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Gene : Rpn11 D. melanogaster

DB identifier  ? FBgn0028694 Secondary Identifier  ? CG18174
Name  ? Regulatory particle non-ATPase 11 Source  FlyBase
  • synonyms:
  • p37B,
  • DmS13,
  • 37B,
  • FBan0018174,
  • yippee interacting protein 5,
  • S13,
  • CG18174,
  • FBgn0028694,
  • RPN11,
  • yip5

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9 Alleles

DB identifier Symbol Allele Class Organism
FBal0257103 Rpn11[HMS00071]   Drosophila melanogaster
FBal0181776 Rpn11[f00396]   Drosophila melanogaster
FBal0161728 Rpn11[f00386]   Drosophila melanogaster
FBal0155939 Rpn11[BG01694]   Drosophila melanogaster
FBal0286835 Rpn11[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286836 Rpn11[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0208407 Rpn11[GD8888]   Drosophila melanogaster
FBal0222838 Rpn11[d07228]   Drosophila melanogaster
FBal0272808 Rpn11[NIG.18174R]   Drosophila melanogaster

45 Clones

Secondary Identifier DB identifier
EK111326 FBcl0033672
ESG014a.E21_D08 FBcl0009237
EK212537 FBcl0032872
EK256537 FBcl0033376
EK057421 FBcl0033384
EK186551 FBcl0033396
AT12101 FBcl0041469
bs75a04 FBcl0057447
CK01641 FBcl0060513
CK00507 FBcl0060517
EP05326 FBcl0088557
EN10727 FBcl0101319
GH11324 FBcl0130763
GH11304 FBcl0130785
GH22356 FBcl0130945
GH06665 FBcl0132055
GH06069 FBcl0132059
GH12392 FBcl0132067
GM19944 FBcl0148161
GM15832 FBcl0148167
LD43366 FBcl0176655
LD34816 FBcl0177079
LP19756 FBcl0190084
LP02542 FBcl0190144
RE07158 FBcl0233043
RE10181 FBcl0233155
RE07468 FBcl0233158
RE19901 FBcl0233162
RE55995 FBcl0233165
RE38188 FBcl0233297

3 Exons

DB identifier Symbol
FBgn0028694:3 Rpn11:3
FBgn0028694:2 Rpn11:2
FBgn0028694:1 Rpn11:1

1 Transcripts

DB identifier Gene
FBtr0079027 Rpn11

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0079027-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079027-3-prime-utr Drosophila melanogaster

Interactions

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Other

74 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
33738 NCBI Entrez Gene identifiers FBgn0028694
59913 BioGRID FBgn0028694

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1513.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2076.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1851.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1948.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1461.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1151.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1579.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1376.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 905.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2628.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1515.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 829.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1362.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1659.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1959.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1360.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1458.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1795.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2321.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1500.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1460.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1816.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1463.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1682.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1146.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3682.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 642.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1177.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1062.0
FBgn0028694 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1014.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0028694:3_FBgn0028694:2 Drosophila melanogaster
intron_FBgn0028694:2_FBgn0028694:1 Drosophila melanogaster

33 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Rpn11 none -0.374140606   19067489
Lipid storage Rpn11 none 1.842672883   19067489
ERK signaling Rpn11 ERK activation reduced weak   17086199
Intracellular Listeria monocytogenes infection Rpn11 Decreased GFP protein expression moderate   16020693
Hedgehog signaling Rpn11 Decreased Hedgehog reporter activity -2.82   16311596
Constitutive protein secretion and Golgi organization (1) Rpn11 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Rpn11 Decreased viability sp   16496002
Cell size and cell-cycle regulation (2) Rpn11 Decreased viability 0.911   16496002
Cell size and cell-cycle regulation (3) Rpn11 none 481   16496002
Candida albicans phagocytosis (1) Rpn11 none np   16336044
Combinatorial effect with methyl methanesulphonate (2) Rpn11 none sp   19543366
Mutant human huntingtin aggregation Rpn11 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Rpn11 Lethal np   20220848
Heat nociception (1) Rpn11 Developmentally lethal -0.77   21074052
Heat nociception (1) Rpn11 none -0.52   21074052
Regulated secretory pathway biogenesis (1) Rpn11 none -0.9   21149569
Heart development and function (1) Rpn11 none 0.69   20371351
Heart development and function (2) Rpn11 Decreased viability 3.08   20371351
Serratia marcescens infection (1) Rpn11 none 0.243589743589743   19520911
Notch pathway regulation (4) Rpn11 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) Rpn11 none 0   19363474
Hh pathway regulation Rpn11 Downregulation of Hh pathway -0.390454864256852   17903264
Hh pathway regulation Rpn11 Downregulation of Hh pathway -0.265773099597837   17903264
Adiposity regulation (1) Rpn11 none -0.395   20074523
Blood cell homeostasis regulation (1) Rpn11 none np   20540764
Blood cell homeostasis regulation (2) Rpn11 none np   20540764
S2 cell spreading Rpn11 none np   21041442
RTK-Ras-ERK pathway regulation (1) Rpn11 Decreased ERK phosphorylation after EGF stimulation -4.99 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Rpn11 Decreased ERK phosphorylation after EGF stimulation -3.42 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Rpn11 none -0.45 10 minutes sSpitz stimulation 22028469

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