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Gene : Prosbeta5 D. melanogaster

DB identifier  ? FBgn0029134 Secondary Identifier  ? CG12323
Name  ? Proteasome beta5 subunit Source  FlyBase
  • synonyms:
  • anon-WO0118547.116,
  • Prosbeta5,
  • PSMB5,
  • FBan0012323,
  • 20S proteasome,
  • beta5,
  • FBgn0033553,
  • FBgn0062234,
  • FBgn0029134,
  • dbeta5,
  • Beta-5,
  • LD08717,
  • Pros b5,
  • CG12323

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11 Alleles

DB identifier Symbol Allele Class Organism
FBal0286435 Prosbeta5[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286436 Prosbeta5[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0182144 Prosbeta5[f03598]   Drosophila melanogaster
FBal0156047 Prosbeta5[EP2619]   Drosophila melanogaster
FBal0134180 Prosbeta5[dsRNA.cWa]   Drosophila melanogaster
FBal0263124 Prosbeta5[HMS00119]   Drosophila melanogaster
FBal0208131 Prosbeta5[GD7568]   Drosophila melanogaster
FBal0221303 Prosbeta5[Delta1]   Drosophila melanogaster
FBal0221919 Prosbeta5[CB-0768-3]   Drosophila melanogaster
FBal0231247 Prosbeta5[KK101404]   Drosophila melanogaster
FBal0238829 Prosbeta5[DP00085]   Drosophila melanogaster

98 Clones

Secondary Identifier DB identifier
EC13760 FBcl0067729
EK148416 FBcl0096138
EK204949 FBcl0096172
EK154106 FBcl0096226
GH04561 FBcl0131473
GH03320 FBcl0131865
GH05416 FBcl0131897
GH07604 FBcl0132029
GM07976 FBcl0141733
GM30339 FBcl0146326
LD06379 FBcl0161289
LD08717 FBcl0161342
LD06910 FBcl0161375
LD28833 FBcl0176857
LP02869 FBcl0189853
LP08570 FBcl0189854
RE71166 FBcl0232302
RE66256 FBcl0232306
RE60552 FBcl0232310
RE59976 FBcl0232314
RE43786 FBcl0232418
RE64622 FBcl0232452
RE59776 FBcl0232480
RE62050 FBcl0232494
RE59480 FBcl0232505
RE10534 FBcl0232511
RE14474 FBcl0232519
RE52416 FBcl0232664
RE10969 FBcl0232688
RE39783 FBcl0232718

4 Exons

DB identifier Symbol
FBgn0029134:1 Prosbeta5:1
FBgn0029134:3 Prosbeta5:3
FBgn0029134:4 Prosbeta5:4
FBgn0029134:2 Prosbeta5:2

2 Transcripts

DB identifier Gene
FBtr0088224 Prosbeta5
FBtr0088225 Prosbeta5

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0088224-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088225-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088224-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088225-3-prime-utr Drosophila melanogaster

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74 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
45269 NCBI Entrez Gene identifiers FBgn0029134
69549 BioGRID FBgn0029134

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3228.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 4052.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2235.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 4007.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2624.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 3759.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2840.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2688.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 3400.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3419.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2933.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2610.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2555.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 3936.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 3480.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 3361.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2069.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2437.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 4266.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2870.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 3402.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 4048.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2691.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1869.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2031.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6017.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 5662.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2824.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1687.0
FBgn0029134 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2138.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0029134:1_FBgn0029134:3 Drosophila melanogaster
intron_FBgn0029134:3_FBgn0029134:4 Drosophila melanogaster
intron_FBgn0029134:2_FBgn0029134:4 Drosophila melanogaster

37 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Prosbeta5 none -0.45696987   19067489
Lipid storage Prosbeta5 none 0.548103043   19067489
ERK signaling Prosbeta5 ERK activation reduced weak   17086199
Intracellular Listeria monocytogenes infection Prosbeta5 Decreased GFP protein expression strong   16020693
Hedgehog signaling Prosbeta5 Decreased Hedgehog reporter activity -2.04   16311596
Constitutive protein secretion and Golgi organization (1) Prosbeta5 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Prosbeta5 Decreased viability sp   16496002
Cell size and cell-cycle regulation (2) Prosbeta5 none 1.204   16496002
Cell size and cell-cycle regulation (3) Prosbeta5 none 421   16496002
Candida albicans phagocytosis (1) Prosbeta5 none np   16336044
Combinatorial effect with methyl methanesulphonate (2) Prosbeta5 none sp   19543366
Mutant human huntingtin aggregation Prosbeta5 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Prosbeta5 Lethal np   20220848
Muscle morphogenesis and function (1) Prosbeta5 Lethal np   20220848
Heat nociception (1) Prosbeta5 none -1.17   21074052
Heart development and function (1) Prosbeta5 none 1   20371351
Heart development and function (2) Prosbeta5 Decreased viability 3.47   20371351
Serratia marcescens infection (1) Prosbeta5 Decreased viability after Serratia marcescens infection -2.05   19520911
Serratia marcescens infection (2) Prosbeta5 Decreased viability after Serratia marcescens infection sp   19520911
Serratia marcescens infection (3) Prosbeta5 Viable np   19520911
Serratia marcescens infection (4) Prosbeta5 Decreased viability after Serratia marcescens infection sp   19520911
Notch pathway regulation (4) Prosbeta5 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) Prosbeta5 Completely lethal (before pupal) sp   19363474
Hh pathway regulation Prosbeta5 none -0.219000510395462   17903264
Hh pathway regulation Prosbeta5 none -0.174464856980621   17903264
Self-renewal and differentiation in neural stem cells Prosbeta5 GFP aggregates number, GFP aggregates size, neuroblast more large cells, neuroblast cell shape, ganglion mother cell larger cell size, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast overproliferation, neuroblast underprolife sp   21549331
Adiposity regulation (1) Prosbeta5 Decreased triglyceride expression -0.274   20074523
Adiposity regulation (2) Prosbeta5 Lethal or developmental delay d/l   20074523
Adiposity regulation (3) Prosbeta5 none -0.06   20074523
Adiposity regulation (4) Prosbeta5 Lethal or developmental delay d/l   20074523

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