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Gene : Hsf D. melanogaster

DB identifier  ? FBgn0001222 Secondary Identifier  ? CG5748
Name  ? Heat shock factor Source  FlyBase
  • synonyms:
  • FBgn0001222,
  • CG5748,
  • heat shock transcription factor,
  • HSF,
  • D-HSF,
  • DmHSF,
  • dHSFa,
  • dHSF,
  • HSFa,
  • heat shock transcription factor 1,
  • Dm-Hsf,
  • DmHSFa,
  • FBgn0010529,
  • Heat-Shock Factor,
  • heat shock factor,
  • FBgn0020929,
  • FBan0005748,
  • heat-shock transcription factor,
  • HSF1,
  • l(2)03091

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97 Alleles

DB identifier Symbol Allele Class Organism
FBal0220760 Hsf[JF02415]   Drosophila melanogaster
FBal0283600 Hsf[Scer\UAS.P\T.wt]   Drosophila melanogaster
FBal0283601 Hsf[dsRNA.Scer\UAS.P\T]   Drosophila melanogaster
FBal0283602 Hsf[S378A.Scer\UAS.P\T]   Drosophila melanogaster
FBal0283603 Hsf[S378D.Scer\UAS.P\T]   Drosophila melanogaster
FBal0283110 Hsf[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0183174 Hsf[c06756]   Drosophila melanogaster
FBal0008015 Hsf[03091]   Drosophila melanogaster
FBal0278608 Hsf[GL00698]   Drosophila melanogaster
FBal0285336 Hsf[Scer\UAS.T:Avic\GFP]   Drosophila melanogaster
FBal0285337 Hsf[Scer\UAS.T:Disc\RFP]   Drosophila melanogaster
FBal0061817 Hsf[MtnA.PZ]   Drosophila melanogaster
FBal0105144 Hsf[cLa]   Drosophila melanogaster
FBal0060644 Hsf[+t8]   Drosophila melanogaster
FBal0061816 Hsf[N338.Act5C]   Drosophila melanogaster
FBal0058686 Hsf[Delta259-371.MtnA]   Drosophila melanogaster
FBal0058667 Hsf[MtnA.PR]   Drosophila melanogaster
FBal0058672 Hsf[136-691.MtnA]   Drosophila melanogaster
FBal0061807 Hsf[Q399L.K400R.L404R.MtnA]   Drosophila melanogaster
FBal0044857 Hsf[1] amorphic allele - genetic evidence Drosophila melanogaster
FBal0029850 Hsf[106-691.MtnA]   Drosophila melanogaster
FBal0061830 Hsf[DeltaNLS.Act5C]   Drosophila melanogaster
FBal0061823 Hsf[Act5C.PZ]   Drosophila melanogaster
FBal0058671 Hsf[153-691.MtnA]   Drosophila melanogaster
FBal0061831 Hsf[DeltaBst.Act5C]   Drosophila melanogaster
FBal0061812 Hsf[N461.Act5C]   Drosophila melanogaster
FBal0058679 Hsf[1-404.MtnA]   Drosophila melanogaster
FBal0058682 Hsf[Delta362-404.MtnA]   Drosophila melanogaster
FBal0061825 Hsf[33C.Act5C]   Drosophila melanogaster
FBal0061811 Hsf[N536.Act5C]   Drosophila melanogaster

38 Clones

Secondary Identifier DB identifier
DPiM_SD02833 FBcl0741895
EK139646 FBcl0036188
EK120246 FBcl0036230
EK148429 FBcl0036250
EK136846 FBcl0036278
EK228441 FBcl0036288
AT01133 FBcl0022115
AT30777 FBcl0022159
EK196046 FBcl0036556
EK208914 FBcl0036588
EK164631 FBcl0036674
LD18486 FBcl0156874
LD09851 FBcl0157017
LD18488 FBcl0157018
LP08787 FBcl0185420
LP06613 FBcl0185525
RE47905 FBcl0215441
RE47840 FBcl0215464
RH18305 FBcl0256805
RH42038 FBcl0256889
RH28630 FBcl0256909
RH12320 FBcl0257212
SD02833 FBcl0282978
SD01572 FBcl0282988
Dmel_neb_009691_0921_0472 FBcl0378151
Dmel_neb_009618_0593_0383 FBcl0378152
Dmel_neb_010745_0588_1285 FBcl0378153
CK01.146B.D4 FBcl0462983
281614 FBcl0462977
34006 FBcl0462973

11 Exons

DB identifier Symbol
FBgn0001222:6 Hsf:6
FBgn0001222:11 Hsf:11
FBgn0001222:9 Hsf:9
FBgn0001222:8 Hsf:8
FBgn0001222:7 Hsf:7
FBgn0001222:5 Hsf:5
FBgn0001222:2 Hsf:2
FBgn0001222:1 Hsf:1
FBgn0001222:10 Hsf:10
FBgn0001222:4 Hsf:4
FBgn0001222:3 Hsf:3

4 Transcripts

DB identifier Gene
FBtr0086782 Hsf
FBtr0110965 Hsf
FBtr0110966 Hsf
FBtr0110964 Hsf

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0110964-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0110965-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0110966-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086782-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0110964-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0110965-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0110966-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086782-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
37068 NCBI Entrez Gene identifiers FBgn0001222
62751 BioGRID FBgn0001222

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1445.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1229.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 978.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1010.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1535.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 766.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1383.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1112.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1223.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2348.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1659.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 796.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 993.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1376.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1405.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1217.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1245.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1774.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1430.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 961.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1793.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1710.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1208.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1496.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1332.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 4168.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2619.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2255.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1676.0
FBgn0001222 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1879.0

14 Introns

DB identifier
Organism . Name
intron_FBgn0001222:11_FBgn0001222:9 Drosophila melanogaster
intron_FBgn0001222:9_FBgn0001222:8 Drosophila melanogaster
intron_FBgn0001222:8_FBgn0001222:7 Drosophila melanogaster
intron_FBgn0001222:7_FBgn0001222:5 Drosophila melanogaster
intron_FBgn0001222:5_FBgn0001222:2 Drosophila melanogaster
intron_FBgn0001222:2_FBgn0001222:1 Drosophila melanogaster
intron_FBgn0001222:11_FBgn0001222:10 Drosophila melanogaster
intron_FBgn0001222:10_FBgn0001222:8 Drosophila melanogaster
intron_FBgn0001222:7_FBgn0001222:6 Drosophila melanogaster
intron_FBgn0001222:6_FBgn0001222:4 Drosophila melanogaster
intron_FBgn0001222:4_FBgn0001222:3 Drosophila melanogaster
intron_FBgn0001222:3_FBgn0001222:2 Drosophila melanogaster
intron_FBgn0001222:5_FBgn0001222:3 Drosophila melanogaster
intron_FBgn0001222:4_FBgn0001222:2 Drosophila melanogaster

19 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Hsf none 0.005301559   19067489
Lipid storage Hsf none 1.8815921   19067489
Cell size and cell-cycle regulation (1) Hsf none sp   16496002
Dendrite pattern formation Hsf none np   16547170
Muscle morphogenesis and function (1) Hsf Lethal np   20220848
Muscle morphogenesis and function (1) Hsf Lethal np   20220848
Muscle morphogenesis and function (3) Hsf none np   20220848
Heat nociception (1) Hsf none -1.17   21074052
Heart development and function (1) Hsf none 1   20371351
Serratia marcescens infection (1) Hsf none 1.16455696202531   19520911
Notch pathway regulation (4) Hsf Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) Hsf Completely lethal (before pupal) sp   19363474
Self-renewal and differentiation in neural stem cells Hsf GFP aggregates number, GFP aggregates size, ganglion mother cell shorter lineages, neuroblast underproliferation, lethal sp   21549331
Pol II elongation Hsf Decreased Hsp70 mRNA expression 5 20 min heat shock 19279664
Notch pathway regulation (1) Hsf Downregulation of Notch pathway np   20493818
Adiposity regulation (1) Hsf none -0.41   20074523
Hippo pathway regulation Hsf none -1.87   23263283
Srp/Lz-induced transcriptional activation Hsf Decreased Srp/Lz-induced transcription -4.42   20368357
Huntingtin (Htt) aggregates formation Hsf Increased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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