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Gene : PDZ-GEF D. melanogaster

DB identifier  ? FBgn0265778 Secondary Identifier  ? CG9491
Name  ? PDZ domain-containing guanine nucleotide exchange factor Source  FlyBase
  • synonyms:
  • l(2)k13720,
  • FBgn0265778,
  • D-PDZGEF,
  • GEF,
  • FBan0009491,
  • dPDZ-GEF,
  • FBgn0021873,
  • Dizzy,
  • FBgn0031798,
  • FBgn0069356,
  • Gef26,
  • CG9491,
  • DGEF,
  • FBgn0082671,
  • PDZ-GEF/Dizzy,
  • Dzy,
  • PDF-GEF Dizzy,
  • PDZ-GEF,
  • FBgn0265624

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24 Alleles

DB identifier Symbol Allele Class Organism
FBal0240268 PDZ-GEF[HM05139]   Drosophila melanogaster
FBal0216664 PDZ-GEF[6]   Drosophila melanogaster
FBal0216663 PDZ-GEF[5]   Drosophila melanogaster
FBal0193637 PDZ-GEF[P-RV4]   Drosophila melanogaster
FBal0245946 PDZ-GEF[JF01765]   Drosophila melanogaster
FBal0193638 PDZ-GEF[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0216661 PDZ-GEF[3]   Drosophila melanogaster
FBal0193631 PDZ-GEF[Delta5] amorphic allele - genetic evidence Drosophila melanogaster
FBal0216666 PDZ-GEF[+t11.6]   Drosophila melanogaster
FBal0193632 PDZ-GEF[Delta7] amorphic allele - genetic evidence Drosophila melanogaster
FBal0193635 PDZ-GEF[Delta10] amorphic allele - genetic evidence Drosophila melanogaster
FBal0193634 PDZ-GEF[Delta3] amorphic allele - genetic evidence Drosophila melanogaster
FBal0231892 PDZ-GEF[KK102612]   Drosophila melanogaster
FBal0197137 PDZ-GEF[rv-1]   Drosophila melanogaster
FBal0193630 PDZ-GEF[Delta1] amorphic allele - genetic evidence Drosophila melanogaster
FBal0193633 PDZ-GEF[Delta8] amorphic allele - genetic evidence Drosophila melanogaster
FBal0207104 PDZ-GEF[GD14231]   Drosophila melanogaster
FBal0193636 PDZ-GEF[Delta12] amorphic allele - genetic evidence Drosophila melanogaster
FBal0223149 PDZ-GEF[DG25507]   Drosophila melanogaster
FBal0064121 PDZ-GEF[k13720] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0193629 PDZ-GEF[EP388] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0216665 PDZ-GEF[unspecified]   Drosophila melanogaster
FBal0216662 PDZ-GEF[4]   Drosophila melanogaster
FBal0276433 PDZ-GEF[NIG.9491R]   Drosophila melanogaster

50 Clones

Secondary Identifier DB identifier
AT08279 FBcl0020871
EK219631 FBcl0047092
EK070744 FBcl0047170
EK158863 FBcl0049074
EK162156 FBcl0049356
EK047847 FBcl0049366
EK195852 FBcl0049376
EK292203 FBcl0049386
EK121927 FBcl0049398
EK067011 FBcl0049420
EK098939 FBcl0049438
EK302531 FBcl0049482
EK293825 FBcl0049498
EK142840 FBcl0049878
EK300618 FBcl0049962
EK119914 FBcl0049976
EK027416 FBcl0049988
EK183201 FBcl0050000
EK058720 FBcl0050016
EK271202 FBcl0050028
EK073546 FBcl0050038
EK073610 FBcl0050100
EK188027 FBcl0050178
EP08115 FBcl0080081
EP06815 FBcl0080089
EP03154 FBcl0080195
EP15643 FBcl0080197
EP15712 FBcl0080201
EP08329 FBcl0080207
RH14042 FBcl0246929

11 Exons

DB identifier Symbol
FBgn0021873:3 Gef26:3
FBgn0021873:2 Gef26:2
FBgn0021873:4 Gef26:4
FBgn0021873:5 Gef26:5
FBgn0021873:6 Gef26:6
FBgn0021873:8 Gef26:8
FBgn0021873:9 Gef26:9
FBgn0021873:10 Gef26:10
FBgn0021873:7 Gef26:7
FBgn0021873:1 Gef26:1
FBgn0021873:11 Gef26:11

4 Transcripts

DB identifier Gene
FBtr0300038 PDZ-GEF
FBtr0079249 PDZ-GEF
FBtr0333242 PDZ-GEF
FBtr0300039 PDZ-GEF

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0079249-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300038-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300039-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333242-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079249-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0300038-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0300039-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333242-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
33881 NCBI Entrez Gene identifiers FBgn0265778
60038 BioGRID FBgn0265778

9 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

12 Introns

DB identifier
Organism . Name
intron_FBgn0021873:2_FBgn0021873:3 Drosophila melanogaster
intron_FBgn0021873:3_FBgn0021873:4 Drosophila melanogaster
intron_FBgn0021873:4_FBgn0021873:5 Drosophila melanogaster
intron_FBgn0021873:5_FBgn0021873:6 Drosophila melanogaster
intron_FBgn0021873:6_FBgn0021873:7 Drosophila melanogaster
intron_FBgn0021873:7_FBgn0021873:9 Drosophila melanogaster
intron_FBgn0021873:9_FBgn0021873:10 Drosophila melanogaster
intron_FBgn0021873:6_FBgn0021873:8 Drosophila melanogaster
intron_FBgn0021873:8_FBgn0021873:9 Drosophila melanogaster
intron_FBgn0021873:1_FBgn0021873:3 Drosophila melanogaster
intron_FBgn0021873:9_FBgn0021873:11 Drosophila melanogaster
intron_FBgn0021873:6_FBgn0021873:9 Drosophila melanogaster

20 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage PDZ-GEF none -1.590294758   19067489
Lipid storage PDZ-GEF none 0.788167957   19067489
Cell size and cell-cycle regulation (1) PDZ-GEF none sp   16496002
Cell size and cell-cycle regulation (1) PDZ-GEF none sp   16496002
Muscle morphogenesis and function (1) PDZ-GEF none np   20220848
Muscle morphogenesis and function (1) PDZ-GEF none np   20220848
Heat nociception (1) PDZ-GEF none -1.17   21074052
Heat nociception (1) PDZ-GEF none -1.17   21074052
Heart development and function (1) PDZ-GEF none 1   20371351
Heart development and function (2) PDZ-GEF Decreased viability 5.43   20371351
Serratia marcescens infection (1) PDZ-GEF none -0.397727272727272   19520911
Notch pathway regulation (4) PDZ-GEF Bristle morphology defects, planar polarity defects sp   19363474
Notch pathway regulation (4) PDZ-GEF Bristle morphology defects 4   19363474
Adiposity regulation (1) PDZ-GEF none 0.014   20074523
RTK-Ras-ERK pathway regulation (1) PDZ-GEF Decreased ERK phosphorylation after EGF stimulation -1.77 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) PDZ-GEF none -0.47 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) PDZ-GEF none 1.11 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) PDZ-GEF none -0.89 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation PDZ-GEF none 0.45   23263283
Glycosylation regulation (1) PDZ-GEF none sp   21203496

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