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Gene : Lam D. melanogaster

DB identifier  ? FBgn0002525 Secondary Identifier  ? CG6944
Name  ? Lamin Source  FlyBase
  • synonyms:
  • Dm[[mit]],
  • Lam[[Dm0]],
  • Lamin DmO,
  • jf27,
  • Lamin Dm[[0]],
  • misrouted,
  • l(2)gdh7,
  • Lamin B,
  • FBgn0002525,
  • Lamin Dm0,
  • lamDm0,
  • 2459,
  • lethal(2)25Ec,
  • 74/76,
  • misguided,
  • DM[[O]],
  • lamin D[[0]],
  • l(2)gdh-7,
  • alpha-Lamin,
  • DmO,
  • intermediate filament-like lamina,
  • Dm,
  • l(2)25Ec,
  • lamin A,
  • Lamin D[[o]],
  • Dm[[1]],
  • lamin D[[m]]0,
  • nlam,
  • D5,
  • Dm[[2]],
  • Lamin,
  • LamDm,
  • l(2)04643,
  • LamDm[[o]],
  • FBgn0001930,
  • FBgn0010582,
  • Dm[[0]],
  • Lamin D,
  • LaminDm0,
  • FBan0006944,
  • nuclear lamin,
  • Dm2,
  • CG6944,
  • Dm0,
  • DmLamin,
  • l(2)jf27,
  • Lam(Dm0),
  • LAM,
  • LamDm[[0]],
  • FBgn0014344,
  • n-lamin,
  • B-type Lamin,
  • Lam Dm[[0]],
  • Lamin-B,
  • LaminDm,
  • Dm1,
  • Dm(0),
  • misg

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38 Alleles

DB identifier Symbol Allele Class Organism
FBal0258619 Lam[FB2.0]   Drosophila melanogaster
FBal0266277 Lam[GL00577]   Drosophila melanogaster
FBal0211699 Lam[CB03749]   Drosophila melanogaster
FBal0147816 Lam[G262]   Drosophila melanogaster
FBal0284201 Lam[TRiP.cUa]   Drosophila melanogaster
FBal0245661 Lam[JF01389]   Drosophila melanogaster
FBal0160255 Lam[EY08333]   Drosophila melanogaster
FBal0065070 Lam[P]   Drosophila melanogaster
FBal0008068 Lam[04643] loss of function allele Drosophila melanogaster
FBal0043450 Lam[02459]   Drosophila melanogaster
FBal0260856 Lam[hs.T:Ecol\lacI]   Drosophila melanogaster
FBal0042653 Lam[+t4.2]   Drosophila melanogaster
FBal0182963 Lam[dsRNA.cWa]   Drosophila melanogaster
FBal0065071 Lam[+tLa]   Drosophila melanogaster
FBal0191836 Lam[unspecified]   Drosophila melanogaster
FBal0008355 Lam[sz9]   Drosophila melanogaster
FBal0189595 Lam[14] amorphic allele - genetic evidence Drosophila melanogaster
FBal0182966 Lam[Ari3] loss of function allele Drosophila melanogaster
FBal0008354 Lam[a7]   Drosophila melanogaster
FBal0160254 Lam[dsRNA.cSa]   Drosophila melanogaster
FBal0190395 Lam[9] amorphic allele - genetic evidence Drosophila melanogaster
FBal0008356 Lam[sz18]   Drosophila melanogaster
FBal0182968 Lam[83] loss of function allele Drosophila melanogaster
FBal0182967 Lam[A25] loss of function allele Drosophila melanogaster
FBal0128180 Lam[ex91]   Drosophila melanogaster
FBal0008352 Lam[25A]   Drosophila melanogaster
FBal0182965 Lam[Ari7] loss of function allele Drosophila melanogaster
FBal0182964 Lam[K2] loss of function allele Drosophila melanogaster
FBal0128179 Lam[ex98]   Drosophila melanogaster
FBal0008353 Lam[2]   Drosophila melanogaster

103 Clones

Secondary Identifier DB identifier
EK022314 FBcl0029254
EK222850 FBcl0029468
EK130309 FBcl0029480
EK048044 FBcl0029500
EK057455 FBcl0029528
EK254464 FBcl0029538
EK171113 FBcl0029558
EK102049 FBcl0029576
EK307522 FBcl0029584
EK050033 FBcl0029596
EK071202 FBcl0029606
EK122951 FBcl0029616
EK261718 FBcl0029720
EK198412 FBcl0029736
EK275520 FBcl0029754
EK277501 FBcl0029764
EK200003 FBcl0029786
EK107359 FBcl0029796
EK293933 FBcl0029812
EK113622 FBcl0029880
EK247637 FBcl0029892
EK083819 FBcl0029900
EK115307 FBcl0029910
EK101628 FBcl0029916
EK219658 FBcl0029926
EK225838 FBcl0029934
EK202638 FBcl0029940
EK277459 FBcl0029948
EK161751 FBcl0029960
EK293646 FBcl0029970

6 Exons

DB identifier Symbol
FBgn0002525:3 Lam:3
FBgn0002525:4 Lam:4
FBgn0002525:5 Lam:5
FBgn0002525:6 Lam:6
FBgn0002525:2 Lam:2
FBgn0002525:1 Lam:1

3 Transcripts

DB identifier Gene
FBtr0307059 Lam
FBtr0079100 Lam
FBtr0307058 Lam

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0079100-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307058-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307059-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079100-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0307058-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0307059-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
33782 NCBI Entrez Gene identifiers FBgn0002525
59950 BioGRID FBgn0002525

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 4561.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 5100.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 3555.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 3840.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 3669.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2186.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2801.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3856.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2082.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 6313.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 4547.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1473.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 5757.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 5184.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 4256.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 3999.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 4345.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 3115.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 6815.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 3049.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 4960.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 5766.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 3743.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2671.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1897.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 5793.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 5765.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 6719.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 6408.0
FBgn0002525 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 7895.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0002525:1_FBgn0002525:4 Drosophila melanogaster
intron_FBgn0002525:4_FBgn0002525:5 Drosophila melanogaster
intron_FBgn0002525:5_FBgn0002525:6 Drosophila melanogaster
intron_FBgn0002525:2_FBgn0002525:4 Drosophila melanogaster
intron_FBgn0002525:3_FBgn0002525:4 Drosophila melanogaster

14 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Lam none 0.451776369   19067489
Lipid storage Lam none -1.097334244   19067489
Intracellular Listeria monocytogenes infection Lam Decreased GFP protein expression moderate   16020693
Cell size and cell-cycle regulation (1) Lam none sp   16496002
Brucella melitensis infection Lam Decreased Brucella melitensis infection 21.93   18654626
Muscle morphogenesis and function (1) Lam Lethal np   20220848
Heat nociception (1) Lam none -1.17   21074052
Heart development and function (1) Lam none 1   20371351
Heart development and function (1) Lam none 1   20371351
Notch pathway regulation (4) Lam Loss of bristles, bristle morphology defects, notum malformation death sp   19363474
Notch pathway regulation (4) Lam Loss of bristles, planar polarity defects, lateral inhibition sp   19363474
Muscle assembly and maintenance Lam none np   18359903
S2 cell spreading Lam none np   21041442
Hippo pathway regulation Lam none -0.19   23263283

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