila melanogaster
FBal0242191 zfh1[JF02509]   Drosophila melanogaster
FBal0217714 zfh1[MB07519]   Drosophila melanogaster
FBal0033231 zfh1[5] loss of function allele Drosophila melanogaster
FBal0033220 zfh1[10] loss of function allele Drosophila melanogaster
FBal0033234 zfh1[8] loss of function allele Drosophila melanogaster
FBal0046892 zfh1[hs.PL]   Drosophila melanogaster
FBal0033235 zfh1[9] loss of function allele Drosophila melanogaster
FBal0033222 zfh1[12] loss of function allele Drosophila melanogaster
FBal0033233 zfh1[7] loss of function allele Drosophila melanogaster
FBal0033224 zfh1[14] loss of function allele Drosophila melanogaster
FBal0154338 zfh1[dsRNA.cKa]   Drosophila melanogaster
FBal0033232 zfh1[6] loss of function allele Drosophila melanogaster
FBal0086259 zfh1[unspecified]   Drosophila melanogaster
FBal0086261 zfh1[65.34] amorphic allele - molecular evidence, amorphic allele - genetic evidence Drosophila melanogaster
FBal0033226 zfh1[16] loss of function allele Drosophila melanogaster
FBal0154337 zfh1[dsRNA.si.cKa]   Drosophila melanogaster
FBal0033221 zfh1[11] loss of function allele Drosophila melanogaster
FBal0033225 zfh1[15] loss of function allele Drosophila melanogaster
FBal0033229 zfh1[3] loss of function allele Drosophila melanogaster
FBal0033228 zfh1[2] loss of function allele, amorphic allele - genetic evidence Drosophila melanogaster
FBal0086260 zfh1[75.26] amorphic allele - molecular evidence, amorphic allele - genetic evidence Drosophila melanogaster
FBal0033227 zfh1[1] loss of function allele Drosophila melanogaster
FBal0033223 zfh1[13] loss of function allele Drosophila melanogaster
FBal0033230 zfh1[4] loss of function allele Drosophila melanogaster
FBal0101101 zfh1[Act5C.PP]   Drosophila melanogaster
FBal0140831 zfh1[DeltaHD.Scer\UAS]   Drosophila melanogaster
FBal0140830 zfh1[CIDm.Scer\UAS]   Drosophila melanogaster

111 Clones

Secondary Identifier DB identifier
EK306436 FBcl0001870
EK228845 FBcl0001912
AT04881 FBcl0038377
AT12749 FBcl0038459
EN05918 FBcl0100035
EN03016 FBcl0100261
EN02801 FBcl0100431
EN06042 FBcl0100487
EN13040 FBcl0100505
EN09054 FBcl0100513
EN07641 FBcl0100533
EN02828 FBcl0100535
EN17146 FBcl0100545
EN03623 FBcl0100547
EN03952 FBcl0100549
EN09553 FBcl0100557
EN17249 FBcl0100559
EN05835 FBcl0100561
EN11547 FBcl0100569
EN16722 FBcl0100573
EN06710 FBcl0100751
EN01338 FBcl0100753
EK159735 FBcl0138406
EK132554 FBcl0138540
EK241127 FBcl0138618
EK197505 FBcl0138640
EK249355 FBcl0138668
EK256811 FBcl0138680
EK254342 FBcl0138690
EK133520 FBcl0138750

7 Exons

DB identifier Symbol
FBgn0004606:1 zfh1:1
FBgn0004606:2 zfh1:2
FBgn0004606:3 zfh1:3
FBgn0004606:7 zfh1:7
FBgn0004606:4 zfh1:4
FBgn0004606:5 zfh1:5
FBgn0004606:6 zfh1:6

3 Transcripts

DB identifier Gene
FBtr0331180 zfh1
FBtr0085701 zfh1
FBtr0085702 zfh1

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0331180-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085702-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085701-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0331180-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085702-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085701-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
43650 NCBI Entrez Gene identifiers FBgn0004606
68501 BioGRID FBgn0004606

12 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  
Fly Transcription Factor/microRNA Regulatory Network  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2833.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2036.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 3388.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 3576.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 5319.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2401.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3898.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 7486.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 4848.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3472.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 3754.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 3233.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 4035.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 3257.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 4273.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2815.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 4345.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 4305.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1757.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2434.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 5261.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2050.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2788.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 4826.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2966.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 986.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 834.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2083.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1065.0
FBgn0004606 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2013.0

6 Introns

DB identifier
Organism . Name
intron_FBgn0004606:1_FBgn0004606:2 Drosophila melanogaster
intron_FBgn0004606:2_FBgn0004606:3 Drosophila melanogaster
intron_FBgn0004606:3_FBgn0004606:5 Drosophila melanogaster
intron_FBgn0004606:5_FBgn0004606:7 Drosophila melanogaster
intron_FBgn0004606:4_FBgn0004606:5 Drosophila melanogaster
intron_FBgn0004606:5_FBgn0004606:6 Drosophila melanogaster

39 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage zfh1 none 2.465642305   19067489
Lipid storage zfh1 none 0.015041818   19067489
Lipid storage zfh1 none 0.915248989   19067489
Lipid storage zfh1 none 0   19067489
Neural outgrowth zfh1 Defasciculation np   18604272
ERK signaling zfh1 ERK activation reduced strong   17086199
Intracellular Listeria monocytogenes infection zfh1 Decreased GFP protein expression moderate   16020693
Innate immunity zfh1 Increased IMD reporter activity np   16163390
Hedgehog signaling zfh1 Increased Hedgehog reporter activity 3.27   16311596
Cell size and cell-cycle regulation (1) zfh1 none sp   16496002
Heart development and function zfh1 Heart tube assembly defects, heart patterning defects np   14684833
Ca2+ channel regulation zfh1 Decreased Ca2+ influx 4   16645049
Dendrite pattern formation zfh1 none np   16547170
Muscle morphogenesis and function (1) zfh1 none np   20220848
Muscle morphogenesis and function (1) zfh1 none np   20220848
Heat nociception (1) zfh1 none -0.93   21074052
Heat nociception (1) zfh1 Developmentally lethal 0   21074052
Heart development and function (1) zfh1 none 1   20371351
Serratia marcescens infection (1) zfh1 none 1   19520911
Serratia marcescens infection (1) zfh1 none 0.376068376068376   19520911
Notch pathway regulation (4) zfh1 none 0   19363474
Notch pathway regulation (4) zfh1 none 0   19363474
Hh pathway regulation zfh1 Upregulation of Hh pathway 0.500654653137327   17903264
Hh pathway regulation zfh1 Upregulation of Hh pathway 0.660072361550401   17903264
Notch pathway regulation (1) zfh1 Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) zfh1 Lethal very strong en-GAL4 20493818
Notch pathway regulation (2) zfh1 none np C96-GAL4 20493818
Notch pathway regulation (2) zfh1 Adult wing veins: disrupted, thinner sp en-GAL4 20493818
Notch pathway regulation (2) zfh1 Upregulation of Notch pathway; wing disc NRE:EGFP: up sp en-GAL4 20493818
Notch pathway regulation (3) zfh1 none np   20493818

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