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Gene : Ilk D. melanogaster

DB identifier  ? FBgn0028427 Secondary Identifier  ? CG10504
Name  ? Integrin linked kinase Source  FlyBase
  • synonyms:
  • CT29478,
  • Integrin-linked kinase,
  • ILK,
  • FBgn0037062,
  • Integrin Linked Kinase,
  • CG10504,
  • DmILK,
  • FBgn0013568,
  • l(3)78Ca,
  • FBan0010504,
  • FBgn0028427

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31 Alleles

DB identifier Symbol Allele Class Organism
FBal0277810 Ilk[E356K.Scer\UAS]   Drosophila melanogaster
FBal0258396 Ilk[54]   Drosophila melanogaster
FBal0258397 Ilk[Delta178-448.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258398 Ilk[Delta34-177.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258399 Ilk[R208D.R210D.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258400 Ilk[R208D.R210D.Delta34-177.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258401 Ilk[T384A.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258402 Ilk[T384D.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258403 Ilk[Scer\UAS.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258404 Ilk[Delta178-448.Scer\UAS.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258405 Ilk[Delta34-177.Scer\UAS.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258406 Ilk[R208D.R210D.Scer\UAS.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258407 Ilk[R208D.R210D.Delta34-177.Scer\UAS.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258408 Ilk[T384A.Scer\UAS.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258409 Ilk[T384D.Scer\UAS.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258410 Ilk[S176G.T180G.Scer\UAS.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258411 Ilk[S176D.T180D.Scer\UAS.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0258412 Ilk[F436A.Scer\UAS.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0150768 Ilk[ZCL3111]   Drosophila melanogaster
FBal0122089 Ilk[+t9]   Drosophila melanogaster
FBal0122088 Ilk[2]   Drosophila melanogaster
FBal0031864 Ilk[1] amorphic allele - genetic evidence Drosophila melanogaster
FBal0262757 Ilk[GL00288]   Drosophila melanogaster
FBal0122087 Ilk[E359K.Scer\UAS]   Drosophila melanogaster
FBal0122086 Ilk[E359K.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0122085 Ilk[K219M.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0122084 Ilk[P358S.T:Avic\GFP-m6]   Drosophila melanogaster
FBal0122083 Ilk[Scer\UAS.cZa]   Drosophila melanogaster
FBal0122082 Ilk[T:Avic\GFP-m6]   Drosophila melanogaster
FBal0207367 Ilk[GD6996]   Drosophila melanogaster

81 Clones

Secondary Identifier DB identifier
ESG0111d.B21.1_H11 FBcl0000176
bs86b03 FBcl0055197
bs86d03 FBcl0055199
EP05518 FBcl0086035
EK174012 FBcl0126238
EK191946 FBcl0126260
EK281561 FBcl0126788
EK106547 FBcl0126806
EK294623 FBcl0126818
EK184833 FBcl0126948
EK213121 FBcl0126960
EK307150 FBcl0127054
GH23643 FBcl0129003
GH05045 FBcl0129061
LD08711 FBcl0160328
LD02317 FBcl0160340
LD26291 FBcl0175652
LD24671 FBcl0175676
LD33063 FBcl0175693
RE04550 FBcl0228266
RE16314 FBcl0228345
RE17945 FBcl0228347
RE20556 FBcl0228349
RE36868 FBcl0228351
RE19291 FBcl0228352
RE50529 FBcl0228353
RE70344 FBcl0228354
RE33613 FBcl0228364
RE55268 FBcl0228366
RE56450 FBcl0228367

5 Exons

DB identifier Symbol
FBgn0028427:2 Ilk:2
FBgn0028427:1 Ilk:1
FBgn0028427:3 Ilk:3
FBgn0028427:4 Ilk:4
FBgn0028427:5 Ilk:5

2 Transcripts

DB identifier Gene
FBtr0307160 Ilk
FBtr0078305 Ilk

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0078305-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307160-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078305-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0307160-3-prime-utr Drosophila melanogaster

Interactions

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
53573 NCBI Entrez Gene identifiers FBgn0028427
72800 BioGRID FBgn0028427

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1197.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1111.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1128.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1025.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1495.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 293.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 985.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1029.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 696.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1469.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2108.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 942.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 849.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1742.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 476.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1101.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1563.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 545.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1315.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 838.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 798.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 972.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 862.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 671.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 739.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1329.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 789.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 297.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 500.0
FBgn0028427 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 594.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0028427:1_FBgn0028427:3 Drosophila melanogaster
intron_FBgn0028427:3_FBgn0028427:4 Drosophila melanogaster
intron_FBgn0028427:4_FBgn0028427:5 Drosophila melanogaster

22 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Ilk none -0.016880405   19067489
Lipid storage Ilk none 2.467735008   19067489
Cell cycle regulation (1) Ilk All mitotic defects, lagging chromatids, spindle defects sp   15616552
Cell cycle regulation (2) Ilk none np   15616552
Cell size and cell-cycle regulation (1) Ilk none sp   16496002
Cell size and cell-cycle regulation (1) Ilk none sp   16496002
Muscle morphogenesis and function (1) Ilk Lethal np   20220848
Muscle morphogenesis and function (3) Ilk Rounded muscles np   20220848
Heat nociception (1) Ilk none -0.26   21074052
Heart development and function (1) Ilk Embryonic lethal or no offspring 0.5   20371351
Heart development and function (2) Ilk Decreased viability 3.32   20371351
Serratia marcescens infection (1) Ilk none -1.12941176470588   19520911
Notch pathway regulation (4) Ilk none 0   19363474
Adiposity regulation (1) Ilk none 0.255   20074523
Actin organization and cell morphology (1) Ilk none np   19265526
Actin organization and cell morphology (2) Ilk none np   19265526
Actin organization and cell morphology (3) Ilk none np   19265526
Actin organization and cell morphology (4) Ilk none np   19265526
Actin organization and cell morphology (5) Ilk none np   19265526
Actin organization and cell morphology (6) Ilk none np   19265526
Vaccinia virus infection Ilk none sp   20585561
Hippo pathway regulation Ilk none 1.24   23263283

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