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Gene : Srp54 D. melanogaster

DB identifier  ? FBgn0024285 Secondary Identifier  ? CG4602
Name  ? Srp54 Source  FlyBase
  • synonyms:
  • SRp54,
  • p75,
  • anon-EST:Liang-2.16,
  • FBan0004602,
  • CG4602,
  • dSRp54,
  • FBgn0024285,
  • clone 2.16,
  • FBgn0025965

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4 Alleles

DB identifier Symbol Allele Class Organism
FBal0241715 Srp54[HM05224]   Drosophila melanogaster
FBal0214799 Srp54[GD10663]   Drosophila melanogaster
FBal0223145 Srp54[DG02112]   Drosophila melanogaster
FBal0274281 Srp54[NIG.4602R]   Drosophila melanogaster

71 Clones

Secondary Identifier DB identifier
Dmel_dig_002038_0588_2619 FBcl0373548
Dmel_neb_012878_0603_2989 FBcl0373549
Dmel_neb_013913_0078_2283 FBcl0373550
EK234355 FBcl0033678
EK180615 FBcl0033698
EK272354 FBcl0033740
AT30888 FBcl0022693
EK227763 FBcl0031758
EK057534 FBcl0031774
EK010356 FBcl0031794
EK181922 FBcl0033546
EK010529 FBcl0033568
EK277052 FBcl0033590
EK154702 FBcl0033606
EK202548 FBcl0033626
EK284922 FBcl0033646
EK044539 FBcl0033662
EP18864 FBcl0080943
EP08502 FBcl0080949
GH27801 FBcl0105307
LD13325 FBcl0151930
LD44452 FBcl0164279
LD42385 FBcl0164284
LD29830 FBcl0164286
LD27508 FBcl0164287
LD32487 FBcl0164291
LD37410 FBcl0164294
LD21984 FBcl0164295
LD32079 FBcl0164297
LD32541 FBcl0164299

1 Exons

DB identifier Symbol
FBgn0024285:1 Srp54:1

1 Transcripts

DB identifier Gene
FBtr0079875 Srp54

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0079875-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079875-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34312 NCBI Entrez Gene identifiers FBgn0024285
60406 BioGRID FBgn0024285

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1178.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1649.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 929.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 891.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1136.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1040.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1351.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1388.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 924.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2097.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1658.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 744.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1009.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1665.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1028.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1189.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1381.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1253.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1659.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1177.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1143.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1217.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1214.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1093.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 973.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2842.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 3351.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3205.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1928.0
FBgn0024285 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2181.0

0 Introns

18 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Srp54 Decreased lipid droplet area -2.62347207   19067489
Lipid storage Srp54 Decreased lipid droplet area -3.021662374   19067489
ERK signaling Srp54 ERK activation reduced weak   17086199
Alternative splicing Srp54 Alternative Dscam (exon 4 and exon 17) splicing sp   15492211
Hedgehog signaling Srp54 Decreased Hedgehog reporter activity -2.02   16311596
Cell size and cell-cycle regulation (1) Srp54 none sp   16496002
Candida albicans phagocytosis (1) Srp54 none np   16336044
Mutant human huntingtin aggregation Srp54 Decreased mutant human huntingtin aggregation <= -2   19789644
Heart development and function (1) Srp54 none 1   20371351
Hh pathway regulation Srp54 Downregulation of Hh pathway -0.455072929402479   17903264
Hh pathway regulation Srp54 Downregulation of Hh pathway -0.363466590221379   17903264
Self-renewal and differentiation in neural stem cells Srp54 GFP aggregates number, GFP aggregates size, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast underproliferation, lethal sp   21549331
Notch pathway regulation (1) Srp54 Downregulation of Notch pathway np   20493818
RTK-Ras-ERK pathway regulation (1) Srp54 none -0.03 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Srp54 none 0.03 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Srp54 Increased ERK phosphorylation after sSpitz and EGF stimulation 1.59 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Srp54 Increased ERK phosphorylation after sSpitz and EGF stimulation 2.23 10 minutes sSpitz stimulation 22028469
Glycosylation regulation (1) Srp54 none sp   21203496

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