Genomics
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Regulatory Regions Displayer
33 Alleles
163 Clones
4 Exons
DB identifier | Symbol |
---|---|
FBgn0086357:4 | Sec61alpha:4 |
FBgn0086357:3 | Sec61alpha:3 |
FBgn0086357:2 | Sec61alpha:2 |
FBgn0086357:1 | Sec61alpha:1 |
2 UTRs
Class | DB identifier |
Organism . Name |
---|---|---|
FivePrimeUTR | FBtr0079266-5-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0079266-3-prime-utr | Drosophila melanogaster |
Other
13 Pathways
- Immune System,
- Post-Elongation Processing of the Transcript,
- Post-Elongation Processing of Intronless pre-mRNA,
- Adaptive Immune System,
- Metabolism of proteins,
- ER-Phagosome pathway,
- Antigen processing-Cross presentation,
- Translation,
- Gene Expression,
- SRP-dependent cotranslational protein targeting to membrane,
- mRNA Processing,
- Class I MHC mediated antigen processing & presentation,
- Transcription
2 Cross References
Identifier |
Source . Name |
Subject . Primary Identifier |
---|---|---|
33905 | NCBI Entrez Gene identifiers | FBgn0086357 |
60062 | BioGRID | FBgn0086357 |
11 Data Sets
Name | URL |
---|---|
FlyBase data set for Drosophila melanogaster | |
TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
Drosophila 12 Genomes Consortium homology | |
GenomeRNAi data set | |
TreeFam data set | |
Panther data set | |
IntAct interactions data set | |
BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
GO Annotation from FlyBase | |
FlyBase fasta data set for Drosophila melanogaster | |
Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
23 RNAi Results
Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
---|---|---|---|---|---|
Cell size regulation | Sec61alpha | Decreased cell size | -2.66 | 19216764 | |
Lipid storage | Sec61alpha | none | 0.107741449 | 19067489 | |
Lipid storage | Sec61alpha | none | 1.377884087 | 19067489 | |
ERK signaling | Sec61alpha | ERK activation reduced | weak | 17086199 | |
Constitutive protein secretion and Golgi organization (1) | Sec61alpha | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
Constitutive protein secretion and Golgi organization (2) | Sec61alpha | Fused Golgi membranes with endoplasmic reticulum | np | 16452979 | |
Cell size and cell-cycle regulation (1) | Sec61alpha | none | sp | 16496002 | |
Influenza replication | Sec61alpha | Decreased Influenza replication | -4.19/-2.23 | 18615016 | |
Combinatorial effect with methyl methanesulphonate (2) | Sec61alpha | none | sp | 19543366 | |
Muscle morphogenesis and function (1) | Sec61alpha | none | np | 20220848 | |
Heat nociception (1) | Sec61alpha | none | -1.17 | 21074052 | |
Heart development and function (1) | Sec61alpha | none | 1 | 20371351 | |
Serratia marcescens infection (1) | Sec61alpha | none | -1.29 | 19520911 | |
Notch pathway regulation (4) | Sec61alpha | none | 0 | 19363474 | |
Adiposity regulation (1) | Sec61alpha | none | 1.289 | 20074523 | |
RTK-Ras-ERK pathway regulation (1) | Sec61alpha | none | 0.82 | 0 minutes EGF stimulation | 22028469 |
RTK-Ras-ERK pathway regulation (1) | Sec61alpha | none | -0.46 | 10 minutes EGF stimulation | 22028469 |
RTK-Ras-ERK pathway regulation (2) | Sec61alpha | none | 0.31 | 10 minutes sSpitz stimulation | 22028469 |
RTK-Ras-ERK pathway regulation (2) | Sec61alpha | none | 0.91 | 30 minutes sSpitz stimulation | 22028469 |
Wnt proteins secretion | Sec61alpha | none | -0.3 | 22094269 | |
Hippo pathway regulation | Sec61alpha | none | -1.13 | 23263283 | |
Glycosylation regulation (1) | Sec61alpha | none | sp | 21203496 | |
Huntingtin (Htt) aggregates formation | Sec61alpha | Decreased formation of mutant Huntingtin (Httex1-Qn) protein aggregates | np | 20100940 |