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Gene : twe D. melanogaster

DB identifier  ? FBgn0002673 Secondary Identifier  ? CG4965
Name  ? twine Source  FlyBase
  • synonyms:
  • FBan0004965,
  • Cdc25,
  • Twe,
  • twn,
  • FBgn0002673,
  • l(2)35Fh,
  • CG4965,
  • FBgn0016862,
  • mat(2)synHB5,
  • BG:DS02740.1,
  • TWINE,
  • mat(2)syn[HB5],
  • mat(2)syn-A

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25 Alleles

DB identifier Symbol Allele Class Organism
FBal0266247 twe[GL00547]   Drosophila melanogaster
FBal0257326 twe[HMS00642]   Drosophila melanogaster
FBal0127853 twe[Z0758] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0093757 twe[EP613]   Drosophila melanogaster
FBal0082107 twe[k08310]   Drosophila melanogaster
FBal0286379 twe[Scer\UAS.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0286380 twe[kd.Scer\UAS.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0286381 twe[Scer\UAS.T:Zzzz\Dronpa]   Drosophila melanogaster
FBal0286382 twe[106-180.Scer\UAS.T:Avic\GFP]   Drosophila melanogaster
FBal0035878 twe[+t10]   Drosophila melanogaster
FBal0044430 twe[+t3.7]   Drosophila melanogaster
FBal0127854 twe[betaTub85D.PM]   Drosophila melanogaster
FBal0101121 twe[RN2]   Drosophila melanogaster
FBal0017295 twe[1] loss of function allele Drosophila melanogaster
FBal0094304 twe[unspecified]   Drosophila melanogaster
FBal0060848 twe[DTD22]   Drosophila melanogaster
FBal0117271 twe[MtnA.T:Ivir\HA1]   Drosophila melanogaster
FBal0083689 twe[T:Ecol\lacZ]   Drosophila melanogaster
FBal0287161 twe[Scer\UAS.ORF]   Drosophila melanogaster
FBal0287162 twe[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0210825 twe[GD11487]   Drosophila melanogaster
FBal0221216 twe[Scer\UAS.P\T.T:Hsap\MYC]   Drosophila melanogaster
FBal0221217 twe[hs.PVS]   Drosophila melanogaster
FBal0233446 twe[KK105261]   Drosophila melanogaster
FBal0274460 twe[NIG.4965R]   Drosophila melanogaster

78 Clones

Secondary Identifier DB identifier
Dmel_dig_013227_0642_2822 FBcl0374612
Dmel_neb_010388_0656_2309 FBcl0374613
DPiM_LD19391 FBcl0741784
AT07169 FBcl0039711
bs39f09 FBcl0056579
EK096837 FBcl0099924
EK260330 FBcl0100606
EK102058 FBcl0100632
EK086361 FBcl0100660
EK191208 FBcl0100666
EK088250 FBcl0100678
EK064239 FBcl0100684
EN03707 FBcl0100935
EK213636 FBcl0101064
EK042806 FBcl0101158
EK044210 FBcl0101170
EK210148 FBcl0101220
LD20092 FBcl0158028
LD04211 FBcl0158029
LD10764 FBcl0158045
LD02913 FBcl0158049
LD19391 FBcl0158051
LD19349 FBcl0158072
LD16907 FBcl0158073
LD23305 FBcl0172385
LD38233 FBcl0172387
RE46230 FBcl0219072
RE25055 FBcl0219100
RE63241 FBcl0219101
RE58745 FBcl0219102

5 Exons

DB identifier Symbol
FBgn0002673:4 twe:4
FBgn0002673:1 twe:1
FBgn0002673:3 twe:3
FBgn0002673:5 twe:5
FBgn0002673:2 twe:2

4 Transcripts

DB identifier Gene
FBtr0080855 twe
FBtr0331446 twe
FBtr0331445 twe
FBtr0331444 twe

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0080855-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0331444-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0331445-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0331446-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080855-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0331444-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0331445-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0331446-3-prime-utr Drosophila melanogaster

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78 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34954 NCBI Entrez Gene identifiers FBgn0002673
60966 BioGRID FBgn0002673

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 93.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 64.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 65.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 78.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 118.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 80.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 38.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 67.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 41.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 74.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 75.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 98.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 102.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 46.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 96.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 57.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 57.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 71.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 91.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 57.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 85.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 70.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 107.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 96.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 93.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1585.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 893.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 208.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 237.0
FBgn0002673 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 181.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0002673:4_FBgn0002673:1 Drosophila melanogaster
intron_FBgn0002673:3_FBgn0002673:1 Drosophila melanogaster
intron_FBgn0002673:5_FBgn0002673:1 Drosophila melanogaster
intron_FBgn0002673:4_FBgn0002673:2 Drosophila melanogaster

14 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage twe none -1.705995349   19067489
Lipid storage twe none -1.184270966   19067489
Cell size and cell-cycle regulation (1) twe none sp   16496002
Cell size and cell-cycle regulation (1) twe Increased G2 DNA content, decreased cytokinesis sp   16496002
Cell size and cell-cycle regulation (2) twe none 1.277   16496002
Cell size and cell-cycle regulation (3) twe none 450   16496002
Cell size and cell-cycle regulation (4) twe none below threshold   16496002
Combinatorial effect with methyl methanesulphonate (2) twe none sp   19543366
Heat nociception (1) twe none 0.9   21074052
Heart development and function (1) twe none 1   20371351
Blood cell homeostasis regulation (1) twe none np   20540764
Blood cell homeostasis regulation (2) twe none np   20540764
Hippo pathway regulation twe none 2.49   23263283
Glycosylation regulation (1) twe none sp   21203496

0 Submissions