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Gene : Uba2 D. melanogaster

DB identifier  ? FBgn0029113 Secondary Identifier  ? CG7528
Name  ? Smt3 activating enzyme 2 Source  FlyBase
  • synonyms:
  • FBan0007528,
  • FBgn0024190,
  • DmUba2,
  • ubiquitin-activating enzyme (E1),
  • SAE2,
  • dUba2,
  • sip2,
  • FBgn0040287,
  • UBA2,
  • L36,
  • Ubc2,
  • FBgn0029113,
  • DmSAE2,
  • CG7528,
  • FBgn0035840,
  • Smt3-activating enzyme 2

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15 Alleles

DB identifier Symbol Allele Class Organism
FBal0276845 Uba2[N2] amorphic allele - molecular evidence Drosophila melanogaster
FBal0276846 Uba2[C3] amorphic allele - molecular evidence Drosophila melanogaster
FBal0276847 Uba2[+t4.4]   Drosophila melanogaster
FBal0276848 Uba2[Scer\UAS.cKa]   Drosophila melanogaster
FBal0276896 Uba2[G4384]   Drosophila melanogaster
FBal0276897 Uba2[G6571]   Drosophila melanogaster
FBal0276898 Uba2[G8583]   Drosophila melanogaster
FBal0259132 Uba2[KK102220]   Drosophila melanogaster
FBal0262918 Uba2[GL00452]   Drosophila melanogaster
FBal0103991 Uba2[Act5C.T:Ivir\HA1]   Drosophila melanogaster
FBal0121879 Uba2[C175S.Scer\UAS]   Drosophila melanogaster
FBal0121878 Uba2[Scer\UAS.cLa]   Drosophila melanogaster
FBal0239387 Uba2[HM05055]   Drosophila melanogaster
FBal0214845 Uba2[GD12265]   Drosophila melanogaster
FBal0275604 Uba2[NIG.7528R]   Drosophila melanogaster

158 Clones

Secondary Identifier DB identifier
AT09569 FBcl0031427
EP03302 FBcl0085217
EK134204 FBcl0104988
EK029406 FBcl0105026
EK122133 FBcl0105030
EK105349 FBcl0105032
EK292916 FBcl0105034
EK262329 FBcl0105038
EK167801 FBcl0105040
EK226055 FBcl0105042
EK109622 FBcl0105044
GM03210 FBcl0142476
GM10118 FBcl0142480
GM29953 FBcl0147140
GM20503 FBcl0147142
GM29927 FBcl0147144
GM25621 FBcl0147145
LD12741 FBcl0153467
LD07585 FBcl0153469
LD15109 FBcl0153470
LD03281 FBcl0153471
LD09943 FBcl0153472
LD11358 FBcl0153473
LD20144 FBcl0153474
LD12918 FBcl0153475
LD20715 FBcl0153476
LD01184 FBcl0153477
LD07232 FBcl0153478
LD14253 FBcl0153479
LD05280 FBcl0153480

4 Exons

DB identifier Symbol
FBgn0029113:4 Uba2:4
FBgn0029113:3 Uba2:3
FBgn0029113:2 Uba2:2
FBgn0029113:1 Uba2:1

1 Transcripts

DB identifier Gene
FBtr0076734 Uba2

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0076734-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0076734-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
44496 NCBI Entrez Gene identifiers FBgn0029113
69084 BioGRID FBgn0029113

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1780.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2443.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1089.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1541.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1889.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 884.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 707.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1181.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1182.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1195.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1178.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 972.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 894.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1293.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1554.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 988.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1290.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1121.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1407.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1321.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1645.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2485.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1129.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 905.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1256.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2739.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2133.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1654.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1158.0
FBgn0029113 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1036.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0029113:4_FBgn0029113:3 Drosophila melanogaster
intron_FBgn0029113:3_FBgn0029113:2 Drosophila melanogaster
intron_FBgn0029113:2_FBgn0029113:1 Drosophila melanogaster

9 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Uba2 none 0.620338287   19067489
Lipid storage Uba2 none 1.10096391   19067489
Wnt signaling Uba2 Increased Wnt reporter activity 3.2   15817814
Cell size and cell-cycle regulation (1) Uba2 none sp   16496002
Combinatorial effect with methyl methanesulphonate (1) Uba2 Synthetic lethal with methyl methanesulphonate sp   19543366
Combinatorial effect with methyl methanesulphonate (2) Uba2 Synthetic lethal with methyl methanesulphonate sp   19543366
Hippo pathway regulation Uba2 none -0.04   23263283
Glycosylation regulation (1) Uba2 none sp   21203496
Huntingtin (Htt) aggregates formation Uba2 Decreased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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