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Gene : Prosalpha7 D. melanogaster

DB identifier  ? FBgn0023175 Secondary Identifier  ? CG1519
Name  ? Proteasome alpha7 subunit Source  FlyBase
  • synonyms:
  • CG1519,
  • 1519,
  • 20S proteasome subunit alpha-7,
  • PSA3_DROME,
  • alpha7_dm,
  • FBgn0023175,
  • PROSalpha7,
  • FBan0001519,
  • Proteasome subunit alpha type-3,
  • Alpha7,
  • 20S proteasome,
  • Alpha-7,
  • CPalpha7,
  • 20S proteasome subunit alpha 7,
  • alpha-subunit of 20S proteasome,
  • Proteasome alpha7 subunit

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6 Alleles

DB identifier Symbol Allele Class Organism
FBal0257101 Prosalpha7[HMS00068]   Drosophila melanogaster
FBal0286865 Prosalpha7[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286866 Prosalpha7[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0208128 Prosalpha7[GD3491]   Drosophila melanogaster
FBal0236181 Prosalpha7[KK109262]   Drosophila melanogaster
FBal0272129 Prosalpha7[NIG.1519R]   Drosophila melanogaster

97 Clones

Secondary Identifier DB identifier
UUGC0331 FBcl0000067
AT20314 FBcl0039599
AT05555 FBcl0039601
AT18347 FBcl0039603
AT20471 FBcl0039605
AT17601 FBcl0039609
AT25546 FBcl0039611
AT06112 FBcl0039615
AT31291 FBcl0039617
AT16929 FBcl0039619
EK110506 FBcl0130864
GH07345 FBcl0130881
GH01814 FBcl0130917
GH26573 FBcl0130919
GH27066 FBcl0130927
GH15443 FBcl0130935
GH16755 FBcl0130951
EK182311 FBcl0130980
EK067960 FBcl0130986
EK211611 FBcl0131014
EK248623 FBcl0131026
EK266739 FBcl0131038
GM14068 FBcl0147962
LD08854 FBcl0161046
LD02545 FBcl0161054
LD07707 FBcl0161056
LD08074 FBcl0161059
LD08154 FBcl0161066
LD07653 FBcl0161075
LD09744 FBcl0161078

3 Exons

DB identifier Symbol
FBgn0023175:3 Prosalpha7:3
FBgn0023175:2 Prosalpha7:2
FBgn0023175:1 Prosalpha7:1

1 Transcripts

DB identifier Gene
FBtr0089998 Prosalpha7

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0089998-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0089998-3-prime-utr Drosophila melanogaster

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74 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
36018 NCBI Entrez Gene identifiers FBgn0023175
61847 BioGRID FBgn0023175

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2747.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2959.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2161.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 3022.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2881.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2575.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2489.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2370.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1907.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3051.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2684.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2188.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2588.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2383.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 3244.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2870.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2091.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1997.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 3002.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2326.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2259.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2883.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1404.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1177.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1904.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6078.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 4758.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2522.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2010.0
FBgn0023175 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2517.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0023175:3_FBgn0023175:2 Drosophila melanogaster
intron_FBgn0023175:2_FBgn0023175:1 Drosophila melanogaster

32 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation Prosalpha7 none -2.4   19216764
Lipid storage Prosalpha7 none 1.26813336   19067489
Lipid storage Prosalpha7 none -0.166707492   19067489
ERK signaling Prosalpha7 ERK activation reduced weak   17086199
Drosophila C virus infection Prosalpha7 Drosophila C virus replication down np   17040126
Intracellular Listeria monocytogenes infection Prosalpha7 Decreased GFP protein expression moderate   16020693
Constitutive protein secretion and Golgi organization (1) Prosalpha7 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Prosalpha7 none sp   16496002
NFAT signaling Prosalpha7 Decreased NFAT translocation 3   16511445
Candida albicans phagocytosis (1) Prosalpha7 none np   16336044
Combinatorial effect with methyl methanesulphonate (2) Prosalpha7 Synthetic lethal with methyl methanesulphonate sp   19543366
Mutant human huntingtin aggregation Prosalpha7 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Prosalpha7 Lethal np   20220848
Muscle morphogenesis and function (1) Prosalpha7 Lethal np   20220848
Heat nociception (1) Prosalpha7 Developmentally lethal -1.17   21074052
Heat nociception (1) Prosalpha7 Developmentally lethal -1.17   21074052
Heart development and function (1) Prosalpha7 Pupal lethal 0.3   20371351
Heart development and function (2) Prosalpha7 Decreased viability 5.49   20371351
Serratia marcescens infection (1) Prosalpha7 none -0.123711340206185   19520911
Serratia marcescens infection (1) Prosalpha7 none 0.07   19520911
Notch pathway regulation (4) Prosalpha7 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Prosalpha7 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (1) Prosalpha7 Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) Prosalpha7 none np en-GAL4 20493818
Notch pathway regulation (3) Prosalpha7 Only lethal with Notch np   20493818
Adiposity regulation (1) Prosalpha7 none 0.151   20074523
RTK-Ras-ERK pathway regulation (1) Prosalpha7 Decreased ERK phosphorylation after EGF stimulation -1.59 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Prosalpha7 none -1.15 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Prosalpha7 none 1.4 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Prosalpha7 Increased ERK phosphorylation after sSpitz and EGF stimulation 2.36 10 minutes sSpitz stimulation 22028469

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