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Gene : lin19 D. melanogaster

DB identifier  ? FBgn0015509 Secondary Identifier  ? CG1877
Name  ? lin-19-like Source  FlyBase
  • synonyms:
  • dCullin,
  • lin 19,
  • dCullin1,
  • dCul-1,
  • dCUL1,
  • Cul1[Ex],
  • Lin-19,
  • Cul-1,
  • Cullin 1,
  • FBgn0022252,
  • Cullin-1,
  • l(2)02074,
  • Cullin,
  • CG1877,
  • Cullin1,
  • l(2)k01207,
  • FBgn0020308,
  • dmCUL1,
  • lin19-like,
  • Q9V312,
  • Lin19,
  • FBgn0015509,
  • lin-19/cul-1,
  • CUL1,
  • FBan0001877

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19 Alleles

DB identifier Symbol Allele Class Organism
FBal0266261 lin19[GL00561]   Drosophila melanogaster
FBal0242116 lin19[HM05197]   Drosophila melanogaster
FBal0159000 lin19[EY11668]   Drosophila melanogaster
FBal0064599 lin19[k01207]   Drosophila melanogaster
FBal0124987 lin19[BG02329]   Drosophila melanogaster
FBal0246104 lin19[16E]   Drosophila melanogaster
FBal0246105 lin19[107D]   Drosophila melanogaster
FBal0141057 lin19[unspecified] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0141058 lin19[EX] loss of function allele Drosophila melanogaster
FBal0287440 lin19[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0209934 lin19[GD9650]   Drosophila melanogaster
FBal0217732 lin19[Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0217733 lin19[KR.Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0288096 lin19[s-489]   Drosophila melanogaster
FBal0227612 lin19[5-HA-1051]   Drosophila melanogaster
FBal0227613 lin19[NP1210]   Drosophila melanogaster
FBal0230938 lin19[KK100827]   Drosophila melanogaster
FBal0238889 lin19[HP25066]   Drosophila melanogaster
FBal0272948 lin19[NIG.1877R]   Drosophila melanogaster

218 Clones

Secondary Identifier DB identifier
IP02132 FBcl0001046
AT05463 FBcl0030543
AT13610 FBcl0030551
AT28749 FBcl0030553
AT05890 FBcl0030555
AT18154 FBcl0030559
AT24157 FBcl0030561
AT02318 FBcl0030563
AT09952 FBcl0030569
AT13475 FBcl0030571
AT23084 FBcl0030575
AT08149 FBcl0030581
AT29731 FBcl0030595
AT10277 FBcl0030707
AT30367 FBcl0030709
AT21493 FBcl0030713
AT30355 FBcl0044779
bs76h08 FBcl0053861
EC35343 FBcl0069475
EC40589 FBcl0069485
EC39789 FBcl0069487
EP03354 FBcl0084957
GH20775 FBcl0130493
GH26024 FBcl0130497
GH08534 FBcl0130511
GH16543 FBcl0130539
EK182323 FBcl0135196
EK306163 FBcl0135206
EK221204 FBcl0135208
EK236519 FBcl0135210

9 Exons

DB identifier Symbol
FBgn0015509:1 lin19:1
FBgn0015509:3 lin19:3
FBgn0015509:6 lin19:6
FBgn0015509:7 lin19:7
FBgn0015509:8 lin19:8
FBgn0015509:2 lin19:2
FBgn0015509:9 lin19:9
FBgn0015509:5 lin19:5
FBgn0015509:4 lin19:4

4 Transcripts

DB identifier Gene
FBtr0088845 lin19
FBtr0088847 lin19
FBtr0088848 lin19
FBtr0088846 lin19

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0088845-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088846-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088847-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0088848-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088845-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088846-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088847-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088848-3-prime-utr Drosophila melanogaster

Interactions

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Other

95 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
35742 NCBI Entrez Gene identifiers FBgn0015509
61606 BioGRID FBgn0015509

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2483.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2144.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1917.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2465.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2540.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1530.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2056.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2379.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1203.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2131.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2387.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1576.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2712.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 3022.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2103.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1921.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2166.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1606.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2861.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1836.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 7259.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1836.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1817.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1536.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1480.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 6258.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 5466.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3410.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2119.0
FBgn0015509 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2759.0

8 Introns

DB identifier
Organism . Name
intron_FBgn0015509:1_FBgn0015509:3 Drosophila melanogaster
intron_FBgn0015509:3_FBgn0015509:6 Drosophila melanogaster
intron_FBgn0015509:6_FBgn0015509:7 Drosophila melanogaster
intron_FBgn0015509:7_FBgn0015509:8 Drosophila melanogaster
intron_FBgn0015509:5_FBgn0015509:6 Drosophila melanogaster
intron_FBgn0015509:2_FBgn0015509:6 Drosophila melanogaster
intron_FBgn0015509:7_FBgn0015509:9 Drosophila melanogaster
intron_FBgn0015509:4_FBgn0015509:6 Drosophila melanogaster

38 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage lin19 none 1.273801427   19067489
Lipid storage lin19 none 1.187855977   19067489
ERK signaling lin19 ERK activation increased weak   17086199
Cell size and cell-cycle regulation (1) lin19 Increased G1 DNA content sp   16496002
Cell size and cell-cycle regulation (2) lin19 none 1.268   16496002
Cell size and cell-cycle regulation (3) lin19 none 452   16496002
Mutant human huntingtin aggregation lin19 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) lin19 Lethal np   20220848
Muscle morphogenesis and function (1) lin19 Lethal np   20220848
Muscle morphogenesis and function (1) lin19 none np   20220848
Muscle morphogenesis and function (3) lin19 none np   20220848
Heat nociception (1) lin19 Developmentally lethal -0.69   21074052
Heart development and function (1) lin19 none 1   20371351
Heart development and function (1) lin19 none 1   20371351
Heart development and function (2) lin19 none 2.42   20371351
Heart development and function (2) lin19 Decreased viability 4.5   20371351
Serratia marcescens infection (1) lin19 none 0.795698924731182   19520911
Notch pathway regulation (4) lin19 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) lin19 none 0   19363474
Notch pathway regulation (4) lin19 Completely lethal (pupal) sp   19363474
G2-M DNA damage checkpoint regulation (2) lin19 Increased histone H3 phosphorylation with doxorubicin 25.72 with doxorubicin 21205937
G2-M DNA damage checkpoint regulation (2) lin19 Increased histone H3 phosphorylation with etoposide 30.47 with etoposide 21205937
G2-M DNA damage checkpoint regulation (2) lin19 Increased histone H3 phosphorylation after X-ray exposure 62.07 X-ray exposure 21205937
G2-M DNA damage checkpoint regulation (2) lin19 Increased histone H3 phosphorylation with bleocin 20.98 with bleocin 21205937
Adiposity regulation (1) lin19 none -0.103   20074523
Blood cell homeostasis regulation (1) lin19 none np   20540764
Blood cell homeostasis regulation (2) lin19 none np   20540764
Blood cell homeostasis regulation (3) lin19 none 0   20540764
Blood cell homeostasis regulation (4) lin19 none 0   20540764
Blood cell homeostasis regulation (5) lin19 none 0   20540764

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