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Gene : Pen D. melanogaster

DB identifier  ? FBgn0011823 Secondary Identifier  ? CG4799
Name  ? Pendulin Source  FlyBase
  • synonyms:
  • OHO31,
  • i,
  • l(2)144/1,
  • Importin-alpha,
  • pen-2,
  • importin alpha2/pendulin,
  • IMPalpha2,
  • CG4799,
  • bs29g06.y1,
  • l(2)k14401,
  • alpha-importin,
  • alpha2,
  • DPend,
  • Imp-alpha2,
  • 2.1,
  • pendulin,
  • FBgn0014274,
  • FBgn0011823,
  • Importin alpha2,
  • Importin-a2,
  • Kap-alpha2,
  • Dimp-alpha2,
  • Kpna2,
  • Importin alpha,
  • oho-31,
  • FBgn0026803,
  • FBgn0044610,
  • Dalpha2,
  • pen,
  • imp alpha2,
  • FBan0004799,
  • Importin-alpha2,
  • Rch1,
  • Kap alpha2,
  • anon-WO0140519.258,
  • alphaKap2,
  • alpha2A-Kap

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36 Alleles

DB identifier Symbol Allele Class Organism
FBal0243282 Pen[tCH322-08M17]   Drosophila melanogaster
FBal0281186 Pen[GL01483]   Drosophila melanogaster
FBal0218920 Pen[DG08110]   Drosophila melanogaster
FBal0156085 Pen[EY03523b]   Drosophila melanogaster
FBal0182293 Pen[d07004]   Drosophila melanogaster
FBal0182294 Pen[c05212]   Drosophila melanogaster
FBal0137395 Pen[k14401a]   Drosophila melanogaster
FBal0160028 Pen[EY09095]   Drosophila melanogaster
FBal0089574 Pen[D10]   Drosophila melanogaster
FBal0061690 Pen[D3]   Drosophila melanogaster
FBal0061691 Pen[D14]   Drosophila melanogaster
FBal0061692 Pen[144:1.3]   Drosophila melanogaster
FBal0061693 Pen[144:1.23]   Drosophila melanogaster
FBal0176053 Pen[-UTR.Scer\UAS.P\T]   Drosophila melanogaster
FBal0137398 Pen[S56A.Scer\UAS.P\T]   Drosophila melanogaster
FBal0141598 Pen[Scer\UAS.cGa]   Drosophila melanogaster
FBal0137396 Pen[Scer\UAS.cMa]   Drosophila melanogaster
FBal0137397 Pen[Scer\UAS.P\T.cMa]   Drosophila melanogaster
FBal0232270 Pen[KK103295]   Drosophila melanogaster
FBal0208046 Pen[GD10665]   Drosophila melanogaster
FBal0242354 Pen[JF02772]   Drosophila melanogaster
FBal0228393 Pen[UM-8043-3]   Drosophila melanogaster
FBal0228394 Pen[NP1205]   Drosophila melanogaster
FBal0228395 Pen[NP6315]   Drosophila melanogaster
FBal0228396 Pen[NP6333]   Drosophila melanogaster
FBal0228397 Pen[5-HA-1719]   Drosophila melanogaster
FBal0228398 Pen[5-HA-2203]   Drosophila melanogaster
FBal0228399 Pen[5-HA-2204]   Drosophila melanogaster
FBal0228400 Pen[5-HA-2207]   Drosophila melanogaster
FBal0228401 Pen[5-HA-2210]   Drosophila melanogaster

260 Clones

Secondary Identifier DB identifier
106326 FBcl0408004
Dmel_neb_014201_0367_0741 FBcl0373626
Dmel_dig_013976_0713_2170 FBcl0373627
Dmel_dig_007031_0708_2404 FBcl0373628
Dmel_neb_012150_0198_1167 FBcl0373629
Dmel_neb_009025_0141_1263 FBcl0373630
Dmel_neb_009563_0114_0479 FBcl0373631
Dmel_dig_008390_0708_3032 FBcl0373633
Dmel_neb_015107_0389_2504 FBcl0373632
Dmel_neb_011246_0632_1893 FBcl0373634
Dmel_neb_011293_0401_1786 FBcl0373637
Dmel_neb_010809_0439_2203 FBcl0373635
Dmel_neb_010412_0821_2751 FBcl0373636
Dmel_neb_013505_0848_1927 FBcl0373638
Dmel_neb_012641_0946_2106 FBcl0373639
Dmel_dig_010358_0674_3250 FBcl0373641
Dmel_dig_017378_0601_3403 FBcl0373640
Dmel_dig_016491_0586_3246 FBcl0373642
Dmel_dig_002900_0589_2441 FBcl0373643
Dmel_dig_004137_0657_1124 FBcl0373644
Dmel_dig_010872_0708_1879 FBcl0373645
Dmel_dig_015666_0668_0725 FBcl0373646
UUGC0407 FBcl0001211
EK294956 FBcl0029690
EK209425 FBcl0029708
EK059407 FBcl0029726
EK200059 FBcl0029742
EK054106 FBcl0029760
EK231828 FBcl0029868
EK258704 FBcl0029888

5 Exons

DB identifier Symbol
FBgn0011823:1 Pen:1
FBgn0011823:2 Pen:2
FBgn0011823:3 Pen:3
FBgn0011823:4 Pen:4
FBgn0011823:5 Pen:5

1 Transcripts

DB identifier Gene
FBtr0079937 Pen

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0079937-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079937-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34338 NCBI Entrez Gene identifiers FBgn0011823
60430 BioGRID FBgn0011823

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3926.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 3762.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 3657.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 3871.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 4158.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 6154.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1411.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3748.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 5763.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 4291.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 3621.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2776.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 3424.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 6755.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 5256.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 3059.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3578.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 3899.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 6618.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 3665.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 4036.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3707.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2845.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2152.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 3652.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 8990.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 5416.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 4601.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2838.0
FBgn0011823 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2119.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0011823:1_FBgn0011823:2 Drosophila melanogaster
intron_FBgn0011823:2_FBgn0011823:3 Drosophila melanogaster
intron_FBgn0011823:3_FBgn0011823:4 Drosophila melanogaster
intron_FBgn0011823:4_FBgn0011823:5 Drosophila melanogaster

19 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Pen none 0.015755915   19067489
Lipid storage Pen none -0.741762286   19067489
Cell size and cell-cycle regulation (1) Pen none sp   16496002
Microtubule assembly and organization Pen none np   18463163
Muscle morphogenesis and function (1) Pen none np   20220848
Muscle morphogenesis and function (1) Pen none np   20220848
Heat nociception (1) Pen Increased noxious heat avoidance 2.82   21074052
Heat nociception (1) Pen none -0.77   21074052
Heart development and function (1) Pen none 1   20371351
Serratia marcescens infection (1) Pen none 0.932432432432432   19520911
Notch pathway regulation (4) Pen none 0   19363474
Notch pathway regulation (4) Pen none 0   19363474
Notch induced transcription Pen none 2.6434 without Notch stimulation 20959007
Notch induced transcription Pen none 1.0523 N(delta)ecn Notch stimulation 20959007
Notch induced transcription Pen Downregulation of Notch pathway after Notch stimulation -2.7008 N(delta)ecn Notch stimulation 20959007
Adiposity regulation (1) Pen none -0.074   20074523
Wnt proteins secretion Pen none -0.5   22094269
Hippo pathway regulation Pen none -0.43   23263283
Glycosylation regulation (1) Pen Lethal np   21203496

0 Submissions