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Gene : dome D. melanogaster

DB identifier  ? FBgn0043903 Secondary Identifier  ? CG14226
Name  ? domeless Source  FlyBase
  • synonyms:
  • DOME,
  • FBgn0028267,
  • FBgn0028288,
  • Dome receptor,
  • vsp,
  • verstopft,
  • master of marelle,
  • FBgn0028335,
  • 142932_at,
  • FBgn0028344,
  • CG14226,
  • FBgn0043903,
  • FBgn0019901,
  • DOMELESS,
  • mom,
  • FBgn0028311,
  • l(1)G0468,
  • FBgn0028326,
  • FBan0014226,
  • FBgn0031056,
  • CT33841,
  • l(1)G0217,
  • l(1)G0441,
  • l(1)G0405,
  • anon-18DEb,
  • l(1)G0282,
  • l(1)G0367,
  • l(1)G0218,
  • l(1)G0264,
  • l(1)G0321,
  • FBgn0027236

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52 Alleles

DB identifier Symbol Allele Class Organism
FBal0263460 dome[60441]   Drosophila melanogaster
FBal0260958 dome[dsRNA.Scer\UAS.cCa]   Drosophila melanogaster
FBal0240323 dome[JF01682]   Drosophila melanogaster
FBal0180146 dome[GG01616]   Drosophila melanogaster
FBal0245561 dome[JF01269]   Drosophila melanogaster
FBal0245943 dome[JF01758]   Drosophila melanogaster
FBal0257331 dome[HMS00647]   Drosophila melanogaster
FBal0180145 dome[d09436]   Drosophila melanogaster
FBal0152016 dome[G0383]   Drosophila melanogaster
FBal0257888 dome[HMS01293]   Drosophila melanogaster
FBal0098129 dome[G0282] loss of function allele Drosophila melanogaster
FBal0100303 dome[G0367] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0100280 dome[G0405] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0100259 dome[G0441] loss of function allele Drosophila melanogaster
FBal0100318 dome[G0321] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0100327 dome[G0264] loss of function allele Drosophila melanogaster
FBal0100336 dome[G0218] loss of function allele Drosophila melanogaster
FBal0126401 dome[G0468] loss of function allele Drosophila melanogaster
FBal0126402 dome[G0217] loss of function allele Drosophila melanogaster
FBal0126403 dome[G0199b] loss of function allele Drosophila melanogaster
FBal0128001 dome[5.1] wild-type allele Drosophila melanogaster
FBal0130414 dome[PL100]   Drosophila melanogaster
FBal0130412 dome[PL58]   Drosophila melanogaster
FBal0130413 dome[PL41]   Drosophila melanogaster
FBal0130415 dome[PG5]   Drosophila melanogaster
FBal0130416 dome[PG35]   Drosophila melanogaster
FBal0130417 dome[PG14]   Drosophila melanogaster
FBal0130418 dome[PG125]   Drosophila melanogaster
FBal0147192 dome[KG08434a]   Drosophila melanogaster
FBal0285324 dome[dsRNA.Scer\UAS.cUa]   Drosophila melanogaster

72 Clones

Secondary Identifier DB identifier
DPiM_LD46805 FBcl0741995
AT15805 FBcl0026413
AT27072 FBcl0026415
CK01682 FBcl0059485
EK238848 FBcl0108758
EK238718 FBcl0108770
EK237317 FBcl0108782
EK111759 FBcl0108824
EK185413 FBcl0108906
EK105829 FBcl0108916
EK201251 FBcl0109072
EK271219 FBcl0109084
EK063015 FBcl0109094
EK134952 FBcl0109124
EK229858 FBcl0109546
EK045101 FBcl0109564
EK110437 FBcl0114430
EK218657 FBcl0114794
EK056863 FBcl0114802
EK150138 FBcl0114808
EK291404 FBcl0114820
EK188225 FBcl0124076
GM02606 FBcl0140289
GM13581 FBcl0146548
GM13503 FBcl0146550
LD04367 FBcl0153948
LD18445 FBcl0153971
LD32495 FBcl0167225
LD29548 FBcl0167227
LD38319 FBcl0167233

3 Exons

DB identifier Symbol
FBgn0043903:3 dome:3
FBgn0043903:2 dome:2
FBgn0043903:1 dome:1

1 Transcripts

DB identifier Gene
FBtr0074756 dome

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0074756-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0074756-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
32976 NCBI Entrez Gene identifiers FBgn0043903
59272 BioGRID FBgn0043903

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 440.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 451.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 427.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 271.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 301.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 201.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 544.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 569.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 300.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 543.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 804.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 218.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 504.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 500.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 558.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 511.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 665.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 489.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 541.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 371.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 619.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 550.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 285.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 769.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1074.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2466.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2730.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2391.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1589.0
FBgn0043903 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1217.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0043903:3_FBgn0043903:2 Drosophila melanogaster
intron_FBgn0043903:2_FBgn0043903:1 Drosophila melanogaster

28 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage dome none -1.514955041   19067489
Lipid storage dome none 0.633275033   19067489
ERK signaling dome ERK activation increased weak   17086199
Cell size and cell-cycle regulation (1) dome Decreased G2 DNA content sp   16496002
Cell size and cell-cycle regulation (1) dome none sp   16496002
Cell size and cell-cycle regulation (1) dome none sp   16496002
Cell size and cell-cycle regulation (2) dome none 1.424   16496002
Cell size and cell-cycle regulation (3) dome none 469   16496002
Heart development and function dome Heart patterning defects, heart maturation defects np   14684833
Muscle morphogenesis and function (1) dome none np   20220848
Muscle morphogenesis and function (1) dome none np   20220848
Muscle morphogenesis and function (1) dome none np   20220848
Heat nociception (1) dome none -1.17   21074052
Heat nociception (1) dome none 0.12   21074052
Heart development and function (1) dome none 1   20371351
Heart development and function (1) dome none 1   20371351
Serratia marcescens infection (1) dome none 0.0909090909090909   19520911
Notch pathway regulation (4) dome Notum malformation migration, overproliferation sp   19363474
Notch pathway regulation (4) dome Notum malformation migration, overproliferation sp   19363474
Notch pathway regulation (4) dome Notum malformation migration, overproliferation sp   19363474
PGN-induced dJNK phosphorylation dome Increased P-JNK protein expression with PGN 3.99 15 min PGN induction 19893628
Adiposity regulation (1) dome none -0.547   20074523
Vaccinia virus infection dome none sp   20585561
RTK-Ras-ERK pathway regulation (1) dome Increased ERK phosphorylation after EGF stimulation 1.78 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) dome none -0.68 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) dome none -0.04 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) dome none 0.37 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation dome Upregulation of Hippo pathway -3.23   23263283

0 Submissions