Genomics
Gene Ontology Displayer
Homologue Displayer
Mod Mine G Browse Displayer
Overlapping Features Displayer
Regulatory Regions Displayer
17 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0240174 | nbs[defl-Delta] | Drosophila melanogaster | |
| FBal0009778 | nbs[1] | amorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0178690 | nbs[EY15506] | hypomorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0258871 | nbs[KK101013] | Drosophila melanogaster | |
| FBal0240649 | nbs[Delta180] | Drosophila melanogaster | |
| FBal0260677 | nbs[SM9] | Drosophila melanogaster | |
| FBal0285732 | nbs[+t5.2] | Drosophila melanogaster | |
| FBal0240791 | nbs[Scer\UAS.cOa] | Drosophila melanogaster | |
| FBal0009780 | nbs[2] | Drosophila melanogaster | |
| FBal0210177 | nbs[GD12399] | Drosophila melanogaster | |
| FBal0247440 | nbs[434.T:SV5\V5] | Drosophila melanogaster | |
| FBal0247441 | nbs[M1.T:SV5\V5] | Drosophila melanogaster | |
| FBal0247442 | nbs[M2.T:SV5\V5] | Drosophila melanogaster | |
| FBal0247443 | nbs[M3.T:SV5\V5] | Drosophila melanogaster | |
| FBal0247444 | nbs[M4.T:SV5\V5] | Drosophila melanogaster | |
| FBal0247445 | nbs[M5.T:SV5\V5] | Drosophila melanogaster | |
| FBal0247446 | nbs[M7] | Drosophila melanogaster |
82 Clones
6 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0261530:4 | nbs:4 |
| FBgn0261530:2 | nbs:2 |
| FBgn0261530:1 | nbs:1 |
| FBgn0261530:6 | nbs:6 |
| FBgn0261530:3 | nbs:3 |
| FBgn0261530:5 | nbs:5 |
6 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0306039-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0306040-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0306041-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0306039-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0306040-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0306041-3-prime-utr | Drosophila melanogaster |
Other
14 Pathways
- Meiosis,
- MRN complex relocalizes to nuclear foci,
- Homologous recombination repair of replication-independent double-strand breaks,
- Recruitment of repair and signaling proteins to double-strand breaks,
- DNA Repair,
- Double-Strand Break Repair,
- Cellular responses to stress,
- Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks,
- DNA Damage/Telomere Stress Induced Senescence,
- ATM mediated phosphorylation of repair proteins,
- Cellular Senescence,
- Homologous Recombination Repair,
- Meiotic Recombination,
- ATM mediated response to DNA double-strand break
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 44259 | NCBI Entrez Gene identifiers | FBgn0261530 |
| 68926 | BioGRID | FBgn0261530 |
10 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster |
7 Introns
23 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | nbs | none | -0.051988402 | 19067489 | |
| Lipid storage | nbs | none | 0.037498769 | 19067489 | |
| ERK signaling | nbs | ERK activation increased | weak | 17086199 | |
| Cell size and cell-cycle regulation (1) | nbs | none | sp | 16496002 | |
| Combinatorial effect with methyl methanesulphonate (2) | nbs | none | sp | 19543366 | |
| Muscle morphogenesis and function (1) | nbs | none | np | 20220848 | |
| Muscle morphogenesis and function (1) | nbs | none | np | 20220848 | |
| Heat nociception (1) | nbs | none | -1.17 | 21074052 | |
| Heat nociception (1) | nbs | none | -1.17 | 21074052 | |
| Heart development and function (1) | nbs | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | nbs | none | 0.231343283582089 | 19520911 | |
| Notch pathway regulation (4) | nbs | Loss of bristles | 1 | 19363474 | |
| Notch pathway regulation (4) | nbs | Colour defects, notum malformation death | sp | 19363474 | |
| G2-M DNA damage checkpoint regulation (2) | nbs | Increased histone H3 phosphorylation with doxorubicin | 27.41 | with doxorubicin | 21205937 |
| G2-M DNA damage checkpoint regulation (2) | nbs | Increased histone H3 phosphorylation with etoposide | 27.44 | with etoposide | 21205937 |
| G2-M DNA damage checkpoint regulation (2) | nbs | none | 24.95 | X-ray exposure | 21205937 |
| G2-M DNA damage checkpoint regulation (2) | nbs | none | 9.31 | with bleocin | 21205937 |
| Adiposity regulation (1) | nbs | none | -0.319 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | nbs | none | 0.1 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | nbs | none | 0.69 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | nbs | none | 0.09 | 30 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | nbs | none | 0.95 | 10 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | nbs | none | 1.13 | 23263283 |
