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Gene : pnt D. melanogaster

DB identifier  ? FBgn0003118 Secondary Identifier  ? CG17077
Name  ? pointed Source  FlyBase
  • synonyms:
  • DMPOINT1A,
  • l(3)j1B7,
  • ptd,
  • Ets58AB,
  • ETS2,
  • 0998/12,
  • FBan0017077,
  • Pointed,
  • 0608/07,
  • D-Ets-2,
  • Ets protein Pointed P2,
  • CG17077,
  • EK3-2,
  • FBgn0005657,
  • pointed-RC,
  • PNTP1,
  • 3520,
  • unnamed,
  • l(3)s118306,
  • PNTP2,
  • EY3-1,
  • no terminal cell clones-R,
  • Pnt,
  • pnt-P2,
  • FBgn0011309,
  • png,
  • Ets,
  • Ets94F,
  • Pointed2,
  • PNT-P1,
  • FBgn0010925,
  • l(3)07825,
  • PointedP2,
  • FBgn0003118,
  • Pointed-P2,
  • E(E2F)3D,
  • pntegfr,
  • pointed P2,
  • FBgn0004060,
  • POINT,
  • 0123/09,
  • Ets at 58AB,
  • Pointed-P1

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128 Alleles

DB identifier Symbol Allele Class Organism
FBal0220281 pnt[EP3-637]   Drosophila melanogaster
FBal0220282 pnt[EP3-853]   Drosophila melanogaster
FBal0220283 pnt[EP3-1638]   Drosophila melanogaster
FBal0220284 pnt[EP3-1859]   Drosophila melanogaster
FBal0280792 pnt[T:Avic\GFP-SF,T:Zzzz\FLAG,T:Zzzz\PSP.CS,T:Zzzz\TEV.CS,T:Zzzz\BLRP]   Drosophila melanogaster
FBal0269065 pnt[Delta86]   Drosophila melanogaster
FBal0150295 pnt[dsRNA.P1]   Drosophila melanogaster
FBal0150294 pnt[dsRNA.P2]   Drosophila melanogaster
FBal0282991 pnt[MI07710]   Drosophila melanogaster
FBal0178408 pnt[LA00739]   Drosophila melanogaster
FBal0178402 pnt[d07131]   Drosophila melanogaster
FBal0178401 pnt[d07175]   Drosophila melanogaster
FBal0178405 pnt[d00286]   Drosophila melanogaster
FBal0035442 pnt[1277] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0260328 pnt[MI02427]   Drosophila melanogaster
FBal0178400 pnt[d07883]   Drosophila melanogaster
FBal0035449 pnt[03520]   Drosophila melanogaster
FBal0178403 pnt[d02978]   Drosophila melanogaster
FBal0178404 pnt[d01415]   Drosophila melanogaster
FBal0178406 pnt[d00078]   Drosophila melanogaster
FBal0032469 pnt[rM254] amorphic allele - genetic evidence Drosophila melanogaster
FBal0178399 pnt[f01588]   Drosophila melanogaster
FBal0248866 pnt[VDRC.cUa]   Drosophila melanogaster
FBal0178407 pnt[c00584]   Drosophila melanogaster
FBal0196823 pnt[198]   Drosophila melanogaster
FBal0196824 pnt[1318]   Drosophila melanogaster
FBal0035450 pnt[03680]   Drosophila melanogaster
FBal0035452 pnt[05484]   Drosophila melanogaster
FBal0158798 pnt[EY03254]   Drosophila melanogaster
FBal0009603 pnt[07825]   Drosophila melanogaster

88 Clones

Secondary Identifier DB identifier
SD26148 FBcl0000284
EN12741 FBcl0099277
EN00761 FBcl0099281
EN17013 FBcl0099285
EN13323 FBcl0099291
EN14353 FBcl0099293
EN09459 FBcl0099295
EK271863 FBcl0121498
EK200709 FBcl0121510
EK272321 FBcl0121518
EK170318 FBcl0121524
EK190150 FBcl0121534
EK210761 FBcl0121598
EK252250 FBcl0121634
EK235525 FBcl0121638
EK115818 FBcl0121642
EK048464 FBcl0121716
EK307555 FBcl0121722
GH05922 FBcl0122153
GH06240 FBcl0122933
LD08639 FBcl0158222
RE52147 FBcl0219296
RE74191 FBcl0219932
RE64372 FBcl0220112
RE18543 FBcl0220322
RE14061 FBcl0223822
RH14307 FBcl0260291
RH32337 FBcl0260483
RH61117 FBcl0260695
RH13217 FBcl0260750

13 Exons

DB identifier Symbol
FBgn0003118:10 pnt:10
FBgn0003118:13 pnt:13
FBgn0003118:12 pnt:12
FBgn0003118:11 pnt:11
FBgn0003118:9 pnt:9
FBgn0003118:8 pnt:8
FBgn0003118:7 pnt:7
FBgn0003118:4 pnt:4
FBgn0003118:3 pnt:3
FBgn0003118:1 pnt:1
FBgn0003118:6 pnt:6
FBgn0003118:2 pnt:2
FBgn0003118:5 pnt:5

4 Transcripts

DB identifier Gene
FBtr0089716 pnt
FBtr0089717 pnt
FBtr0334554 pnt
FBtr0089715 pnt

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0089717-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0089715-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0089716-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334554-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0089717-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0089715-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0089716-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334554-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42757 NCBI Entrez Gene identifiers FBgn0003118
67700 BioGRID FBgn0003118

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3745.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2516.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2082.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2225.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2748.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 4969.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3674.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 4996.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 10538.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2725.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 4317.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 3452.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 4470.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2307.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 5550.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 4027.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 7451.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2645.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 3472.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2429.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2671.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3748.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2961.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 7896.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2043.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 292.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 557.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1619.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1357.0
FBgn0003118 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1326.0

12 Introns

DB identifier
Organism . Name
intron_FBgn0003118:13_FBgn0003118:12 Drosophila melanogaster
intron_FBgn0003118:12_FBgn0003118:11 Drosophila melanogaster
intron_FBgn0003118:11_FBgn0003118:9 Drosophila melanogaster
intron_FBgn0003118:9_FBgn0003118:8 Drosophila melanogaster
intron_FBgn0003118:8_FBgn0003118:7 Drosophila melanogaster
intron_FBgn0003118:7_FBgn0003118:4 Drosophila melanogaster
intron_FBgn0003118:4_FBgn0003118:3 Drosophila melanogaster
intron_FBgn0003118:3_FBgn0003118:1 Drosophila melanogaster
intron_FBgn0003118:6_FBgn0003118:4 Drosophila melanogaster
intron_FBgn0003118:3_FBgn0003118:2 Drosophila melanogaster
intron_FBgn0003118:10_FBgn0003118:9 Drosophila melanogaster
intron_FBgn0003118:5_FBgn0003118:4 Drosophila melanogaster

28 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage pnt Decreased lipid droplet area -3.987984757   19067489
Lipid storage pnt Decreased lipid droplet area -2.146386614   19067489
Lipid storage pnt none 2.044538318   19067489
Lipid storage pnt none 1.87438281   19067489
Neural outgrowth pnt Short axons np   18604272
Wnt signaling pnt Increased Wnt reporter activity 5.9   15817814
Hedgehog signaling pnt Increased Hedgehog reporter activity 3.2   16311596
Constitutive protein secretion and Golgi organization (1) pnt Decreased horseradish peroxidase protein expression sp   16452979
Candida albicans phagocytosis (1) pnt Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) pnt Decreased Escherichia coli phagocytosis 38   16336044
Candida albicans phagocytosis (3) pnt none 45   16336044
Dendrite pattern formation pnt none np   16547170
Mutant human huntingtin aggregation pnt Decreased mutant human huntingtin aggregation <= -2   19789644
Heat nociception (1) pnt none -1.17   21074052
Heart development and function (1) pnt none 1   20371351
Serratia marcescens infection (1) pnt none -2.03030303030303   19520911
Notch pathway regulation (4) pnt Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) pnt Completely lethal (pupal) sp   19363474
PGN-induced dJNK phosphorylation pnt Increased P-JNK protein expression with PGN 5.32 15 min PGN induction 19893628
Hh pathway regulation pnt Upregulation of Hh pathway 0.615846685743114   17903264
Hh pathway regulation pnt Upregulation of Hh pathway 0.883837151694026   17903264
Notch pathway regulation (1) pnt Upregulation of Notch pathway np   20493818
Adiposity regulation (1) pnt none -0.276   20074523
RTK-Ras-ERK pathway regulation (2) pnt none 1.1 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) pnt Increased ERK phosphorylation after sSpitz and EGF stimulation 2.8 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation pnt Downregulation of Hippo pathway 6.42   23263283
Srp/Lz-induced transcriptional activation pnt Increased Srp/Lz-induced transcription 7.38   20368357
Immune deficiency pathway regulation pnt Upregulation of IMD pathway after E.coli stimulation 7.21   21297578

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