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Gene : ird5 D. melanogaster

DB identifier  ? FBgn0024222 Secondary Identifier  ? CG4201
Name  ? immune response deficient 5 Source  FlyBase
  • synonyms:
  • dIKK-beta,
  • LRK,
  • FBgn0024222,
  • mmune response deficient 5,
  • IKK-like protein,
  • LPS-responsive-kinase,
  • immune response-deficient 5,
  • ird5/DmIkk[beta],
  • Immune response deficient 5,
  • unnamed,
  • Lipopolysaccharide activated kinase,
  • CG4201,
  • dIKKbeta,
  • DmIKKBeta,
  • Lak,
  • IRD5,
  • FBgn0028726,
  • DLAK,
  • IK,
  • LPS-responsive kinase,
  • cactus kinase,
  • FBgn0029160,
  • FBgn0028725,
  • DIK,
  • IKK,
  • ird,
  • DmIKK,
  • IKKB,
  • dIKK,
  • IKK-beta,
  • anon-89Bd,
  • DmIKKb,
  • FBan0004201,
  • FBgn0029099,
  • IRD-5,
  • IKKbeta

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18 Alleles

DB identifier Symbol Allele Class Organism
FBal0243400 ird5[F22]   Drosophila melanogaster
FBal0159139 ird5[EY02434]   Drosophila melanogaster
FBal0147092 ird5[KG08072]   Drosophila melanogaster
FBal0121715 ird5[2] loss of function allele Drosophila melanogaster
FBal0155184 ird5[dsRNA.cPa]   Drosophila melanogaster
FBal0120474 ird5[K50A.MtnA]   Drosophila melanogaster
FBal0127960 ird5[unspecified]   Drosophila melanogaster
FBal0144230 ird5[dsRNA.cSb]   Drosophila melanogaster
FBal0086536 ird5[1] loss of function allele Drosophila melanogaster
FBal0120473 ird5[MtnA.PS]   Drosophila melanogaster
FBal0120472 ird5[dsRNA.cSa]   Drosophila melanogaster
FBal0262546 ird5[GL00058]   Drosophila melanogaster
FBal0104113 ird5[Act5C.T:Zzzz\His6]   Drosophila melanogaster
FBal0104112 ird5[K50A.Act5C.T:Zzzz\His6]   Drosophila melanogaster
FBal0104111 ird5[K50A.MtnA.T:Zzzz\His6]   Drosophila melanogaster
FBal0104110 ird5[MtnA.T:Zzzz\His6]   Drosophila melanogaster
FBal0121714 ird5[Scer\UAS.cLa]   Drosophila melanogaster
FBal0209741 ird5[GD11248]   Drosophila melanogaster

103 Clones

Secondary Identifier DB identifier
EK053505 FBcl0054516
EK183017 FBcl0054558
GM10440 FBcl0142551
LD09214 FBcl0160787
LD21354 FBcl0176028
LD44693 FBcl0176192
RE46673 FBcl0230154
RE29634 FBcl0230214
RE18595 FBcl0230226
SD09526 FBcl0287698
SD19220 FBcl0287701
EC054964 FBcl0299876
EC055437 FBcl0299877
EC055441 FBcl0299878
EC056345 FBcl0299879
EC056585 FBcl0299880
FGH107D04 FBcl0387101
RP003540033 FBcl0541772
RP003173420 FBcl0541766
RP003447397 FBcl0541768
RP003214675 FBcl0541769
RP003520524 FBcl0541770
RP003490914 FBcl0541771
RP003122649 FBcl0541773
RP003207318 FBcl0541775
RP003681645 FBcl0541777
RP003344021 FBcl0541778
RP003572647 FBcl0541780
RP003541846 FBcl0541781
RP003395610 FBcl0541782

5 Exons

DB identifier Symbol
FBgn0024222:5 ird5:5
FBgn0024222:4 ird5:4
FBgn0024222:3 ird5:3
FBgn0024222:2 ird5:2
FBgn0024222:1 ird5:1

1 Transcripts

DB identifier Gene
FBtr0304804 ird5

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0304804-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0304804-3-prime-utr Drosophila melanogaster

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Other

74 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
44432 NCBI Entrez Gene identifiers FBgn0024222
69058 BioGRID FBgn0024222

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 406.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 353.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 487.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 449.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 594.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 253.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 768.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 909.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 423.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1149.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 741.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 376.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1060.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 288.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 276.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 326.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 444.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 244.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 547.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 435.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 564.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 635.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 609.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1359.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 502.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1435.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 635.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 556.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 645.0
FBgn0024222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 535.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0024222:5_FBgn0024222:4 Drosophila melanogaster
intron_FBgn0024222:4_FBgn0024222:3 Drosophila melanogaster
intron_FBgn0024222:3_FBgn0024222:2 Drosophila melanogaster
intron_FBgn0024222:2_FBgn0024222:1 Drosophila melanogaster

23 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage ird5 none -0.07505239   19067489
Lipid storage ird5 none 3.760418376   19067489
Cell cycle regulation (1) ird5 none np   15616552
Cell cycle regulation (2) ird5 none np   15616552
Innate immunity ird5 Decreased IMD/Rel reporter activity -6.5   16170305
Cell size and cell-cycle regulation (1) ird5 none sp   16496002
Cell size and cell-cycle regulation (1) ird5 none sp   16496002
Muscle morphogenesis and function (1) ird5 none np   20220848
Heat nociception (1) ird5 none 0.12   21074052
Heart development and function (1) ird5 none 1   20371351
Serratia marcescens infection (1) ird5 none -0.683333333333333   19520911
Notch pathway regulation (4) ird5 none 0   19363474
PGN-induced dJNK phosphorylation ird5 Increased P-JNK protein expression with PGN 6.23 15 min PGN induction 19893628
PGN-induced dJNK phosphorylation ird5 Increased P-JNK protein expression with PGN 7.74 60 min PGN induction 19893628
Adiposity regulation (1) ird5 none 0.08   20074523
Actin organization and cell morphology (1) ird5 none np   19265526
Actin organization and cell morphology (2) ird5 none np   19265526
Actin organization and cell morphology (3) ird5 none np   19265526
Actin organization and cell morphology (4) ird5 Altered cell morphology np   19265526
Actin organization and cell morphology (5) ird5 none np   19265526
Actin organization and cell morphology (6) ird5 Altered cell morphology np   19265526
Vaccinia virus infection ird5 none sp   20585561
Hippo pathway regulation ird5 none 1.5   23263283

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