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Gene : numb D. melanogaster

DB identifier  ? FBgn0002973 Secondary Identifier  ? CG3779
Name  ? numb Source  FlyBase
  • synonyms:
  • l(2)s2201,
  • FBgn0010532,
  • dNumb,
  • l(2)3235,
  • Nb,
  • CG3779,
  • l(2)03235,
  • FBgn0002973,
  • FBgn0010684,
  • Numb,
  • FBan0003779,
  • d-Numb,
  • numbs,
  • N7-1

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105 Alleles

DB identifier Symbol Allele Class Organism
FBal0282742 numb[Scer\UAS.T:Hsap\MYC.cBa]   Drosophila melanogaster
FBal0282743 numb[G2A.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0270134 numb[Scer\UAS.T:Avic\GFP]   Drosophila melanogaster
FBal0270135 numb[DeltaCT.Scer\UAS.T:Avic\GFP]   Drosophila melanogaster
FBal0178613 numb[EY16020]   Drosophila melanogaster
FBal0264150 numb[+t19.5]   Drosophila melanogaster
FBal0264151 numb[2del]   Drosophila melanogaster
FBal0178607 numb[f03898]   Drosophila melanogaster
FBal0178609 numb[e00763]   Drosophila melanogaster
FBal0178610 numb[c05511]   Drosophila melanogaster
FBal0178611 numb[c05449]   Drosophila melanogaster
FBal0245897 numb[JF01695]   Drosophila melanogaster
FBal0260478 numb[MI02935]   Drosophila melanogaster
FBal0276713 numb[DeltaPTB.Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0276712 numb[DeltaAB.Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0276714 numb[DeltaC.Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0276715 numb[Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0276716 numb[S2A.Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0276717 numb[S2D.Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0178606 numb[f05590]   Drosophila melanogaster
FBal0013186 numb[1] amorphic allele - genetic evidence, loss of function allele, hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0178608 numb[e03773]   Drosophila melanogaster
FBal0158873 numb[EY03840]   Drosophila melanogaster
FBal0158872 numb[EY03852]   Drosophila melanogaster
FBal0158874 numb[EP2505]   Drosophila melanogaster
FBal0119167 numb[EP2542]   Drosophila melanogaster
FBal0008018 numb[03235]   Drosophila melanogaster
FBal0009306 numb[s2201]   Drosophila melanogaster
FBal0129178 numb[J21]   Drosophila melanogaster
FBal0135657 numb[nuts]   Drosophila melanogaster

101 Clones

Secondary Identifier DB identifier
Dmel_neb_011270_0944_1111 FBcl0373437
DPiM_LD25907 FBcl0741764
164514 FBcl0397495
EK237359 FBcl0036422
EK097951 FBcl0036442
EK131519 FBcl0036462
EK161558 FBcl0036482
EK277603 FBcl0036502
EK091306 FBcl0036520
EK196837 FBcl0036536
EK150544 FBcl0036558
EK120141 FBcl0036574
AT22558 FBcl0022869
EK154753 FBcl0034676
EK196945 FBcl0036608
EK146149 FBcl0036622
EK156043 FBcl0034698
EK269936 FBcl0034718
EK104433 FBcl0036642
EK304529 FBcl0036660
EK304460 FBcl0036676
EK045118 FBcl0036720
EK065403 FBcl0034978
EK242217 FBcl0034998
EK229655 FBcl0035018
EK101922 FBcl0036816
EK122345 FBcl0036838
EK147354 FBcl0035166
EK180416 FBcl0036856
EK269011 FBcl0036876

8 Exons

DB identifier Symbol
FBgn0002973:3 numb:3
FBgn0002973:5 numb:5
FBgn0002973:6 numb:6
FBgn0002973:7 numb:7
FBgn0002973:1 numb:1
FBgn0002973:2 numb:2
FBgn0002973:4 numb:4
FBgn0002973:8 numb:8

3 Transcripts

DB identifier Gene
FBtr0079822 numb
FBtr0079821 numb
FBtr0339526 numb

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0079822-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0079821-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339526-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079822-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079821-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339526-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34263 NCBI Entrez Gene identifiers FBgn0002973
60366 BioGRID FBgn0002973

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 323.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 342.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 300.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 238.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 232.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 14.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 204.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 263.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 255.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 307.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 230.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 417.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 437.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 788.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1079.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 138.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 632.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 562.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 846.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 731.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 571.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 548.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 249.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 143.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 235.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1823.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1639.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1808.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2104.0
FBgn0002973 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1888.0

8 Introns

DB identifier
Organism . Name
intron_FBgn0002973:3_FBgn0002973:5 Drosophila melanogaster
intron_FBgn0002973:5_FBgn0002973:6 Drosophila melanogaster
intron_FBgn0002973:6_FBgn0002973:7 Drosophila melanogaster
intron_FBgn0002973:1_FBgn0002973:2 Drosophila melanogaster
intron_FBgn0002973:2_FBgn0002973:6 Drosophila melanogaster
intron_FBgn0002973:3_FBgn0002973:4 Drosophila melanogaster
intron_FBgn0002973:4_FBgn0002973:5 Drosophila melanogaster
intron_FBgn0002973:6_FBgn0002973:8 Drosophila melanogaster

18 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage numb none -1.088891322   19067489
Lipid storage numb none -1.501057763   19067489
Cell size and cell-cycle regulation (1) numb none sp   16496002
CD4 regulation by human immunodeficiency virus Type 1 Nef (HIV-1 Nef) numb none 3.19   17267500
Combinatorial effect with methyl methanesulphonate (1) numb none sp   19543366
Notch pathway regulation (1) numb Rare empty or multiple sockets rare, weak temperature: 18 19363474
Notch pathway regulation (1) numb Empty or multiple sockets, M only, head and notum rare, weak temperature: 25 19363474
Notch pathway regulation (1) numb Empty or multiple sockets medium to strong temperature: 29 19363474
Notch pathway regulation (2) numb Empty or multiple s ockets, M only, head and notum rare, weak temperature: 25 19363474
Notch pathway regulation (2) numb Empty or multiple sockets medium to strong temperature: 29 19363474
Notch pathway regulation (2) numb Empty or multiple sockets, mostly M, some m affected rare, weak temperature: 18 19363474
Notch pathway regulation (3) numb Strong empty or multiple sockets medium to strong temperature: 18 19363474
Notch pathway regulation (3) numb Strong empty or multiple sockets medium to strong temperature: 25 19363474
Notch pathway regulation (3) numb Strong empty or multiple sockets medium to strong temperature: 29 19363474
Notch pathway regulation (4) numb Empty or multiple sockets 9   19363474
Self-renewal and differentiation in neural stem cells numb Neuroblast more large cells, neuroblast overproliferation, lethal sp   21549331
Hippo pathway regulation numb none 0.67   23263283
Glycosylation regulation (1) numb none sp   21203496

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