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Gene : Eip74EF D. melanogaster

DB identifier  ? FBgn0000567 Secondary Identifier  ? CG32180
Name  ? Ecdysone-induced protein 74EF Source  FlyBase
  • synonyms:
  • ecdysone induced protein 74EF,
  • E74B,
  • CG6273,
  • 3.3,
  • eip74ef,
  • E74-B,
  • FBan0032180,
  • Eip74 A,
  • E-74,
  • ECIP,
  • Ecdysone-induced-protein 74EF,
  • FBgn0026806,
  • Eip74E,
  • E74A/B,
  • FBgn0052180,
  • mE74,
  • E74,
  • FBgn0036739,
  • E74A,
  • CG32180,
  • ecdysone inducible protein,
  • CG6285,
  • Ecdysone-induced prot 74EF,
  • FBgn0000567,
  • l(3)neo24,
  • Eip74A,
  • l(3)24,
  • FBgn0011459

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49 Alleles

DB identifier Symbol Allele Class Organism
FBal0190012 Eip74EF[dsRNA.A.cKa]   Drosophila melanogaster
FBal0190464 Eip74EF[dsRNA.B.cKa]   Drosophila melanogaster
FBal0183707 Eip74EF[DG12412]   Drosophila melanogaster
FBal0183692 Eip74EF[d11079]   Drosophila melanogaster
FBal0264141 Eip74EF[MI04013]   Drosophila melanogaster
FBal0183695 Eip74EF[d07067]   Drosophila melanogaster
FBal0183700 Eip74EF[d03802]   Drosophila melanogaster
FBal0183687 Eip74EF[e04422]   Drosophila melanogaster
FBal0183688 Eip74EF[e04421]   Drosophila melanogaster
FBal0276903 Eip74EF[G15347]   Drosophila melanogaster
FBal0183691 Eip74EF[d11456]   Drosophila melanogaster
FBal0183693 Eip74EF[d08971]   Drosophila melanogaster
FBal0183694 Eip74EF[d08528]   Drosophila melanogaster
FBal0183697 Eip74EF[d07032]   Drosophila melanogaster
FBal0183696 Eip74EF[d07054]   Drosophila melanogaster
FBal0183698 Eip74EF[d06283]   Drosophila melanogaster
FBal0183699 Eip74EF[d04647]   Drosophila melanogaster
FBal0183701 Eip74EF[d02346]   Drosophila melanogaster
FBal0183702 Eip74EF[d00990]   Drosophila melanogaster
FBal0183703 Eip74EF[d00907]   Drosophila melanogaster
FBal0183704 Eip74EF[d00633]   Drosophila melanogaster
FBal0183705 Eip74EF[d00570]   Drosophila melanogaster
FBal0183684 Eip74EF[f06965]   Drosophila melanogaster
FBal0183685 Eip74EF[f06771]   Drosophila melanogaster
FBal0183686 Eip74EF[f02844]   Drosophila melanogaster
FBal0183689 Eip74EF[e02347]   Drosophila melanogaster
FBal0183690 Eip74EF[e01002]   Drosophila melanogaster
FBal0183706 Eip74EF[c01811]   Drosophila melanogaster
FBal0011039 Eip74EF[neo24] amorphic allele - genetic evidence, loss of function allele Drosophila melanogaster
FBal0156470 Eip74EF[BG01805]   Drosophila melanogaster

51 Clones

Secondary Identifier DB identifier
AT19301 FBcl0006345
EP11724 FBcl0075921
EK160523 FBcl0078344
EK025935 FBcl0078364
EK270211 FBcl0101916
EK185062 FBcl0101924
EK155336 FBcl0101932
EK200462 FBcl0101938
EK139451 FBcl0101942
EK186726 FBcl0101946
EK130632 FBcl0101960
EK234218 FBcl0101990
EK061039 FBcl0101994
LP02487 FBcl0179665
LP01487 FBcl0179726
LP01488 FBcl0179728
LP06015 FBcl0179731
RE66025 FBcl0194057
RH46031 FBcl0241491
RH17937 FBcl0241698
SD03570 FBcl0277592
SD07932 FBcl0277603
SD05729 FBcl0277607
EC068154 FBcl0303334
IP15828 FBcl0304182
FI19001 FBcl0742881
EK140139 FBcl0358454
EK295313 FBcl0358455
IP15728 FBcl0358456
IP15628 FBcl0358457

11 Exons

DB identifier Symbol
FBgn0000567:11 Eip74EF:11
FBgn0000567:10 Eip74EF:10
FBgn0000567:9 Eip74EF:9
FBgn0000567:8 Eip74EF:8
FBgn0000567:7 Eip74EF:7
FBgn0000567:4 Eip74EF:4
FBgn0000567:3 Eip74EF:3
FBgn0000567:2 Eip74EF:2
FBgn0000567:6 Eip74EF:6
FBgn0000567:5 Eip74EF:5
FBgn0000567:1 Eip74EF:1

5 Transcripts

DB identifier Gene
FBtr0075204 Eip74EF
FBtr0075203 Eip74EF
FBtr0305796 Eip74EF
FBtr0075202 Eip74EF
FBtr0100411 Eip74EF

10 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075202-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075203-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075204-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0100411-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0305796-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075202-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075203-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075204-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0100411-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0305796-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
39962 NCBI Entrez Gene identifiers FBgn0000567

9 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 820.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 902.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 737.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 711.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 879.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 326.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 730.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 379.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 575.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 382.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 752.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 611.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 865.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 886.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1335.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 385.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1763.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 736.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 403.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1133.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1201.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 957.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 693.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 452.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 989.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 418.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 360.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 295.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 326.0
FBgn0000567 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 356.0

10 Introns

DB identifier
Organism . Name
intron_FBgn0000567:6_FBgn0000567:4 Drosophila melanogaster
intron_FBgn0000567:4_FBgn0000567:3 Drosophila melanogaster
intron_FBgn0000567:3_FBgn0000567:2 Drosophila melanogaster
intron_FBgn0000567:11_FBgn0000567:10 Drosophila melanogaster
intron_FBgn0000567:10_FBgn0000567:9 Drosophila melanogaster
intron_FBgn0000567:9_FBgn0000567:8 Drosophila melanogaster
intron_FBgn0000567:8_FBgn0000567:7 Drosophila melanogaster
intron_FBgn0000567:7_FBgn0000567:4 Drosophila melanogaster
intron_FBgn0000567:5_FBgn0000567:4 Drosophila melanogaster
intron_FBgn0000567:3_FBgn0000567:1 Drosophila melanogaster

28 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Eip74EF Decreased lipid droplet area -3.592741302   19067489
Lipid storage Eip74EF Decreased lipid droplet area -1.095105007   19067489
Lipid storage Eip74EF Decreased lipid droplet area -2.446669783   19067489
Lipid storage Eip74EF none 3.41036255   19067489
Lipid storage Eip74EF none 0.730263956   19067489
Wnt signaling Eip74EF Increased Wnt reporter activity 7.5   15817814
Constitutive protein secretion and Golgi organization (1) Eip74EF Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Eip74EF none sp   16496002
Cell size and cell-cycle regulation (1) Eip74EF none sp   16496002
Cell size and cell-cycle regulation (1) Eip74EF none sp   16496002
Dendrite pattern formation Eip74EF none np   16547170
Dendrite pattern formation Eip74EF none np   16547170
Brucella melitensis infection Eip74EF none 133.88   18654626
Mutant human huntingtin aggregation Eip74EF Decreased mutant human huntingtin aggregation <= -2   19789644
PGN-induced dJNK phosphorylation Eip74EF Increased P-JNK protein expression with PGN 3.42 15 min PGN induction 19893628
PGN-induced dJNK phosphorylation Eip74EF Increased P-JNK protein expression with PGN 2.51 60 min PGN induction 19893628
Toll-dependent innate immune pathway regulation Eip74EF Downregulation of Toll pathway after hEGF stimulation -3.56   20375635
Blood cell homeostasis regulation (1) Eip74EF none np   20540764
Blood cell homeostasis regulation (1) Eip74EF none np   20540764
Blood cell homeostasis regulation (2) Eip74EF none np   20540764
Blood cell homeostasis regulation (2) Eip74EF none np   20540764
RTK-Ras-ERK pathway regulation (1) Eip74EF none -1.07 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Eip74EF Increased ERK phosphorylation after EGF stimulation 1.9 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Eip74EF none 1.38 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Eip74EF Increased ERK phosphorylation after sSpitz and EGF stimulation 1.61 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Eip74EF none 0.66   23263283
Glycosylation regulation (1) Eip74EF none sp   21203496
Glycosylation regulation (1) Eip74EF none sp   21203496

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