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Gene : Tor D. melanogaster

DB identifier  ? FBgn0021796 Secondary Identifier  ? CG5092
Name  ? Target of rapamycin Source  FlyBase
  • synonyms:
  • FBgn0021796,
  • l(2)k17004,
  • FRAP/TOR,
  • target of rapamycin kinase,
  • Target-of-rapamycin,
  • Tor|TOR,
  • unnamed,
  • dTOR,
  • mTOR,
  • 5092,
  • DmTOR,
  • TOR,
  • CT24817,
  • FBan0005092,
  • CG5092,
  • CT16317,
  • CT24745,
  • FBgn0032466,
  • Target Of Rapamycin

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40 Alleles

DB identifier Symbol Allele Class Organism
FBal0270250 Tor[Scer\UAS.cWa]   Drosophila melanogaster
FBal0270251 Tor[Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0279827 Tor[LL04239]   Drosophila melanogaster
FBal0120582 Tor[EP2353]   Drosophila melanogaster
FBal0181189 Tor[f00799]   Drosophila melanogaster
FBal0257579 Tor[HMS00904]   Drosophila melanogaster
FBal0064028 Tor[k17004]   Drosophila melanogaster
FBal0257777 Tor[HMS01114]   Drosophila melanogaster
FBal0246846 Tor[2L7]   Drosophila melanogaster
FBal0246847 Tor[2L15]   Drosophila melanogaster
FBal0244084 Tor[15]   Drosophila melanogaster
FBal0267730 Tor[Delta6B]   Drosophila melanogaster
FBal0217719 Tor[MB07988]   Drosophila melanogaster
FBal0120585 Tor[+t9.4]   Drosophila melanogaster
FBal0120586 Tor[DeltaP]   Drosophila melanogaster
FBal0189881 Tor[E161K] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0120583 Tor[2L1] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0120584 Tor[2L19]   Drosophila melanogaster
FBal0120579 Tor[unspecified]   Drosophila melanogaster
FBal0120581 Tor[RR]   Drosophila melanogaster
FBal0190376 Tor[Q528stop] loss of function allele Drosophila melanogaster
FBal0190478 Tor[R248stop] loss of function allele Drosophila melanogaster
FBal0120580 Tor[RRKD]   Drosophila melanogaster
FBal0175777 Tor[dsRNA.cSa]   Drosophila melanogaster
FBal0150581 Tor[dsRNA.cGa]   Drosophila melanogaster
FBal0191560 Tor[R97C] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0191669 Tor[A948V] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0262633 Tor[GL00156]   Drosophila melanogaster
FBal0141343 Tor[FRB.Scer\UAS]   Drosophila melanogaster
FBal0190625 Tor[T:Ivir\HA1]   Drosophila melanogaster

17 Clones

Secondary Identifier DB identifier
EK093807 FBcl0083664
EK016839 FBcl0083668
EK294320 FBcl0083674
EP17351 FBcl0088311
GH22586 FBcl0111757
GM10438 FBcl0143359
RE25959 FBcl0204846
SD02269 FBcl0290888
EC051706 FBcl0301215
EC051710 FBcl0301216
EC054209 FBcl0301217
EC056021 FBcl0301218
CK01.99A.C5 FBcl0405349
CK01.17B.B6 FBcl0405352
214381.3 FBcl0405316
193549 FBcl0405344
191787 FBcl0405364

8 Exons

DB identifier Symbol
FBgn0021796:1 Tor:1
FBgn0021796:2 Tor:2
FBgn0021796:3 Tor:3
FBgn0021796:5 Tor:5
FBgn0021796:6 Tor:6
FBgn0021796:7 Tor:7
FBgn0021796:8 Tor:8
FBgn0021796:4 Tor:4

2 Transcripts

DB identifier Gene
FBtr0080422 Tor
FBtr0336615 Tor

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0080422-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0336615-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080422-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0336615-3-prime-utr Drosophila melanogaster

Interactions

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Other

55 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
47396 NCBI Entrez Gene identifiers FBgn0021796
70789 BioGRID FBgn0021796

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 599.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 501.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 591.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 566.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 606.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 425.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 414.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 601.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 317.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 997.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 974.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 570.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 443.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 701.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 812.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 436.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 760.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 596.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 801.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 524.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 655.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 516.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 654.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 494.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 795.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1278.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 436.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 771.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 539.0
FBgn0021796 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 444.0

8 Introns

DB identifier
Organism . Name
intron_FBgn0021796:1_FBgn0021796:2 Drosophila melanogaster
intron_FBgn0021796:2_FBgn0021796:3 Drosophila melanogaster
intron_FBgn0021796:3_FBgn0021796:4 Drosophila melanogaster
intron_FBgn0021796:4_FBgn0021796:6 Drosophila melanogaster
intron_FBgn0021796:6_FBgn0021796:7 Drosophila melanogaster
intron_FBgn0021796:7_FBgn0021796:8 Drosophila melanogaster
intron_FBgn0021796:3_FBgn0021796:5 Drosophila melanogaster
intron_FBgn0021796:5_FBgn0021796:6 Drosophila melanogaster

36 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation Tor none -1.6   19216764
Lipid storage Tor none -0.518791313   19067489
Lipid storage Tor none -0.933342584   19067489
Chlamydia caviae infection Tor Decreased Chlamydia caviae infection np   17967059
ERK signaling Tor ERK activation increased strong   17086199
Cell cycle regulation (1) Tor Increased G1 DNA content, decreased cell size, decreased cytokinetic index sp   15616552
Cell cycle regulation (2) Tor none np   15616552
Intracellular Listeria monocytogenes infection Tor Decreased GFP protein expression moderate   16020693
Cell size and cell-cycle regulation (1) Tor Increased G1 DNA content sp   16496002
Cell size and cell-cycle regulation (1) Tor none sp   16496002
Cell size and cell-cycle regulation (1) Tor none sp   16496002
Cell size and cell-cycle regulation (1) Tor none sp   16496002
Cell size and cell-cycle regulation (1) Tor none sp   16496002
Cell size and cell-cycle regulation (2) Tor none 1.375   16496002
Cell size and cell-cycle regulation (3) Tor none 473   16496002
DFoxO signaling Tor Decreased dFoxO reporter activity 0.08   18815370
Combinatorial effect with methyl methanesulphonate (2) Tor Synthetic lethal with methyl methanesulphonate sp   19543366
Akt-TOR pathway negative feedback regulation Tor Decreased dAkt phosphorylation after insulin stimulation -2.6 10 min insulin stimulation 20585550
Notch pathway regulation (1) Tor Upregulation of Notch pathway np   20493818
Blood cell homeostasis regulation (1) Tor none np   20540764
Blood cell homeostasis regulation (2) Tor none np   20540764
Actin organization and cell morphology (1) Tor none np   19265526
Actin organization and cell morphology (2) Tor none np   19265526
Actin organization and cell morphology (3) Tor none np   19265526
Actin organization and cell morphology (4) Tor none np   19265526
Actin organization and cell morphology (5) Tor none np   19265526
Actin organization and cell morphology (6) Tor none np   19265526
Vaccinia virus infection Tor none sp   20585561
RTK-Ras-ERK pathway regulation (1) Tor none 0.01 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Tor none 0.3 10 minutes EGF stimulation 22028469

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