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Gene : Sin3A D. melanogaster

DB identifier  ? FBgn0022764 Secondary Identifier  ? CG8815
Name  ? Sin3A Source  FlyBase
  • synonyms:
  • ESTS:159A11T,
  • 97/15,
  • SIN3,
  • EY2-9,
  • l(2)k05415,
  • FBgn0024647,
  • ES2-3,
  • dSin3A,
  • FBgn0020289,
  • FBgn0010646,
  • FBan0008815,
  • l(2)08269,
  • SIN3A,
  • 27/3,
  • l(2)k09715,
  • sni3,
  • ld,
  • Enhancer of GMR-sina 2-3,
  • FBgn0015704,
  • 159A11T,
  • l(2)k02703,
  • FBgn0024589,
  • CG8815,
  • dSin3,
  • Sin 3A,
  • FBgn0022764

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63 Alleles

DB identifier Symbol Allele Class Organism
FBal0283225 Sin3A[B9-E]   Drosophila melanogaster
FBal0243674 Sin3A[EK14]   Drosophila melanogaster
FBal0181547 Sin3A[DG25509]   Drosophila melanogaster
FBal0284078 Sin3A[dsRNA.Scer\UAS.cSa]   Drosophila melanogaster
FBal0181543 Sin3A[d07675]   Drosophila melanogaster
FBal0181546 Sin3A[c01023]   Drosophila melanogaster
FBal0181544 Sin3A[d07432]   Drosophila melanogaster
FBal0181545 Sin3A[d04696]   Drosophila melanogaster
FBal0181542 Sin3A[f00798]   Drosophila melanogaster
FBal0060359 Sin3A[k05415]   Drosophila melanogaster
FBal0130602 Sin3A[EP2032]   Drosophila melanogaster
FBal0086751 Sin3A[k07401]   Drosophila melanogaster
FBal0086966 Sin3A[k02703]   Drosophila melanogaster
FBal0119387 Sin3A[EP866]   Drosophila melanogaster
FBal0008136 Sin3A[08269]   Drosophila melanogaster
FBal0130600 Sin3A[EP2580]   Drosophila melanogaster
FBal0094611 Sin3A[k07423a]   Drosophila melanogaster
FBal0094610 Sin3A[k08919]   Drosophila melanogaster
FBal0089082 Sin3A[k09715]   Drosophila melanogaster
FBal0094609 Sin3A[k11222]   Drosophila melanogaster
FBal0130601 Sin3A[EP2387]   Drosophila melanogaster
FBal0249273 Sin3A[MI02109]   Drosophila melanogaster
FBal0192737 Sin3A[EY23351]   Drosophila melanogaster
FBal0248124 Sin3A[HMS00359]   Drosophila melanogaster
FBal0103963 Sin3A[CY886]   Drosophila melanogaster
FBal0128060 Sin3A[xe374]   Drosophila melanogaster
FBal0152187 Sin3A[cPa]   Drosophila melanogaster
FBal0094612 Sin3A[ex4]   Drosophila melanogaster
FBal0155813 Sin3A[dsRNA.cKa]   Drosophila melanogaster
FBal0119386 Sin3A[dQ4]   Drosophila melanogaster

102 Clones

Secondary Identifier DB identifier
ESG0112a.B21.1_G11 FBcl0000656
AT17481 FBcl0018951
AT01632 FBcl0018983
AT28985 FBcl0019015
AT27813 FBcl0019017
AT08704 FBcl0019053
AT11449 FBcl0019055
AT11743 FBcl0019057
EC36918 FBcl0065453
EC31594 FBcl0065455
EP04254 FBcl0079397
EP10142 FBcl0079401
EP08655 FBcl0079405
EP08755 FBcl0079407
EP14117 FBcl0079447
EP17950 FBcl0079905
EK267239 FBcl0083620
EK239008 FBcl0083736
EK294037 FBcl0083838
EK176843 FBcl0083854
EK253906 FBcl0083870
EK044361 FBcl0083930
EK149318 FBcl0083962
EK202019 FBcl0083980
EK186131 FBcl0083994
EK062437 FBcl0084010
EK316739 FBcl0084024
EK164041 FBcl0084042
EK229639 FBcl0084058
EK198031 FBcl0084072

20 Exons

DB identifier Symbol
FBgn0022764:5 Sin3A:5
FBgn0022764:20 Sin3A:20
FBgn0022764:16 Sin3A:16
FBgn0022764:15 Sin3A:15
FBgn0022764:14 Sin3A:14
FBgn0022764:12 Sin3A:12
FBgn0022764:11 Sin3A:11
FBgn0022764:10 Sin3A:10
FBgn0022764:8 Sin3A:8
FBgn0022764:7 Sin3A:7
FBgn0022764:6 Sin3A:6
FBgn0022764:2 Sin3A:2
FBgn0022764:1 Sin3A:1
FBgn0022764:19 Sin3A:19
FBgn0022764:3 Sin3A:3
FBgn0022764:17 Sin3A:17
FBgn0022764:18 Sin3A:18
FBgn0022764:13 Sin3A:13
FBgn0022764:9 Sin3A:9
FBgn0022764:4 Sin3A:4

9 Transcripts

DB identifier Gene
FBtr0087887 Sin3A
FBtr0087890 Sin3A
FBtr0087889 Sin3A
FBtr0303565 Sin3A
FBtr0303566 Sin3A
FBtr0087888 Sin3A
FBtr0339650 Sin3A
FBtr0339651 Sin3A
FBtr0304683 Sin3A

18 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0087887-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0087888-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0087889-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0087890-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303565-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303566-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0304683-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339650-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339651-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087887-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087888-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087889-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087890-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303565-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303566-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0304683-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339650-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339651-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
36382 NCBI Entrez Gene identifiers FBgn0022764
62156 BioGRID FBgn0022764

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2212.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2345.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1614.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1745.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2127.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1284.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2186.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2431.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1748.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2086.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2293.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1877.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2063.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2301.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 3152.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2022.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3051.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1823.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2026.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2003.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2668.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3312.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1870.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1753.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1872.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 5364.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 4477.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3677.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2561.0
FBgn0022764 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2318.0

24 Introns

DB identifier
Organism . Name
intron_FBgn0022764:20_FBgn0022764:16 Drosophila melanogaster
intron_FBgn0022764:16_FBgn0022764:15 Drosophila melanogaster
intron_FBgn0022764:15_FBgn0022764:14 Drosophila melanogaster
intron_FBgn0022764:14_FBgn0022764:12 Drosophila melanogaster
intron_FBgn0022764:12_FBgn0022764:11 Drosophila melanogaster
intron_FBgn0022764:11_FBgn0022764:10 Drosophila melanogaster
intron_FBgn0022764:10_FBgn0022764:8 Drosophila melanogaster
intron_FBgn0022764:8_FBgn0022764:7 Drosophila melanogaster
intron_FBgn0022764:7_FBgn0022764:6 Drosophila melanogaster
intron_FBgn0022764:6_FBgn0022764:2 Drosophila melanogaster
intron_FBgn0022764:2_FBgn0022764:1 Drosophila melanogaster
intron_FBgn0022764:19_FBgn0022764:16 Drosophila melanogaster
intron_FBgn0022764:17_FBgn0022764:16 Drosophila melanogaster
intron_FBgn0022764:20_FBgn0022764:18 Drosophila melanogaster
intron_FBgn0022764:18_FBgn0022764:16 Drosophila melanogaster
intron_FBgn0022764:6_FBgn0022764:3 Drosophila melanogaster
intron_FBgn0022764:3_FBgn0022764:2 Drosophila melanogaster
intron_FBgn0022764:14_FBgn0022764:13 Drosophila melanogaster
intron_FBgn0022764:13_FBgn0022764:11 Drosophila melanogaster
intron_FBgn0022764:6_FBgn0022764:5 Drosophila melanogaster
intron_FBgn0022764:11_FBgn0022764:9 Drosophila melanogaster
intron_FBgn0022764:9_FBgn0022764:8 Drosophila melanogaster
intron_FBgn0022764:6_FBgn0022764:4 Drosophila melanogaster
intron_FBgn0022764:4_FBgn0022764:2 Drosophila melanogaster

35 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Sin3A none 0.169276759   19067489
Lipid storage Sin3A none 0.527839962   19067489
Neural outgrowth Sin3A Decreased GFP np   18604272
ERK signaling Sin3A ERK activation increased strong   17086199
Constitutive protein secretion and Golgi organization (1) Sin3A Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Sin3A none sp   16496002
Heart development and function Sin3A Heart patterning defects, heart maturation defects np   14684833
Dendrite pattern formation Sin3A Increased 1st branch extension, decreased lateral branching np   16547170
Microtubule assembly and organization Sin3A none np   18463163
Combinatorial effect with methyl methanesulphonate (1) Sin3A Synthetic lethal with methyl methanesulphonate sp   19543366
Combinatorial effect with methyl methanesulphonate (2) Sin3A none sp   19543366
Muscle morphogenesis and function (1) Sin3A Lethal np   20220848
Muscle morphogenesis and function (2) Sin3A Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heart development and function (1) Sin3A none 1   20371351
Heart development and function (2) Sin3A none 2.53   20371351
Serratia marcescens infection (1) Sin3A none -1.17647058823529   19520911
Notch pathway regulation (4) Sin3A Bristle morphology defects, notum malformation death sp   19363474
PGN-induced dJNK phosphorylation Sin3A Decreased P-JNK protein expression with PGN -3.42 15 min PGN induction 19893628
Notch induced transcription Sin3A none -1.9489 without Notch stimulation 20959007
Notch induced transcription Sin3A none 1.9354 N(delta)ecn Notch stimulation 20959007
Notch induced transcription Sin3A Upregulation of Notch pathway after Notch stimulation 4.1462 N(delta)ecn Notch stimulation 20959007
Notch pathway regulation (1) Sin3A Downregulation of Notch pathway np   20493818
Notch pathway regulation (2) Sin3A Lethal strong en-GAL4 20493818
Notch pathway regulation (2) Sin3A Downregulation of Notch pathway; adult wing margin: notches sp C96-GAL4 20493818
Notch pathway regulation (2) Sin3A Up- and downregulation of Notch pathway; wing disc NRE:EGFP: up, gap; wing disc myrRFP: reduced; lethal sp en-GAL4 20493818
Notch pathway regulation (3) Sin3A none np   20493818
Adiposity regulation (1) Sin3A none 0.169   20074523
RTK-Ras-ERK pathway regulation (1) Sin3A Decreased ERK phosphorylation after EGF stimulation -1.85 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Sin3A none 0.78 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Sin3A none 0.76 10 minutes sSpitz stimulation 22028469

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