Genomics
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43 Alleles
21 Clones
7 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0010269:1 | Dsor1:1 |
| FBgn0010269:3 | Dsor1:3 |
| FBgn0010269:5 | Dsor1:5 |
| FBgn0010269:6 | Dsor1:6 |
| FBgn0010269:2 | Dsor1:2 |
| FBgn0010269:4 | Dsor1:4 |
| FBgn0010269:7 | Dsor1:7 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0071313-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0340120-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0071313-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0340120-3-prime-utr | Drosophila melanogaster |
Other
83 Pathways
- DAP12 signaling,
- Toll Like Receptor 3 (TLR3) Cascade,
- Toll Like Receptor 5 (TLR5) Cascade,
- IRS-related events triggered by IGF1R,
- Toll Like Receptor 7/8 (TLR7/8) Cascade,
- SHC1 events in EGFR signaling,
- Immune System,
- TRIF-mediated TLR3/TLR4 signaling,
- ERK2 activation,
- Signaling Pathways,
- Signaling by ERBB2,
- Signalling to p38 via RIT and RIN,
- Insulin receptor recycling,
- Insulin signaling pathway,
- MyD88:Mal cascade initiated on plasma membrane,
- Prolonged ERK activation events,
- NGF signalling via TRKA from the plasma membrane,
- Toll Like Receptor 2 (TLR2) Cascade,
- Insulin receptor signalling cascade,
- Signaling by PDGF,
- Cytokine Signaling in Immune system,
- ERK activation,
- L1CAM interactions,
- FCERI mediated MAPK activation,
- GRB2 events in ERBB2 signaling,
- MEK activation,
- TRAF6 Mediated Induction of proinflammatory cytokines,
- IRS-related events,
- SHC1 events in ERBB2 signaling,
- MAP kinase activation in TLR cascade,
- Developmental Biology,
- Signalling to ERKs,
- Signaling by FGFR in disease,
- Frs2-mediated activation,
- Signaling by EGFR,
- SOS-mediated signalling,
- SHC1 events in ERBB4 signaling,
- Signaling by ERBB4,
- MyD88-independent cascade,
- Interleukin-2 signaling,
- Downstream signaling of activated FGFR,
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation,
- Activated TLR4 signalling,
- RAF activation,
- Signaling by NGF,
- SHC-related events,
- IGF1R signaling cascade,
- MyD88 dependent cascade initiated on endosome,
- Toll Like Receptor 10 (TLR10) Cascade,
- NCAM signaling for neurite out-growth,
- IRS-mediated signalling,
- MyD88 cascade initiated on plasma membrane,
- GRB2 events in EGFR signaling,
- ARMS-mediated activation,
- Signaling by Interleukins,
- Signaling by EGFR in Cancer,
- Toll Like Receptor 9 (TLR9) Cascade,
- SHC-mediated signalling,
- Signal transduction by L1,
- Signaling by SCF-KIT,
- Axon guidance,
- Toll Like Receptor TLR1:TLR2 Cascade,
- DAP12 interactions,
- Disease,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- Fc epsilon receptor (FCERI) signaling,
- RAF/MAP kinase cascade,
- Signaling by FGFR,
- ERK1 activation,
- Signaling by GPCR,
- RAF phosphorylates MEK,
- Signaling by Leptin,
- FRS2-mediated cascade,
- Toll-Like Receptors Cascades,
- Innate Immune System,
- DINR-mediated activation,
- SHC-related events triggered by IGF1R,
- Downstream signal transduction,
- Signalling to RAS,
- Toll Like Receptor 4 (TLR4) Cascade,
- Insulin receptor mediated signaling,
- Gastrin-CREB signalling pathway via PKC and MAPK,
- Toll Like Receptor TLR6:TLR2 Cascade
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 31872 | NCBI Entrez Gene identifiers | FBgn0010269 |
| 58322 | BioGRID | FBgn0010269 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
6 Introns
32 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Cell size regulation | Dsor1 | Decreased cell size | -2.02 | 19216764 | |
| Lipid storage | Dsor1 | none | 0.467793418 | 19067489 | |
| Lipid storage | Dsor1 | none | -1.222167663 | 19067489 | |
| Lipid storage | Dsor1 | none | 0.416375816 | 19067489 | |
| Lipid storage | Dsor1 | none | 0.359251412 | 19067489 | |
| ERK signaling | Dsor1 | ERK activation reduced | strong | 17086199 | |
| Cell morphology | Dsor1 | Morphology | np | 14527345 | |
| Cell cycle regulation (1) | Dsor1 | none | np | 15616552 | |
| Cell cycle regulation (2) | Dsor1 | none | np | 15616552 | |
| Cell size and cell-cycle regulation (1) | Dsor1 | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | Dsor1 | none | sp | 16496002 | |
| Muscle morphogenesis and function (1) | Dsor1 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | Dsor1 | Lethal | np | 20220848 | |
| Heat nociception (1) | Dsor1 | none | -1.17 | 21074052 | |
| Heart development and function (1) | Dsor1 | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | Dsor1 | none | 0.541176470588235 | 19520911 | |
| Notch pathway regulation (4) | Dsor1 | Completely lethal (pupal) | sp | 19363474 | |
| Notch pathway regulation (4) | Dsor1 | Notum malformation death | 7 | 19363474 | |
| Adiposity regulation (1) | Dsor1 | none | -0.283 | 20074523 | |
| S2 cell spreading | Dsor1 | none | np | 21041442 | |
| Actin organization and cell morphology (1) | Dsor1 | none | np | 19265526 | |
| Actin organization and cell morphology (2) | Dsor1 | none | np | 19265526 | |
| Actin organization and cell morphology (3) | Dsor1 | none | np | 19265526 | |
| Actin organization and cell morphology (4) | Dsor1 | Altered cell morphology | np | 19265526 | |
| Actin organization and cell morphology (5) | Dsor1 | Altered cell morphology | np | 19265526 | |
| Actin organization and cell morphology (6) | Dsor1 | Altered cell morphology | np | 19265526 | |
| Vaccinia virus infection | Dsor1 | none | sp | 20585561 | |
| RTK-Ras-ERK pathway regulation (1) | Dsor1 | Decreased ERK phosphorylation after EGF stimulation | -2.02 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | Dsor1 | Decreased ERK phosphorylation after EGF stimulation | -1.89 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | Dsor1 | Decreased ERK phosphorylation after sSpitz and EGF stimulation | -5.42 | 10 minutes sSpitz stimulation | 22028469 |
