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Gene : Rpn5 D. melanogaster

DB identifier  ? FBgn0028690 Secondary Identifier  ? CG1100
Name  ? Regulatory particle non-ATPase 5 Source  FlyBase
  • synonyms:
  • FBgn0028690,
  • Rpn5,
  • CG1100,
  • FBan0001100,
  • p55

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6 Alleles

DB identifier Symbol Allele Class Organism
FBal0267962 Rpn5[HMS00971]   Drosophila melanogaster
FBal0286775 Rpn5[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286776 Rpn5[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0270697 Rpn5[NIG.1100R]   Drosophila melanogaster
FBal0208410 Rpn5[GD7166]   Drosophila melanogaster
FBal0230962 Rpn5[KK100873]   Drosophila melanogaster

89 Clones

Secondary Identifier DB identifier
EK206225 FBcl0034026
EK150517 FBcl0034060
EK177152 FBcl0034158
EK184158 FBcl0031086
EK112641 FBcl0034816
EK145008 FBcl0035262
EC22034 FBcl0062119
EP11442 FBcl0075279
EP17629 FBcl0075281
GH11341 FBcl0112469
GH01155 FBcl0112675
GH28874 FBcl0112689
GM10234 FBcl0138095
GM06309 FBcl0138103
HL05491 FBcl0149255
LD14565 FBcl0154483
LD07018 FBcl0154513
LD22811 FBcl0167778
LD35284 FBcl0167781
LD27261 FBcl0167849
LD24574 FBcl0167852
LD46215 FBcl0167865
LD35629 FBcl0167888
LD24076 FBcl0167925
LP10086 FBcl0182969
LP01820 FBcl0183009
LP10826 FBcl0183022
LP08851 FBcl0183032
LP11718 FBcl0183083
RE60695 FBcl0204887

4 Exons

DB identifier Symbol
FBgn0028690:1 Rpn5:1
FBgn0028690:2 Rpn5:2
FBgn0028690:3 Rpn5:3
FBgn0028690:4 Rpn5:4

1 Transcripts

DB identifier Gene
FBtr0078629 Rpn5

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0078629-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078629-3-prime-utr Drosophila melanogaster

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74 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40717 NCBI Entrez Gene identifiers FBgn0028690
65922 BioGRID FBgn0028690

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2584.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2646.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2148.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 3100.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2604.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2489.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3878.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2151.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1753.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3951.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 3280.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2076.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2588.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2009.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 3380.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1838.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2985.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2917.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2738.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 3149.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2088.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3954.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2359.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 3132.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2892.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 9094.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 3964.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2499.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1725.0
FBgn0028690 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2020.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0028690:1_FBgn0028690:2 Drosophila melanogaster
intron_FBgn0028690:2_FBgn0028690:3 Drosophila melanogaster
intron_FBgn0028690:3_FBgn0028690:4 Drosophila melanogaster

36 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Rpn5 none -0.065796111   19067489
Lipid storage Rpn5 none -0.026843683   19067489
ERK signaling Rpn5 ERK activation reduced weak   17086199
Constitutive protein secretion and Golgi organization (1) Rpn5 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Rpn5 none sp   16496002
Influenza replication Rpn5 Decreased Influenza replication -0.03/-3.11   18615016
Mitochondrial biogenesis and function Rpn5 Increased mitochondrial citrate synthase activity, decreased viability 1.925   18042644
Lipid storage Rpn5 Smaller sized lipid droplets, more dispersed strong   18408709
Combinatorial effect with methyl methanesulphonate (2) Rpn5 none sp   19543366
Mutant human huntingtin aggregation Rpn5 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Rpn5 Lethal np   20220848
Muscle morphogenesis and function (1) Rpn5 Lethal np   20220848
Muscle morphogenesis and function (2) Rpn5 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) Rpn5 Increased noxious heat avoidance 6.59   21074052
Heat nociception (1) Rpn5 Increased noxious heat avoidance 5.42   21074052
Heat nociception (2) Rpn5 none 34   21074052
Heat nociception (2) Rpn5 none 30.33333333   21074052
Heart development and function (1) Rpn5 none 1   20371351
Serratia marcescens infection (1) Rpn5 none 0.134615384615384   19520911
Notch pathway regulation (4) Rpn5 Notum malformation death 4   19363474
Notch pathway regulation (4) Rpn5 Completely lethal (pupal) sp   19363474
Notch pathway regulation (1) Rpn5 Upregulation of Notch pathway np   20493818
Adiposity regulation (1) Rpn5 Decreased triglyceride expression -0.372   20074523
Adiposity regulation (2) Rpn5 none 0.106   20074523
Adiposity regulation (3) Rpn5 none 0.115   20074523
Adiposity regulation (4) Rpn5 none 0.186   20074523
Adiposity regulation (5) Rpn5 none -0.054   20074523
Blood cell homeostasis regulation (1) Rpn5 none np   20540764
Blood cell homeostasis regulation (2) Rpn5 none np   20540764
Secretory pathway regulation Rpn5 Decreased BiP signal peptide and firefly luciferase fusion protein expression < -2   19942856

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