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Gene : Rab5 D. melanogaster

DB identifier  ? FBgn0014010 Secondary Identifier  ? CG3664
Name  ? Rab5 Source  FlyBase
  • synonyms:
  • DmRab5,
  • FBgn0022048,
  • l(2)k08232,
  • CG3664,
  • Rab,
  • FBan0003664,
  • BAA88244,
  • FBgn0014010,
  • RAB5,
  • Rab-protein 5,
  • AAF51265,
  • Dm Rab5,
  • DRab5,
  • Rab-5,
  • RAB5a

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55 Alleles

DB identifier Symbol Allele Class Organism
FBal0243285 Rab5[tCH322-97N16]   Drosophila melanogaster
FBal0277130 Rab5[Q88L.Scer\UAS.N.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0283033 Rab5[Scer\UAS.cTa.T:Avic\GFP]   Drosophila melanogaster
FBal0283351 Rab5[T:Disc\RFP-mCherry]   Drosophila melanogaster
FBal0281770 Rab5[N142I.ro]   Drosophila melanogaster
FBal0285603 Rab5[betaTub85D.T:Avic\GFP]   Drosophila melanogaster
FBal0182036 Rab5[e02885]   Drosophila melanogaster
FBal0246443 Rab5[Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0182037 Rab5[d11055]   Drosophila melanogaster
FBal0182038 Rab5[d09675]   Drosophila melanogaster
FBal0064333 Rab5[k08232]   Drosophila melanogaster
FBal0064334 Rab5[k08230]   Drosophila melanogaster
FBal0182035 Rab5[e03041]   Drosophila melanogaster
FBal0215577 Rab5[Scer\UAS.T:Disc\RFP-DsRed2]   Drosophila melanogaster
FBal0241752 Rab5[JF03335]   Drosophila melanogaster
FBal0159942 Rab5[EY10619]   Drosophila melanogaster
FBal0182048 Rab5[00231]   Drosophila melanogaster
FBal0123123 Rab5[Scim]   Drosophila melanogaster
FBal0285868 Rab5[Q88L.Scer\UAS.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0288693 Rab5[T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0244075 Rab5[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0287916 Rab5[Scer\UAS.C.T:Avic\GFP]   Drosophila melanogaster
FBal0182046 Rab5[3]   Drosophila melanogaster
FBal0182034 Rab5[unspecified]   Drosophila melanogaster
FBal0182049 Rab5[+tWa]   Drosophila melanogaster
FBal0182047 Rab5[2] loss of function allele Drosophila melanogaster
FBal0182045 Rab5[4]   Drosophila melanogaster
FBal0263144 Rab5[HMS00147]   Drosophila melanogaster
FBal0190080 Rab5[alphaTub84B.T:Avic\GFP-ECFP]   Drosophila melanogaster
FBal0182039 Rab5[a.fl.Scer\UAS]   Drosophila melanogaster

302 Clones

Secondary Identifier DB identifier
DPiM_GH24702 FBcl0741531
ESG0111d.B21.1_C06 FBcl0000888
ESG0116c.B21_D07 FBcl0002677
ESG0116a.B21_A05 FBcl0002765
ESG0120d.B21_G03 FBcl0009493
EC30737 FBcl0060849
EC35089 FBcl0060853
EP06542 FBcl0073871
EP07842 FBcl0073875
EP15346 FBcl0073929
EN09434 FBcl0090533
GH22603 FBcl0104079
GH26712 FBcl0104093
GH28615 FBcl0104105
GH28362 FBcl0104107
GH28628 FBcl0104109
GH15713 FBcl0104133
GH21777 FBcl0104135
GH24702 FBcl0104139
EK208303 FBcl0109200
EK042519 FBcl0109464
EK268652 FBcl0109872
EK092208 FBcl0109888
EK227138 FBcl0109896
EK268721 FBcl0109902
EK102029 FBcl0109912
EK237025 FBcl0109934
EK134228 FBcl0109936
EK153451 FBcl0109942
EK267413 FBcl0109950

16 Exons

DB identifier Symbol
FBgn0014010:8 Rab5:8
FBgn0014010:7 Rab5:7
FBgn0014010:6 Rab5:6
FBgn0014010:5 Rab5:5
FBgn0014010:3 Rab5:3
FBgn0014010:2 Rab5:2
FBgn0014010:14 Rab5:14
FBgn0014010:4 Rab5:4
FBgn0014010:12 Rab5:12
FBgn0014010:9 Rab5:9
FBgn0014010:16 Rab5:16
FBgn0014010:15 Rab5:15
FBgn0014010:13 Rab5:13
FBgn0014010:11 Rab5:11
FBgn0014010:1 Rab5:1
FBgn0014010:10 Rab5:10

9 Transcripts

DB identifier Gene
FBtr0330670 Rab5
FBtr0077798 Rab5
FBtr0330669 Rab5
FBtr0077795 Rab5
FBtr0077796 Rab5
FBtr0077793 Rab5
FBtr0330668 Rab5
FBtr0077794 Rab5
FBtr0077797 Rab5

18 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0077798-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0077793-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0077794-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0077795-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0077796-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0077797-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330668-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330669-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330670-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077798-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077793-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077794-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077795-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077796-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077797-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330668-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330669-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330670-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
33418 NCBI Entrez Gene identifiers FBgn0014010
59646 BioGRID FBgn0014010

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 4053.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 3597.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 3475.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 3688.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 3509.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 4186.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 4871.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3288.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 3271.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 5655.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 5183.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 3243.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 4581.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 4230.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 5395.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 3529.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 5600.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 5417.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 6268.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 5446.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 4270.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3075.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2991.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2836.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 3075.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6395.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 4116.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2012.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2613.0
FBgn0014010 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 3299.0

16 Introns

DB identifier
Organism . Name
intron_FBgn0014010:9_FBgn0014010:7 Drosophila melanogaster
intron_FBgn0014010:7_FBgn0014010:6 Drosophila melanogaster
intron_FBgn0014010:6_FBgn0014010:5 Drosophila melanogaster
intron_FBgn0014010:5_FBgn0014010:3 Drosophila melanogaster
intron_FBgn0014010:3_FBgn0014010:2 Drosophila melanogaster
intron_FBgn0014010:13_FBgn0014010:7 Drosophila melanogaster
intron_FBgn0014010:11_FBgn0014010:7 Drosophila melanogaster
intron_FBgn0014010:3_FBgn0014010:1 Drosophila melanogaster
intron_FBgn0014010:12_FBgn0014010:7 Drosophila melanogaster
intron_FBgn0014010:8_FBgn0014010:7 Drosophila melanogaster
intron_FBgn0014010:14_FBgn0014010:7 Drosophila melanogaster
intron_FBgn0014010:5_FBgn0014010:4 Drosophila melanogaster
intron_FBgn0014010:4_FBgn0014010:2 Drosophila melanogaster
intron_FBgn0014010:16_FBgn0014010:7 Drosophila melanogaster
intron_FBgn0014010:15_FBgn0014010:7 Drosophila melanogaster
intron_FBgn0014010:10_FBgn0014010:7 Drosophila melanogaster

40 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Rab5 none 0.791835917   19067489
Lipid storage Rab5 none 0.392103036   19067489
Chlamydia caviae infection Rab5 Decreased Chlamydia caviae infection np   17967059
Drosophila C virus infection Rab5 Drosophila C virus replication down np   17040126
Intracellular Listeria monocytogenes infection Rab5 Decreased GFP protein expression strong   16020693
L. monocytogenes infection Rab5 Fewer infected cells, less vacuolar escape ***   16157870
Wnt signaling Rab5 Increased Wnt reporter activity 4.4   15817814
Mycobacterial infection (1) - M. fortuitum infection Rab5 Decreased M. fortuitum intracellular infection 10.6 measurement after 3 days 16020694
Mycobacterial infection (2) - E. coli phagocytosis Rab5 Decreased E. coli phagocytosis np   16020694
Cell size and cell-cycle regulation (1) Rab5 none sp   16496002
Dendrite pattern formation Rab5 none np   16547170
P. aeruginosa infection Rab5 P. aeruginosa invasion decreased np   18369477
Influenza replication Rab5 Decreased Influenza replication -3.88/-2.63   18615016
Mitochondrial biogenesis and function Rab5 Decreased mitochondrial citrate synthase activity 0.388   18042644
Muscle morphogenesis and function (1) Rab5 Lethal np   20220848
Muscle morphogenesis and function (2) Rab5 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) Rab5 Developmentally lethal 0   21074052
Heat nociception (1) Rab5 Developmentally lethal -1.17   21074052
Heart development and function (1) Rab5 Pupal lethal 0   20371351
Serratia marcescens infection (1) Rab5 Decreased viability after Serratia marcescens infection -1.6   19520911
Serratia marcescens infection (1) Rab5 none -1.25925925925925   19520911
Notch pathway regulation (4) Rab5 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) Rab5 Completely lethal (pupal) sp   19363474
Notch pathway regulation (1) Rab5 Upregulation of Notch pathway np   20493818
Notch pathway regulation (3) Rab5 Only lethal with Notch np   20493818
Adiposity regulation (1) Rab5 none -0.438   20074523
Adiposity regulation (1) Rab5 none -0.31   20074523
RTK-Ras-ERK pathway regulation (1) Rab5 none 0.17 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Rab5 Decreased ERK phosphorylation after EGF stimulation -6 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Rab5 Decreased ERK phosphorylation after sSpitz and EGF stimulation -1.97 30 minutes sSpitz stimulation 22028469

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