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Gene : RpII215 D. melanogaster

DB identifier  ? FBgn0003277 Secondary Identifier  ? CG1554
Name  ? RNA polymerase II 215kD subunit Source  FlyBase
  • synonyms:
  • Pol II CTD,
  • FBan0001554,
  • RNA pol IIo,
  • L5,
  • RNAPII,
  • Pol II[ser2],
  • CTD,
  • Pol IIa,
  • l(1)DF912,
  • Pol II,
  • RpII,
  • Ultrabithorax-like,
  • RNA-polymerase II,
  • RNA polymerase II large subunit,
  • RNA PolI 215,
  • Rpll215,
  • rpII1,
  • polymerase II CTD,
  • Pol IIo,
  • RNAP II,
  • Pol II large subunit CTD,
  • 8WG16,
  • FBgn0026704,
  • RNA PolII,
  • l(1)DC912,
  • Ubl,
  • POL,
  • RNA Pol II,
  • Pol II0[ser2],
  • Pol II large subunit,
  • PolIIo,
  • RNA polymeraseII-215 kd subunit,
  • RPII215,
  • Pol IIo[ser5],
  • l(1)10Ca,
  • CG1554,
  • II,
  • RNApol2,
  • RNA Polymerase II,
  • Pol II Ser5P,
  • FBgn0003277,
  • dRPB1,
  • RNAP,
  • RNA Pol II CTD,
  • FBgn0001616,
  • RNAPII0,
  • Pol-IIa,
  • RNAP II LS,
  • RNApolII,
  • PolII,
  • H5,
  • l(1)G0040,
  • RNA polymerase IIo,
  • RPB1,
  • Pol IIo[Ser2],
  • IIo,
  • Pol II0[ser5],
  • 5,
  • l(1)L5

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180 Alleles

DB identifier Symbol Allele Class Organism
FBal0282695 RpII215[X161]   Drosophila melanogaster
FBal0258826 RpII215[KK100802]   Drosophila melanogaster
FBal0014666 RpII215[9]   Drosophila melanogaster
FBal0030152 RpII215[9rv1-1]   Drosophila melanogaster
FBal0030155 RpII215[9rv12-2]   Drosophila melanogaster
FBal0030156 RpII215[9rv12-5]   Drosophila melanogaster
FBal0030157 RpII215[9rv16-2]   Drosophila melanogaster
FBal0030159 RpII215[9rv18-1]   Drosophila melanogaster
FBal0030160 RpII215[9rv2-3]   Drosophila melanogaster
FBal0030161 RpII215[9rv21-1]   Drosophila melanogaster
FBal0030162 RpII215[9rv22-1]   Drosophila melanogaster
FBal0030163 RpII215[9rv22-2]   Drosophila melanogaster
FBal0030164 RpII215[9rv3-2]   Drosophila melanogaster
FBal0030167 RpII215[9rv38-1]   Drosophila melanogaster
FBal0030168 RpII215[9rv4-1]   Drosophila melanogaster
FBal0266385 RpII215[GL01068]   Drosophila melanogaster
FBal0159878 RpII215[EY06155]   Drosophila melanogaster
FBal0152246 RpII215[G0080]   Drosophila melanogaster
FBal0096850 RpII215[G0040]   Drosophila melanogaster
FBal0014739 RpII215[82]   Drosophila melanogaster
FBal0014740 RpII215[83]   Drosophila melanogaster
FBal0014741 RpII215[84]   Drosophila melanogaster
FBal0014743 RpII215[86]   Drosophila melanogaster
FBal0014744 RpII215[87]   Drosophila melanogaster
FBal0014746 RpII215[89]   Drosophila melanogaster
FBal0014748 RpII215[91]   Drosophila melanogaster
FBal0014749 RpII215[92]   Drosophila melanogaster
FBal0014751 RpII215[94]   Drosophila melanogaster
FBal0014752 RpII215[95]   Drosophila melanogaster
FBal0130788 RpII215[PG124]   Drosophila melanogaster

55 Clones

Secondary Identifier DB identifier
EK103633 FBcl0125852
EK229212 FBcl0125868
EK174916 FBcl0125930
EK112838 FBcl0130568
EK111822 FBcl0130778
EK188418 FBcl0130866
EK257018 FBcl0130906
EK295361 FBcl0130912
EK027743 FBcl0130944
EK292717 FBcl0130950
EK178233 FBcl0130976
EK151504 FBcl0130982
EK166336 FBcl0130992
EK058934 FBcl0130998
EK138324 FBcl0131002
EK037940 FBcl0131010
GM21663 FBcl0144457
LD08817 FBcl0157636
LD31247 FBcl0170289
LD43558 FBcl0171781
LD32579 FBcl0171787
LD46587 FBcl0171788
LD41670 FBcl0171790
RE17843 FBcl0212571
RE30267 FBcl0212780
SD10121 FBcl0277602
SD21011 FBcl0277604
EC055683 FBcl0298806
EC054621 FBcl0298807
EC054106 FBcl0298808

4 Exons

DB identifier Symbol
FBgn0003277:4 RpII215:4
FBgn0003277:3 RpII215:3
FBgn0003277:2 RpII215:2
FBgn0003277:1 RpII215:1

1 Transcripts

DB identifier Gene
FBtr0073542 RpII215

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0073542-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073542-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
32100 NCBI Entrez Gene identifiers FBgn0003277
58510 BioGRID FBgn0003277

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1526.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1323.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1675.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1498.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1625.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 913.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2429.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3593.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 872.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1776.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2418.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1482.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1703.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 694.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2264.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1945.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2244.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2066.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1379.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1363.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1821.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1371.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1983.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2391.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1365.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3727.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 3434.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2933.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1969.0
FBgn0003277 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1652.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0003277:4_FBgn0003277:3 Drosophila melanogaster
intron_FBgn0003277:3_FBgn0003277:2 Drosophila melanogaster
intron_FBgn0003277:2_FBgn0003277:1 Drosophila melanogaster

29 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage RpII215 Increased lipid droplet area 0.102368003   19067489
Lipid storage RpII215 Increased lipid droplet area -1.964235798   19067489
Lipid storage RpII215 Increased lipid droplet area 2.781768424   19067489
Lipid storage RpII215 Increased lipid droplet area 3.444082014   19067489
Neural outgrowth RpII215 Short axons np   18604272
Cytokinesis regulation RpII215 Binucleate cells with decreased viability medium   15547975
Intracellular Listeria monocytogenes infection RpII215 Decreased GFP protein expression moderate   16020693
Constitutive protein secretion and Golgi organization (1) RpII215 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) RpII215 Increased G1 cell size sp   16496002
Cell size and cell-cycle regulation (2) RpII215 none 1.404   16496002
Cell size and cell-cycle regulation (3) RpII215 none 452   16496002
Candida albicans phagocytosis (1) RpII215 none np   16336044
Microtubule assembly and organization RpII215 none np   18463163
Mutant human huntingtin aggregation RpII215 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) RpII215 Lethal np   20220848
Notch pathway regulation (4) RpII215 Completely lethal (pupal) sp   19363474
PGN-induced dJNK phosphorylation RpII215 Increased P-JNK protein expression with PGN 4.52 15 min PGN induction 19893628
G2-M DNA damage checkpoint regulation (2) RpII215 Increased histone H3 phosphorylation with bleocin 47.52 with bleocin 21205937
G2-M DNA damage checkpoint regulation (2) RpII215 Increased histone H3 phosphorylation with doxorubicin 80.22 with doxorubicin 21205937
G2-M DNA damage checkpoint regulation (2) RpII215 Increased histone H3 phosphorylation with etoposide 53.84 with etoposide 21205937
G2-M DNA damage checkpoint regulation (2) RpII215 Increased histone H3 phosphorylation after X-ray exposure 64.83 X-ray exposure 21205937
Notch pathway regulation (1) RpII215 Downregulation of Notch pathway np   20493818
RTK-Ras-ERK pathway regulation (1) RpII215 Increased ERK phosphorylation after EGF stimulation 1.51 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) RpII215 Decreased ERK phosphorylation after EGF stimulation -2.93 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) RpII215 Increased ERK phosphorylation after sSpitz and EGF stimulation 1.81 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) RpII215 Increased ERK phosphorylation after sSpitz and EGF stimulation 5.32 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation RpII215 none 2.04   23263283
Srp/Lz-induced transcriptional activation RpII215 Decreased Srp/Lz-induced transcription -15.36   20368357
Glycosylation regulation (1) RpII215 none sp   21203496

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