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Gene : Rab1 D. melanogaster

DB identifier  ? FBgn0016700 Secondary Identifier  ? CG3320
Name  ? Rab1 Source  FlyBase
  • synonyms:
  • Dm Rab1,
  • dendritic arbor reduction 6,
  • CG3320,
  • O18332,
  • rab1,
  • Rab-protein 1,
  • RAB1a,
  • dar6,
  • AAF55873,
  • DmRab1,
  • DRAB1,
  • FBgn0016700,
  • FBan0003320

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19 Alleles

DB identifier Symbol Allele Class Organism
FBal0265596 Rab1[S147213]   Drosophila melanogaster
FBal0211944 Rab1[CB03450]   Drosophila melanogaster
FBal0159948 Rab1[e01287]   Drosophila melanogaster
FBal0257808 Rab1[HMS01148]   Drosophila melanogaster
FBal0215583 Rab1[12-3-73]   Drosophila melanogaster
FBal0215585 Rab1[unspecified]   Drosophila melanogaster
FBal0215584 Rab1[11-4-72]   Drosophila melanogaster
FBal0150664 Rab1[S073714]   Drosophila melanogaster
FBal0261321 Rab1[CPTI004256]   Drosophila melanogaster
FBal0261322 Rab1[CPTI004394]   Drosophila melanogaster
FBal0083266 Rab1[N124I.Scer\UAS]   Drosophila melanogaster
FBal0156005 Rab1[N124I.T:Sjap\GST]   Drosophila melanogaster
FBal0239309 Rab1[JF02609]   Drosophila melanogaster
FBal0215382 Rab1[Q70L.Scer\UAS.P\T.T:Avic\GFP-YFP]   Drosophila melanogaster
FBal0215381 Rab1[S25N.Scer\UAS.T:Avic\GFP-YFP]   Drosophila melanogaster
FBal0215380 Rab1[Scer\UAS.T:Avic\GFP-YFP]   Drosophila melanogaster
FBal0214707 Rab1[GD10506]   Drosophila melanogaster
FBal0264626 Rab1[MI03612]   Drosophila melanogaster
FBal0273778 Rab1[NIG.3320R]   Drosophila melanogaster

226 Clones

Secondary Identifier DB identifier
ESG011b.E7_H05 FBcl0010881
ESG011b.E21_H05 FBcl0011609
ESG012b.E21.1_F02 FBcl0012581
ESG0119d.B21_A07 FBcl0013493
bs79h12 FBcl0051973
CK01092 FBcl0059779
EC13692 FBcl0067365
EC14872 FBcl0067387
EC27287 FBcl0067401
EK045234 FBcl0073624
EK152631 FBcl0073632
EK087157 FBcl0073638
EK079459 FBcl0073644
EK220559 FBcl0073660
EK294345 FBcl0073668
EK190559 FBcl0073724
EK053147 FBcl0073728
EK264414 FBcl0073744
EK174116 FBcl0073752
EK182305 FBcl0073794
EK282962 FBcl0073798
EK041505 FBcl0073878
EK065239 FBcl0073882
EK256628 FBcl0074708
EK259333 FBcl0074750
EK195151 FBcl0074752
EK207545 FBcl0074822
EK182228 FBcl0074826
EK288726 FBcl0074830
EK176931 FBcl0074832

5 Exons

DB identifier Symbol
FBgn0016700:5 Rab1:5
FBgn0016700:4 Rab1:4
FBgn0016700:3 Rab1:3
FBgn0016700:2 Rab1:2
FBgn0016700:1 Rab1:1

1 Transcripts

DB identifier Gene
FBtr0084104 Rab1

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0084104-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0084104-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42524 NCBI Entrez Gene identifiers FBgn0016700
67494 BioGRID FBgn0016700

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 5974.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 7168.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 3165.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 5071.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 4861.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 3614.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 5286.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 6415.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 5552.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 4528.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 4220.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 3593.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 4529.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 4730.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2362.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2627.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3539.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 3860.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 3519.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 3429.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2635.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3645.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2953.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 4727.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 4911.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3901.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2803.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2670.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2396.0
FBgn0016700 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 3014.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0016700:5_FBgn0016700:4 Drosophila melanogaster
intron_FBgn0016700:4_FBgn0016700:3 Drosophila melanogaster
intron_FBgn0016700:3_FBgn0016700:2 Drosophila melanogaster
intron_FBgn0016700:2_FBgn0016700:1 Drosophila melanogaster

25 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Rab1 none -0.387882617   19067489
Lipid storage Rab1 none 2.497846514   19067489
Cell morphology Rab1 Morphology np   14527345
Cytokinesis regulation Rab1 Binucleate cells weak   15547975
Intracellular Listeria monocytogenes infection Rab1 Decreased GFP protein expression moderate   16020693
L. monocytogenes infection Rab1 Fewer infected cells, less vacuolar escape *   16157870
Constitutive protein secretion and Golgi organization (1) Rab1 Decreased horseradish peroxidase protein expression sp   16452979
Constitutive protein secretion and Golgi organization (2) Rab1 Fused Golgi membranes with endoplasmic reticulum np   16452979
Cell size and cell-cycle regulation (1) Rab1 none sp   16496002
Brucella melitensis infection Rab1 Decreased Brucella melitensis infection 2   18654626
C. trachomatis infection Rab1 C. trachomatis infection down np   18369471
Influenza replication Rab1 Decreased Influenza replication -4.06/-1.98   18615016
Mutant human huntingtin aggregation Rab1 Decreased mutant human huntingtin aggregation <= -2   19789644
Regulated secretory pathway biogenesis (1) Rab1 Increased dVMAT protein cell surface expression 3.8   21149569
Regulated secretory pathway biogenesis (2) Rab1 Increased dVMAT protein cell surface expression np   21149569
Notch pathway regulation (1) Rab1 Downregulation of Notch pathway np   20493818
Secretory pathway regulation Rab1 Decreased BiP signal peptide and firefly luciferase fusion protein expression (-2) - (-1.5)   19942856
RTK-Ras-ERK pathway regulation (1) Rab1 none 0.7 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Rab1 none -1.09 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Rab1 Decreased ERK phosphorylation after sSpitz and EGF stimulation -1.52 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Rab1 none -1.3 10 minutes sSpitz stimulation 22028469
Wnt proteins secretion Rab1 none -0.3   22094269
Hippo pathway regulation Rab1 none -0.38   23263283
Glycosylation regulation (1) Rab1 none sp   21203496
Huntingtin (Htt) aggregates formation Rab1 Decreased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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