Genomics
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9 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0241450 | shtd[2] | Drosophila melanogaster | |
| FBal0241451 | shtd[3.gamma] | Drosophila melanogaster | |
| FBal0241453 | shtd[rescue.Scer\UAS] | Drosophila melanogaster | |
| FBal0258831 | shtd[KK100819] | Drosophila melanogaster | |
| FBal0140936 | shtd[1] | Drosophila melanogaster | |
| FBal0278862 | shtd[HMS01744] | Drosophila melanogaster | |
| FBal0287528 | shtd[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0210576 | shtd[GD14150] | Drosophila melanogaster | |
| FBal0198126 | shtd[3] | loss of function allele | Drosophila melanogaster |
11 Clones
| Secondary Identifier | DB identifier |
|---|---|
| DPiM_LD37115 | FBcl0740633 |
| DMG1-chrX.16.031.a | FBcl0361173 |
| EK286045 | FBcl0129248 |
| GM22507 | FBcl0144627 |
| GM29903 | FBcl0144629 |
| LD37115 | FBcl0171688 |
| RP004207999 | FBcl0503575 |
| CK01.14D.F7 | FBcl0435803 |
| 180906 | FBcl0435830 |
| 214565.29 | FBcl0435842 |
| 62021 | FBcl0435848 |
8 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0004391:8 | shtd:8 |
| FBgn0004391:7 | shtd:7 |
| FBgn0004391:6 | shtd:6 |
| FBgn0004391:5 | shtd:5 |
| FBgn0004391:4 | shtd:4 |
| FBgn0004391:3 | shtd:3 |
| FBgn0004391:2 | shtd:2 |
| FBgn0004391:1 | shtd:1 |
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0074077-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0074077-3-prime-utr | Drosophila melanogaster |
Other
53 Pathways
- Mitotic Metaphase and Anaphase,
- Double-Strand Break Repair,
- Regulation of APC/C activators between G1/S and early anaphase,
- Amplification of signal from the kinetochores,
- Mitotic G2-G2/M phases,
- Phosphorylation of the APC/C,
- SCF(Skp2)-mediated degradation of p27/p21,
- ATM mediated response to DNA double-strand break,
- G2/M DNA replication checkpoint,
- Senescence-Associated Secretory Phenotype (SASP),
- Regulation of mitotic cell cycle,
- Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components,
- Homologous Recombination Repair,
- Autodegradation of Cdh1 by Cdh1:APC/C,
- Cyclin A:Cdk2-associated events at S phase entry,
- Homologous recombination repair of replication-independent double-strand breaks,
- APC/C:Cdc20 mediated degradation of Securin,
- APC/C-mediated degradation of cell cycle proteins,
- Cell Cycle, Mitotic,
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A,
- Separation of Sister Chromatids,
- Cellular responses to stress,
- Cell Cycle,
- Mitotic G1-G1/S phases,
- G2/M Transition,
- p53-Independent DNA Damage Response,
- APC/C:Cdc20 mediated degradation of mitotic proteins,
- M Phase,
- Cyclin E associated events during G1/S transition,
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase,
- Mitotic Anaphase,
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1,
- Cyclin A/B1 associated events during G2/M transition,
- Mitotic M-M/G1 phases,
- G2/M Checkpoints,
- Mitotic Spindle Checkpoint,
- Cellular Senescence,
- p53-Independent G1/S DNA damage checkpoint,
- Polo-like kinase mediated events,
- APC/C:Cdc20 mediated degradation of Cyclin B,
- G1/S Transition,
- G2/M DNA damage checkpoint,
- DNA Repair,
- DNA Replication,
- G1/S DNA Damage Checkpoints,
- APC-Cdc20 mediated degradation of Nek2A,
- Inactivation of APC/C via direct inhibition of the APC/C complex,
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal,
- S Phase,
- Cell Cycle Checkpoints,
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins,
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex,
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 32473 | NCBI Entrez Gene identifiers | FBgn0004391 |
| 58826 | BioGRID | FBgn0004391 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
7 Introns
19 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | shtd | none | 1.266656941 | 19067489 | |
| Lipid storage | shtd | none | -1.160707621 | 19067489 | |
| Lipid storage | shtd | none | -0.731476068 | 19067489 | |
| Lipid storage | shtd | none | 1.66557879 | 19067489 | |
| Cell size and cell-cycle regulation (1) | shtd | none | sp | 16496002 | |
| Microtubule assembly and organization | shtd | Abnormal spindle | np | 18463163 | |
| Mutant human huntingtin aggregation | shtd | Increased mutant human huntingtin aggregation | >= 2 | 19789644 | |
| Muscle morphogenesis and function (1) | shtd | none | np | 20220848 | |
| Heat nociception (1) | shtd | Developmentally lethal | 0 | 21074052 | |
| Heart development and function (1) | shtd | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | shtd | none | 0.119047619047619 | 19520911 | |
| Notch pathway regulation (4) | shtd | Bristle morphology defects, notum malformation death | sp | 19363474 | |
| Self-renewal and differentiation in neural stem cells | shtd | GFP aggregates number, GFP aggregates size, neuroblast smaller cell size, neuroblast less large cells, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with smaller neuroblast cell size, neuroblasts smaller, neuroblast underprolifer | sp | 21549331 | |
| Adiposity regulation (1) | shtd | Decreased triglyceride expression | -0.444 | 20074523 | |
| Adiposity regulation (2) | shtd | none | 0.118 | 20074523 | |
| Adiposity regulation (3) | shtd | none | -0.094 | 20074523 | |
| Adiposity regulation (4) | shtd | Decreased triglyceride expression | -0.986 | 20074523 | |
| Adiposity regulation (5) | shtd | none | -0.073 | 20074523 | |
| Hippo pathway regulation | shtd | none | -2.52 | 23263283 |
