modENCODE |  Help |  blog

Gene : Pak D. melanogaster

DB identifier  ? FBgn0014001 Secondary Identifier  ? CG10295
Name  ? PAK-kinase Source  FlyBase
  • synonyms:
  • FBan0010295,
  • PAK kinase,
  • FBgn0037437,
  • FBgn0014001,
  • DPak1,
  • PAK,
  • P21-activating kinase,
  • DPAK,
  • p21- activated kinase,
  • p21-associated kinase,
  • PAK1,
  • DmPAK1,
  • CG10295,
  • p-21 activated kinase,
  • p21 activated kinase,
  • PAK2,
  • P21-activated kinase,
  • Pak1 kinase,
  • p65[PAK],
  • p21-activated serine/threonine kinase,
  • D-Pak

Sequence Feature Displayer

Publication Counts Displayer

Genomics

Gene Ontology Displayer

Homologue Displayer

Mod Mine G Browse Displayer

Overlapping Features Displayer

Regulatory Regions Displayer

53 Alleles

DB identifier Symbol Allele Class Organism
FBal0243281 Pak[tCH322-05M18]   Drosophila melanogaster
FBal0240285 Pak[HM05156]   Drosophila melanogaster
FBal0283079 Pak[Scer\UAS.T:SV5\V5]   Drosophila melanogaster
FBal0182353 Pak[c05029]   Drosophila melanogaster
FBal0182354 Pak[c03088]   Drosophila melanogaster
FBal0182352 Pak[d10699]   Drosophila melanogaster
FBal0182350 Pak[f00999]   Drosophila melanogaster
FBal0182351 Pak[e00352]   Drosophila melanogaster
FBal0160052 Pak[KG09612]   Drosophila melanogaster
FBal0288681 Pak[RBD.sqh.T:Avic\GFP]   Drosophila melanogaster
FBal0288682 Pak[Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0243985 Pak[Scer\UAS.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0098337 Pak[GMR.T:Myr-Src64B]   Drosophila melanogaster
FBal0098335 Pak[K459A.GMR.T:Myr-Src64B]   Drosophila melanogaster
FBal0147693 Pak[Scer\UAS.T:Myr-Src64B]   Drosophila melanogaster
FBal0098347 Pak[1]   Drosophila melanogaster
FBal0098332 Pak[hs.PH]   Drosophila melanogaster
FBal0098333 Pak[L115F.GMR]   Drosophila melanogaster
FBal0098334 Pak[K459A.GMR]   Drosophila melanogaster
FBal0098336 Pak[H91L.H94L.GMR]   Drosophila melanogaster
FBal0098338 Pak[GMR.PH]   Drosophila melanogaster
FBal0098352 Pak[+tT2]   Drosophila melanogaster
FBal0098331 Pak[unspecified]   Drosophila melanogaster
FBal0098344 Pak[4]   Drosophila melanogaster
FBal0098345 Pak[3]   Drosophila melanogaster
FBal0098343 Pak[5]   Drosophila melanogaster
FBal0098350 Pak[11] amorphic allele - genetic evidence Drosophila melanogaster
FBal0098339 Pak[9]   Drosophila melanogaster
FBal0117676 Pak[21]   Drosophila melanogaster
FBal0098341 Pak[7]   Drosophila melanogaster

69 Clones

Secondary Identifier DB identifier
EK250853 FBcl0027162
EK174223 FBcl0027172
EK181255 FBcl0027182
EK058548 FBcl0027194
EK276153 FBcl0027314
EK176719 FBcl0027324
EK040234 FBcl0027334
EK209329 FBcl0027344
EK176702 FBcl0027356
EK113023 FBcl0027366
EK307925 FBcl0027376
EK250154 FBcl0027386
EK118634 FBcl0027418
bs80g11 FBcl0047485
EP17024 FBcl0075077
EN12902 FBcl0091343
GH14822 FBcl0126357
LD18689 FBcl0159409
LD02355 FBcl0159411
LD20767 FBcl0159442
LD11586 FBcl0159446
LD15656 FBcl0159450
LD14209 FBcl0159451
LD03311 FBcl0159453
LD03761 FBcl0159455
LD20773 FBcl0159462
LD20709 FBcl0159479
LD20818 FBcl0159498
RE43055 FBcl0224983
RE15858 FBcl0225072

16 Exons

DB identifier Symbol
FBgn0014001:1 Pak:1
FBgn0014001:7 Pak:7
FBgn0014001:8 Pak:8
FBgn0014001:9 Pak:9
FBgn0014001:10 Pak:10
FBgn0014001:12 Pak:12
FBgn0014001:13 Pak:13
FBgn0014001:15 Pak:15
FBgn0014001:2 Pak:2
FBgn0014001:5 Pak:5
FBgn0014001:6 Pak:6
FBgn0014001:4 Pak:4
FBgn0014001:11 Pak:11
FBgn0014001:14 Pak:14
FBgn0014001:3 Pak:3
FBgn0014001:16 Pak:16

9 Transcripts

DB identifier Gene
FBtr0081716 Pak
FBtr0334543 Pak
FBtr0081714 Pak
FBtr0334542 Pak
FBtr0081715 Pak
FBtr0334539 Pak
FBtr0334540 Pak
FBtr0334541 Pak
FBtr0334544 Pak

18 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0081714-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0081715-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0081716-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334539-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334540-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334541-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334542-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334543-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334544-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0081714-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0081715-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0081716-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334539-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334540-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334541-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334542-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334543-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334544-3-prime-utr Drosophila melanogaster

Interactions

Cytoscape Network Displayer

 

Other

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
44039 NCBI Entrez Gene identifiers FBgn0014001
68794 BioGRID FBgn0014001

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3293.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2928.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1287.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2017.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 3536.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2021.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3101.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2442.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2196.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2900.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2162.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1576.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 3075.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2141.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2272.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2297.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1907.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2042.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2308.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2024.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2335.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2042.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2202.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2932.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1685.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 4841.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 4062.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2469.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1921.0
FBgn0014001 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1759.0

16 Introns

DB identifier
Organism . Name
intron_FBgn0014001:5_FBgn0014001:7 Drosophila melanogaster
intron_FBgn0014001:7_FBgn0014001:8 Drosophila melanogaster
intron_FBgn0014001:8_FBgn0014001:9 Drosophila melanogaster
intron_FBgn0014001:9_FBgn0014001:10 Drosophila melanogaster
intron_FBgn0014001:10_FBgn0014001:12 Drosophila melanogaster
intron_FBgn0014001:12_FBgn0014001:13 Drosophila melanogaster
intron_FBgn0014001:13_FBgn0014001:15 Drosophila melanogaster
intron_FBgn0014001:3_FBgn0014001:7 Drosophila melanogaster
intron_FBgn0014001:10_FBgn0014001:11 Drosophila melanogaster
intron_FBgn0014001:11_FBgn0014001:13 Drosophila melanogaster
intron_FBgn0014001:13_FBgn0014001:16 Drosophila melanogaster
intron_FBgn0014001:6_FBgn0014001:7 Drosophila melanogaster
intron_FBgn0014001:2_FBgn0014001:7 Drosophila melanogaster
intron_FBgn0014001:1_FBgn0014001:7 Drosophila melanogaster
intron_FBgn0014001:4_FBgn0014001:7 Drosophila melanogaster
intron_FBgn0014001:13_FBgn0014001:14 Drosophila melanogaster

36 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Pak none -0.021682578   19067489
Lipid storage Pak none -0.017369488   19067489
Lipid storage Pak none -0.442033298   19067489
Lipid storage Pak none -1.621569451   19067489
Cell morphology Pak Morphology np   14527345
Cell cycle regulation (1) Pak none np   15616552
Cell cycle regulation (2) Pak none np   15616552
Cell size and cell-cycle regulation (1) Pak none sp   16496002
Cell size and cell-cycle regulation (1) Pak none sp   16496002
Cell size and cell-cycle regulation (1) Pak none sp   16496002
CD4 regulation by human immunodeficiency virus Type 1 Nef (HIV-1 Nef) Pak none 2.6   17267500
C. trachomatis infection Pak C. trachomatis infection down np   18369471
P. aeruginosa infection Pak P. aeruginosa invasion decreased np   18369477
Mutant human huntingtin aggregation Pak Increased mutant human huntingtin aggregation 1.5 - 2   19789644
Heat nociception (1) Pak none -1.17   21074052
Heart development and function (1) Pak none 1   20371351
Serratia marcescens infection (1) Pak none -0.623529411764705   19520911
Notch pathway regulation (4) Pak none 0   19363474
Adiposity regulation (1) Pak none 1.006   20074523
Blood cell homeostasis regulation (1) Pak Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) Pak none np   20540764
Blood cell homeostasis regulation (3) Pak Increased melanotic mass formation 24   20540764
Blood cell homeostasis regulation (4) Pak none 0   20540764
Blood cell homeostasis regulation (5) Pak Lethal np   20540764
Blood cell homeostasis regulation (6) Pak none 4   20540764
Blood cell homeostasis regulation (7) Pak none 0   20540764
Blood cell homeostasis regulation (8) Pak none 0   20540764
Actin organization and cell morphology (1) Pak none np   19265526
Actin organization and cell morphology (2) Pak none np   19265526
Actin organization and cell morphology (3) Pak none np   19265526

0 Submissions