Genomics
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17 Alleles
DB identifier | Symbol | Allele Class | Organism |
---|---|---|---|
FBal0240174 | nbs[defl-Delta] | Drosophila melanogaster | |
FBal0009778 | nbs[1] | amorphic allele - genetic evidence | Drosophila melanogaster |
FBal0178690 | nbs[EY15506] | hypomorphic allele - genetic evidence | Drosophila melanogaster |
FBal0258871 | nbs[KK101013] | Drosophila melanogaster | |
FBal0240649 | nbs[Delta180] | Drosophila melanogaster | |
FBal0260677 | nbs[SM9] | Drosophila melanogaster | |
FBal0285732 | nbs[+t5.2] | Drosophila melanogaster | |
FBal0240791 | nbs[Scer\UAS.cOa] | Drosophila melanogaster | |
FBal0009780 | nbs[2] | Drosophila melanogaster | |
FBal0210177 | nbs[GD12399] | Drosophila melanogaster | |
FBal0247440 | nbs[434.T:SV5\V5] | Drosophila melanogaster | |
FBal0247441 | nbs[M1.T:SV5\V5] | Drosophila melanogaster | |
FBal0247442 | nbs[M2.T:SV5\V5] | Drosophila melanogaster | |
FBal0247443 | nbs[M3.T:SV5\V5] | Drosophila melanogaster | |
FBal0247444 | nbs[M4.T:SV5\V5] | Drosophila melanogaster | |
FBal0247445 | nbs[M5.T:SV5\V5] | Drosophila melanogaster | |
FBal0247446 | nbs[M7] | Drosophila melanogaster |
82 Clones
6 Exons
DB identifier | Symbol |
---|---|
FBgn0261530:4 | nbs:4 |
FBgn0261530:2 | nbs:2 |
FBgn0261530:1 | nbs:1 |
FBgn0261530:6 | nbs:6 |
FBgn0261530:3 | nbs:3 |
FBgn0261530:5 | nbs:5 |
6 UTRs
Class | DB identifier |
Organism . Name |
---|---|---|
FivePrimeUTR | FBtr0306039-5-prime-utr | Drosophila melanogaster |
FivePrimeUTR | FBtr0306040-5-prime-utr | Drosophila melanogaster |
FivePrimeUTR | FBtr0306041-5-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0306039-3-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0306040-3-prime-utr | Drosophila melanogaster |
ThreePrimeUTR | FBtr0306041-3-prime-utr | Drosophila melanogaster |
Other
14 Pathways
- Meiosis,
- Recruitment of repair and signaling proteins to double-strand breaks,
- ATM mediated response to DNA double-strand break,
- DNA Damage/Telomere Stress Induced Senescence,
- ATM mediated phosphorylation of repair proteins,
- Cellular Senescence,
- MRN complex relocalizes to nuclear foci,
- Homologous recombination repair of replication-independent double-strand breaks,
- Double-Strand Break Repair,
- DNA Repair,
- Cellular responses to stress,
- Homologous Recombination Repair,
- Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks,
- Meiotic Recombination
2 Cross References
Identifier |
Source . Name |
Subject . Primary Identifier |
---|---|---|
44259 | NCBI Entrez Gene identifiers | FBgn0261530 |
68926 | BioGRID | FBgn0261530 |
10 Data Sets
Name | URL |
---|---|
FlyBase data set for Drosophila melanogaster | |
TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
Drosophila 12 Genomes Consortium homology | |
GenomeRNAi data set | |
TreeFam data set | |
Panther data set | |
IntAct interactions data set | |
BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
GO Annotation from FlyBase | |
FlyBase fasta data set for Drosophila melanogaster |
7 Introns
23 RNAi Results
Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
---|---|---|---|---|---|
Lipid storage | nbs | none | -0.051988402 | 19067489 | |
Lipid storage | nbs | none | 0.037498769 | 19067489 | |
ERK signaling | nbs | ERK activation increased | weak | 17086199 | |
Cell size and cell-cycle regulation (1) | nbs | none | sp | 16496002 | |
Combinatorial effect with methyl methanesulphonate (2) | nbs | none | sp | 19543366 | |
Muscle morphogenesis and function (1) | nbs | none | np | 20220848 | |
Muscle morphogenesis and function (1) | nbs | none | np | 20220848 | |
Heat nociception (1) | nbs | none | -1.17 | 21074052 | |
Heat nociception (1) | nbs | none | -1.17 | 21074052 | |
Heart development and function (1) | nbs | none | 1 | 20371351 | |
Serratia marcescens infection (1) | nbs | none | 0.231343283582089 | 19520911 | |
Notch pathway regulation (4) | nbs | Loss of bristles | 1 | 19363474 | |
Notch pathway regulation (4) | nbs | Colour defects, notum malformation death | sp | 19363474 | |
G2-M DNA damage checkpoint regulation (2) | nbs | Increased histone H3 phosphorylation with doxorubicin | 27.41 | with doxorubicin | 21205937 |
G2-M DNA damage checkpoint regulation (2) | nbs | Increased histone H3 phosphorylation with etoposide | 27.44 | with etoposide | 21205937 |
G2-M DNA damage checkpoint regulation (2) | nbs | none | 24.95 | X-ray exposure | 21205937 |
G2-M DNA damage checkpoint regulation (2) | nbs | none | 9.31 | with bleocin | 21205937 |
Adiposity regulation (1) | nbs | none | -0.319 | 20074523 | |
RTK-Ras-ERK pathway regulation (1) | nbs | none | 0.1 | 0 minutes EGF stimulation | 22028469 |
RTK-Ras-ERK pathway regulation (1) | nbs | none | 0.69 | 10 minutes EGF stimulation | 22028469 |
RTK-Ras-ERK pathway regulation (2) | nbs | none | 0.09 | 30 minutes sSpitz stimulation | 22028469 |
RTK-Ras-ERK pathway regulation (2) | nbs | none | 0.95 | 10 minutes sSpitz stimulation | 22028469 |
Hippo pathway regulation | nbs | none | 1.13 | 23263283 |