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Gene : smt3 D. melanogaster

DB identifier  ? FBgn0264922 Secondary Identifier  ? CG4494
Name  ? smt3 Source  FlyBase
  • synonyms:
  • FBgn0065910,
  • CG4494,
  • dSmt3,
  • lethal (2) SH0182,
  • FBan0004494,
  • DmSUMO-1,
  • FBgn0026170,
  • l(2)SH2 0182,
  • SMT3,
  • Dm0342,
  • FBgn0264922,
  • Small Ubiquitin-like Modifier,
  • l(2)SH0182,
  • SUMO,
  • FBgn0069078,
  • FBgn0025539,
  • DmSmt3,
  • anon-EST:Posey240,
  • FBgn0010577,
  • l(2)04493,
  • SUMO protein

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Regulatory Regions Displayer

30 Alleles

DB identifier Symbol Allele Class Organism
FBal0270277 smt3[ex77]   Drosophila melanogaster
FBal0247032 smt3[Scer\UAS.cMa]   Drosophila melanogaster
FBal0144147 smt3[SH0182]   Drosophila melanogaster
FBal0177756 smt3[c00190]   Drosophila melanogaster
FBal0276748 smt3[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0177757 smt3[c00189]   Drosophila melanogaster
FBal0064718 smt3[k09930]   Drosophila melanogaster
FBal0064719 smt3[k06307]   Drosophila melanogaster
FBal0064720 smt3[k04501]   Drosophila melanogaster
FBal0064721 smt3[k01211]   Drosophila melanogaster
FBal0008063 smt3[04493]   Drosophila melanogaster
FBal0043444 smt3[04841]   Drosophila melanogaster
FBal0043445 smt3[10636]   Drosophila melanogaster
FBal0043446 smt3[k09603]   Drosophila melanogaster
FBal0158632 smt3[dsRNA.cBa]   Drosophila melanogaster
FBal0154565 smt3[unspecified]   Drosophila melanogaster
FBal0240838 smt3[JF02869]   Drosophila melanogaster
FBal0158637 smt3[DeltaGG.MtnA.T:Ivir\HA1]   Drosophila melanogaster
FBal0103544 smt3[Act5C.T:Ivir\HA1]   Drosophila melanogaster
FBal0158636 smt3[Act5C.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0103543 smt3[Act5C.T:Zzzz\His6]   Drosophila melanogaster
FBal0158635 smt3[FL.MtnA.T:Ivir\HA1]   Drosophila melanogaster
FBal0158634 smt3[GG.MtnA.T:Ivir\HA1]   Drosophila melanogaster
FBal0158633 smt3[MtnA.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0263443 smt3[HMS01540]   Drosophila melanogaster
FBal0210631 smt3[GD10521]   Drosophila melanogaster
FBal0231478 smt3[KK101786]   Drosophila melanogaster
FBal0230348 smt3[Scer\UAS.P\T.T:Zzzz\FLAG.T:Zzzz\His6]   Drosophila melanogaster
FBal0230349 smt3[EMS]   Drosophila melanogaster
FBal0280100 smt3[Scer\UAS.cPa]   Drosophila melanogaster

136 Clones

Secondary Identifier DB identifier
UUGC0045 FBcl0001139
UUGC0522 FBcl0006575
AT21522 FBcl0012915
EK204838 FBcl0027860
EK146460 FBcl0028414
EK231802 FBcl0028556
EK227034 FBcl0028584
bs79a08 FBcl0048775
EC30841 FBcl0063159
EC13612 FBcl0063203
EC39405 FBcl0063205
EC22983 FBcl0063233
EC14818 FBcl0063289
EN16634 FBcl0092719
EN05834 FBcl0092725
EN00851 FBcl0092741
EN12847 FBcl0092743
EN11062 FBcl0092753
EN06907 FBcl0092771
EN06738 FBcl0092843
GM01812 FBcl0138959
GM01840 FBcl0139037
GM05543 FBcl0139039
GM10030 FBcl0139089
GM10042 FBcl0139115
GM26067 FBcl0144751
GM26382 FBcl0144755
GM21824 FBcl0144760
LD07775 FBcl0152764
LD21579 FBcl0165412

2 Exons

DB identifier Symbol
FBgn0264922:2 smt3:2
FBgn0264922:1 smt3:1

1 Transcripts

DB identifier Gene
FBtr0079356 smt3

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0079356-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0079356-3-prime-utr Drosophila melanogaster


Cytoscape Network Displayer



2 Cross References

Source . Name

Subject . Primary Identifier
33981 NCBI Entrez Gene identifiers FBgn0264922
60130 BioGRID FBgn0264922

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

1 Introns

DB identifier
Organism . Name
intron_FBgn0264922:2_FBgn0264922:1 Drosophila melanogaster

29 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage smt3 none 4.326860495   19067489
Lipid storage smt3 none 1.019230742   19067489
Chlamydia caviae infection smt3 Decreased Chlamydia caviae infection np   17967059
ERK signaling smt3 ERK activation reduced weak   17086199
Cytokinesis regulation smt3 Binucleate cells with microtubule extensions and decreased viability weak   15547975
Intracellular Listeria monocytogenes infection smt3 Decreased GFP protein expression strong   16020693
L. monocytogenes infection smt3 Fewer bacteria per cell *   16157870
Constitutive protein secretion and Golgi organization (1) smt3 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) smt3 none sp   16496002
Candida albicans phagocytosis (1) smt3 Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) smt3 Decreased Escherichia coli phagocytosis 30   16336044
Candida albicans phagocytosis (3) smt3 Decreased latex beads phagocytosis 28   16336044
Mitosis smt3 Monastral bipolar spindle np   17412918
Mitochondrial biogenesis and function smt3 Decreased mitochondrial citrate synthase activity 0.598   18042644
Combinatorial effect with methyl methanesulphonate (2) smt3 Synthetic lethal with methyl methanesulphonate sp   19543366
Mutant human huntingtin aggregation smt3 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) smt3 Lethal np   20220848
Muscle morphogenesis and function (1) smt3 Lethal np   20220848
Muscle morphogenesis and function (2) smt3 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heart development and function (1) smt3 Embryonic lethal or no offspring 0.5   20371351
Serratia marcescens infection (1) smt3 none 0.148148148148148   19520911
Notch pathway regulation (4) smt3 Completely lethal (pupal) sp   19363474
Adiposity regulation (1) smt3 none -0.815   20074523
RTK-Ras-ERK pathway regulation (1) smt3 none 0.49 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) smt3 none -0.93 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) smt3 none 0.09 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) smt3 Increased ERK phosphorylation after sSpitz and EGF stimulation 1.55 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation smt3 none 0.2   23263283
Huntingtin (Htt) aggregates formation smt3 Decreased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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