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Gene : Vha16-1 D. melanogaster

DB identifier  ? FBgn0262736 Secondary Identifier  ? CG3161
Name  ? Vacuolar H[+] ATPase 16kD subunit 1 Source  FlyBase
  • synonyms:
  • BcDNA:SD02875,
  • FBgn0033078,
  • MRE15,
  • FBgn0044467,
  • ATP6V0C,
  • Vacuolar H[+]-ATPase c subunit,
  • Vha1,
  • FBgn0086547,
  • FBgn0046764,
  • c subunit,
  • EP2372,
  • DucC,
  • ductin, vacuolar H(+)-ATPase subunit C proteolipid,
  • FBgn0011275,
  • FBgn0004145,
  • Vacuolar H[+] ATPase subunit 16-1,
  • CG3161,
  • vha16-1,
  • V-ATPase,
  • FBgn0262736,
  • Vhac,
  • FBgn0015839,
  • Vha16,
  • Vacuolar H[+] ATPase 16kD subunit,
  • FBan0003161,
  • unnamed,
  • Ductin subunit C,
  • mRNA-like ncRNA in embryogenesis 15,
  • Ductin

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50 Alleles

DB identifier Symbol Allele Class Organism
FBal0246369 Vha16-1[P16]   Drosophila melanogaster
FBal0248506 Vha16-1[hfl-37]   Drosophila melanogaster
FBal0283821 Vha16-1[EY00180]   Drosophila melanogaster
FBal0261832 Vha16-1[CPTI002280]   Drosophila melanogaster
FBal0261364 Vha16-1[CPTI100041]   Drosophila melanogaster
FBal0279203 Vha16-1[HMS02171]   Drosophila melanogaster
FBal0152134 Vha16-1[BG02080]   Drosophila melanogaster
FBal0152139 Vha16-1[BG01936]   Drosophila melanogaster
FBal0130535 Vha16-1[EP2302]   Drosophila melanogaster
FBal0147326 Vha16-1[G7]   Drosophila melanogaster
FBal0159549 Vha16-1[EY09974]   Drosophila melanogaster
FBal0181075 Vha16-1[f04567]   Drosophila melanogaster
FBal0230064 Vha16-1[NP3437]   Drosophila melanogaster
FBal0230061 Vha16-1[NP2560]   Drosophila melanogaster
FBal0236237 Vha16-1[KK109332]   Drosophila melanogaster
FBal0123955 Vha16-1[BG01842a]   Drosophila melanogaster
FBal0230060 Vha16-1[NP1231]   Drosophila melanogaster
FBal0212874 Vha16-1[22]   Drosophila melanogaster
FBal0061536 Vha16-1[6]   Drosophila melanogaster
FBal0181078 Vha16-1[d04284]   Drosophila melanogaster
FBal0181077 Vha16-1[d05351]   Drosophila melanogaster
FBal0152141 Vha16-1[BG01447]   Drosophila melanogaster
FBal0181076 Vha16-1[f01516]   Drosophila melanogaster
FBal0123954 Vha16-1[BG02165b]   Drosophila melanogaster
FBal0152133 Vha16-1[BG02082]   Drosophila melanogaster
FBal0061539 Vha16-1[3]   Drosophila melanogaster
FBal0152132 Vha16-1[BG02084]   Drosophila melanogaster
FBal0194411 Vha16-1[GS4009]   Drosophila melanogaster
FBal0061537 Vha16-1[5]   Drosophila melanogaster
FBal0152140 Vha16-1[BG01929]   Drosophila melanogaster

573 Clones

Secondary Identifier DB identifier
ESG016b.E21_C10 FBcl0005629
ESG014c.E21_F06 FBcl0008421
ESG013d.E21_E10 FBcl0010317
bs23f01 FBcl0050865
CK00092 FBcl0059603
EK019462 FBcl0064248
EK201959 FBcl0064268
EK171525 FBcl0064326
EK143402 FBcl0064332
EK120143 FBcl0064342
EK194508 FBcl0064366
EK178416 FBcl0064378
EK202102 FBcl0064382
EK072427 FBcl0064386
EK263528 FBcl0064390
EK202254 FBcl0064396
EK187503 FBcl0064402
EK294524 FBcl0064406
EK118621 FBcl0064412
EK197507 FBcl0064418
EK044257 FBcl0064422
EK223644 FBcl0064426
EK225642 FBcl0064430
EK198943 FBcl0064442
EK271909 FBcl0064446
EK169106 FBcl0064602
EK157643 FBcl0064606
EK156006 FBcl0064628
EK099317 FBcl0064632
EK044431 FBcl0064640

7 Exons

DB identifier Symbol
FBgn0262736:4 Vha16-1:4
FBgn0262736:2 Vha16-1:2
FBgn0262736:1 Vha16-1:1
FBgn0262736:5 Vha16-1:5
FBgn0262736:3 Vha16-1:3
FBgn0262736:7 Vha16-1:7
FBgn0262736:6 Vha16-1:6

4 Transcripts

DB identifier Gene
FBtr0086152 Vha16-1
FBtr0086151 Vha16-1
FBtr0086150 Vha16-1
FBtr0086153 Vha16-1

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0086152-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086153-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086150-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086151-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086152-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086153-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086150-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086151-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
44307 NCBI Entrez Gene identifiers FBgn0262736
68967 BioGRID FBgn0262736

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

6 Introns

DB identifier
Organism . Name
intron_FBgn0262736:4_FBgn0262736:2 Drosophila melanogaster
intron_FBgn0262736:2_FBgn0262736:1 Drosophila melanogaster
intron_FBgn0262736:5_FBgn0262736:3 Drosophila melanogaster
intron_FBgn0262736:3_FBgn0262736:2 Drosophila melanogaster
intron_FBgn0262736:7_FBgn0262736:3 Drosophila melanogaster
intron_FBgn0262736:6_FBgn0262736:3 Drosophila melanogaster

18 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Vha16-1 none -1.871892111   19067489
Lipid storage Vha16-1 none -0.378844558   19067489
Constitutive protein secretion and Golgi organization (1) Vha16-1 Decreased horseradish peroxidase protein expression sp   16452979
Combinatorial effect with methyl methanesulphonate (2) Vha16-1 Synthetic lethal with methyl methanesulphonate sp   19543366
Mutant human huntingtin aggregation Vha16-1 Decreased mutant human huntingtin aggregation <= -2   19789644
Heat nociception (1) Vha16-1 Developmentally lethal -1.17   21074052
Heart development and function (1) Vha16-1 none 1   20371351
Heart development and function (1) Vha16-1 none 1   20371351
Serratia marcescens infection (1) Vha16-1 none -0.375   19520911
Notch pathway regulation (4) Vha16-1 Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) Vha16-1 Notum malformation death 9   19363474
Adiposity regulation (1) Vha16-1 none -0.414   20074523
RTK-Ras-ERK pathway regulation (1) Vha16-1 none 0.75 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Vha16-1 Decreased ERK phosphorylation after EGF stimulation -1.84 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Vha16-1 none -0.66 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Vha16-1 none -0.16 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Vha16-1 Downregulation of Hippo pathway 4.08   23263283
Glycosylation regulation (1) Vha16-1 Decreased Chp protein expression np   21203496

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