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Gene : Pi3K92E D. melanogaster

DB identifier  ? FBgn0015279 Secondary Identifier  ? CG4141
Name  ? Pi3K92E Source  FlyBase
  • synonyms:
  • PI3K-92D,
  • PI3 kinase,
  • Phosphatidylinositol-3-kinase,
  • Dp110/PI3K,
  • FBgn0014938,
  • FBan0004141,
  • Dmp110,
  • p110 PI3 kinase,
  • dPI3K,
  • PI3K-92E/Dp110,
  • PI 3-kinase,
  • PiK92E,
  • phosphatidylinositol 3-kinase,
  • p120,
  • Pi3Kp110,
  • PI[[3]]K,
  • PI3-kinase,
  • PI-3-K,
  • FBgn0015279,
  • phosphoinositide 3-kinase,
  • class I PI(3)K,
  • CG4141,
  • Phosphoinositide-3 Kinase,
  • rea,
  • Phosphotidylinositol 3 kinase,
  • PI3Kinase92E,
  • phospho-inositol-3 kinase at 92E,
  • Pi3K92D,
  • PI3K92E,
  • Dp110,
  • phosphoinositide 3 kinase Dp110,
  • PI-3 kinase,
  • PI3K,
  • insulin-regulated PI3 kinase,
  • dPI 3-kinase,
  • anon-92Ed,
  • PI(3)K,
  • Pi3K92E|p110,
  • type-1 PI3K,
  • p110,
  • PI3K-Dp110,
  • PI3'K

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33 Alleles

DB identifier Symbol Allele Class Organism
FBal0218868 Pi3K92E[T:Hsap\MYC]   Drosophila melanogaster
FBal0182269 Pi3K92E[e03435]   Drosophila melanogaster
FBal0248868 Pi3K92E[dsRNA.cUa]   Drosophila melanogaster
FBal0100418 Pi3K92E[+t14.7]   Drosophila melanogaster
FBal0122035 Pi3K92E[wt.GMR]   Drosophila melanogaster
FBal0122036 Pi3K92E[DN.GMR]   Drosophila melanogaster
FBal0122037 Pi3K92E[ACT.GMR]   Drosophila melanogaster
FBal0156076 Pi3K92E[GMR.Exel]   Drosophila melanogaster
FBal0156078 Pi3K92E[CAAX.GMR] gain of function allele Drosophila melanogaster
FBal0156080 Pi3K92E[A2860C.GMR] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0098330 Pi3K92E[unspecified]   Drosophila melanogaster
FBal0100417 Pi3K92E[A]   Drosophila melanogaster
FBal0152313 Pi3K92E[5W3]   Drosophila melanogaster
FBal0123129 Pi3K92E[2H1]   Drosophila melanogaster
FBal0262779 Pi3K92E[GL00311]   Drosophila melanogaster
FBal0156079 Pi3K92E[A2860C.Scer\UAS] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0156077 Pi3K92E[CAAX.Scer\UAS] gain of function allele Drosophila melanogaster
FBal0058398 Pi3K92E[D954A.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0156075 Pi3K92E[Scer\UAS.Exel]   Drosophila melanogaster
FBal0058397 Pi3K92E[Scer\UAS.T:Hsap\MYC,T:Hsap\CAAX]   Drosophila melanogaster
FBal0058396 Pi3K92E[Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0217850 Pi3K92E[MB06212]   Drosophila melanogaster
FBal0240563 Pi3K92E[B]   Drosophila melanogaster
FBal0240564 Pi3K92E[Scer\UAS.cWa]   Drosophila melanogaster
FBal0287499 Pi3K92E[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0208070 Pi3K92E[GD11228]   Drosophila melanogaster
FBal0218869 Pi3K92E[t.RBD.T:Hsap\MYC]   Drosophila melanogaster
FBal0218870 Pi3K92E[6M5] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0218871 Pi3K92E[6V2] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0242352 Pi3K92E[JF02770]   Drosophila melanogaster

114 Clones

Secondary Identifier DB identifier
EK088409 FBcl0070596
EK087440 FBcl0073530
EK178364 FBcl0074026
EK217904 FBcl0074084
EK166219 FBcl0074208
EK242962 FBcl0074290
EK208905 FBcl0074344
EK075438 FBcl0074382
EK208663 FBcl0074404
EK049048 FBcl0074442
EK277605 FBcl0074448
EN17409 FBcl0097119
EN17139 FBcl0101979
GM19579 FBcl0146528
LD05455 FBcl0155546
LD11980 FBcl0155681
LD44429 FBcl0169061
RE68170 FBcl0210025
RE35886 FBcl0210026
RE71354 FBcl0210059
RE52001 FBcl0210449
RE64438 FBcl0210455
RE70445 FBcl0210459
RH35425 FBcl0253349
SD21952 FBcl0285565
SD26041 FBcl0285566
SD05105 FBcl0285567
SD11778 FBcl0285570
EC056638 FBcl0300073
EC054613 FBcl0300074

10 Exons

DB identifier Symbol
FBgn0015279:9 Pi3K92E:9
FBgn0015279:7 Pi3K92E:7
FBgn0015279:6 Pi3K92E:6
FBgn0015279:5 Pi3K92E:5
FBgn0015279:4 Pi3K92E:4
FBgn0015279:3 Pi3K92E:3
FBgn0015279:2 Pi3K92E:2
FBgn0015279:1 Pi3K92E:1
FBgn0015279:10 Pi3K92E:10
FBgn0015279:8 Pi3K92E:8

3 Transcripts

DB identifier Gene
FBtr0083940 Pi3K92E
FBtr0083941 Pi3K92E
FBtr0334643 Pi3K92E

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0083940-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0083941-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334643-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083940-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083941-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334643-3-prime-utr Drosophila melanogaster

Interactions

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Other

52 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42446 NCBI Entrez Gene identifiers FBgn0015279
67422 BioGRID FBgn0015279

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 487.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 441.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 509.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 510.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 493.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 555.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1611.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 798.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 564.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1039.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1268.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 355.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 972.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 548.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 593.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 543.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1288.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 509.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 523.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 486.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 498.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 599.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 727.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1414.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 594.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1291.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 621.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 948.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 718.0
FBgn0015279 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 536.0

9 Introns

DB identifier
Organism . Name
intron_FBgn0015279:8_FBgn0015279:7 Drosophila melanogaster
intron_FBgn0015279:7_FBgn0015279:6 Drosophila melanogaster
intron_FBgn0015279:6_FBgn0015279:5 Drosophila melanogaster
intron_FBgn0015279:5_FBgn0015279:4 Drosophila melanogaster
intron_FBgn0015279:4_FBgn0015279:3 Drosophila melanogaster
intron_FBgn0015279:3_FBgn0015279:2 Drosophila melanogaster
intron_FBgn0015279:2_FBgn0015279:1 Drosophila melanogaster
intron_FBgn0015279:9_FBgn0015279:7 Drosophila melanogaster
intron_FBgn0015279:10_FBgn0015279:7 Drosophila melanogaster

25 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation Pi3K92E none -1.11   19216764
Lipid storage Pi3K92E none -0.363854825   19067489
Lipid storage Pi3K92E none 0.381152094   19067489
Multipolar division Pi3K92E Centrosome clustering defects medium   18662975
Cell size and cell-cycle regulation (1) Pi3K92E none sp   16496002
Cell size and cell-cycle regulation (1) Pi3K92E none sp   16496002
Brucella melitensis infection Pi3K92E Decreased Brucella melitensis infection 57.68   18654626
P. aeruginosa infection Pi3K92E P. aeruginosa invasion decreased np   18369477
Combinatorial effect with methyl methanesulphonate (2) Pi3K92E none sp   19543366
Muscle morphogenesis and function (1) Pi3K92E Locomotion defect np   20220848
Heat nociception (1) Pi3K92E none -1.17   21074052
Heart development and function (1) Pi3K92E none 1   20371351
Serratia marcescens infection (1) Pi3K92E none -1.28571428571428   19520911
Serratia marcescens infection (1) Pi3K92E none 0.581196581196581   19520911
Notch pathway regulation (4) Pi3K92E Notum malformation death 5   19363474
Notch pathway regulation (4) Pi3K92E Notum malformation death 4   19363474
Actin organization and cell morphology (1) Pi3K92E none np   19265526
Actin organization and cell morphology (2) Pi3K92E none np   19265526
Actin organization and cell morphology (3) Pi3K92E none np   19265526
Actin organization and cell morphology (4) Pi3K92E none np   19265526
Actin organization and cell morphology (5) Pi3K92E none np   19265526
Actin organization and cell morphology (6) Pi3K92E none np   19265526
Vaccinia virus infection Pi3K92E none sp   20585561
Hippo pathway regulation Pi3K92E none 0.75   23263283
Glycosylation regulation (1) Pi3K92E none sp   21203496

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