Genomics
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56 Alleles
625 Clones
16 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0004907:3 | 14-3-3zeta:3 |
| FBgn0004907:7 | 14-3-3zeta:7 |
| FBgn0004907:8 | 14-3-3zeta:8 |
| FBgn0004907:9 | 14-3-3zeta:9 |
| FBgn0004907:10 | 14-3-3zeta:10 |
| FBgn0004907:11 | 14-3-3zeta:11 |
| FBgn0004907:16 | 14-3-3zeta:16 |
| FBgn0004907:2 | 14-3-3zeta:2 |
| FBgn0004907:12 | 14-3-3zeta:12 |
| FBgn0004907:1 | 14-3-3zeta:1 |
| FBgn0004907:13 | 14-3-3zeta:13 |
| FBgn0004907:15 | 14-3-3zeta:15 |
| FBgn0004907:4 | 14-3-3zeta:4 |
| FBgn0004907:14 | 14-3-3zeta:14 |
| FBgn0004907:5 | 14-3-3zeta:5 |
| FBgn0004907:6 | 14-3-3zeta:6 |
24 UTRs
Other
73 Pathways
- Frs2-mediated activation,
- IRS-related events triggered by IGF1R,
- ARMS-mediated activation,
- Downstream signaling of activated FGFR,
- SHC1 events in ERBB4 signaling,
- Signalling to RAS,
- Signaling by FGFR in disease,
- Insulin signaling pathway,
- SHC1 events in ERBB2 signaling,
- Signaling by NGF,
- Destabilization of mRNA by KSRP,
- Signaling by ERBB2,
- IRS-related events,
- Innate Immune System,
- Signaling by Hippo,
- SHC-mediated signalling,
- Cytokine Signaling in Immune system,
- GP1b-IX-V activation signalling,
- GRB2 events in EGFR signaling,
- Transcription,
- Insulin receptor recycling,
- Insulin receptor signalling cascade,
- MEK activation,
- mRNA Processing,
- Signaling by EGFR,
- FRS2-mediated cascade,
- NGF signalling via TRKA from the plasma membrane,
- Signaling by SCF-KIT,
- Signaling by GPCR,
- SOS-mediated signalling,
- Immune System,
- Gastrin-CREB signalling pathway via PKC and MAPK,
- Signalling to p38 via RIT and RIN,
- Platelet activation, signaling and aggregation,
- FCERI mediated MAPK activation,
- DAP12 interactions,
- Regulation of mRNA Stability by Proteins that Bind AU-rich Elements,
- Metabolism of mRNA,
- Prolonged ERK activation events,
- Developmental Biology,
- DAP12 signaling,
- Signaling Pathways,
- Destabilization of mRNA by Butyrate Response Factor 1 (BRF1),
- Metabolism of RNA,
- SHC1 events in EGFR signaling,
- GRB2 events in ERBB2 signaling,
- Gene Expression,
- Signaling by ERBB4,
- Axon guidance,
- SHC-related events triggered by IGF1R,
- IGF1R signaling cascade,
- RAF/MAP kinase cascade,
- RAF activation,
- Hemostasis,
- Fc epsilon receptor (FCERI) signaling,
- RAF phosphorylates MEK,
- Signaling by EGFR in Cancer,
- Signaling by Leptin,
- SHC-related events,
- Adaptive Immune System,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- Downstream signal transduction,
- Signaling by Interleukins,
- Disease,
- Interleukin-2 signaling,
- Signaling by FGFR,
- IRS-mediated signalling,
- Signalling to ERKs,
- DINR-mediated activation,
- Rap1 signalling,
- NCAM signaling for neurite out-growth,
- Signaling by PDGF,
- Insulin receptor mediated signaling
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 36059 | NCBI Entrez Gene identifiers | FBgn0004907 |
| 61887 | BioGRID | FBgn0004907 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
19 Introns
21 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | 14-3-3zeta | none | -1.818643279 | 19067489 | |
| Lipid storage | 14-3-3zeta | none | -0.018250916 | 19067489 | |
| ERK signaling | 14-3-3zeta | ERK activation reduced | strong | 17086199 | |
| Cell size and cell-cycle regulation (1) | 14-3-3zeta | none | sp | 16496002 | |
| Combinatorial effect with methyl methanesulphonate (2) | 14-3-3zeta | none | sp | 19543366 | |
| Heat nociception (1) | 14-3-3zeta | none | 0.81 | 21074052 | |
| Heart development and function (1) | 14-3-3zeta | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | 14-3-3zeta | none | -0.239130434782608 | 19520911 | |
| Notch pathway regulation (4) | 14-3-3zeta | none | 0 | 19363474 | |
| Notch pathway regulation (1) | 14-3-3zeta | Upregulation of Notch pathway | np | 20493818 | |
| Notch pathway regulation (2) | 14-3-3zeta | none | np | en-GAL4 | 20493818 |
| Notch pathway regulation (2) | 14-3-3zeta | none | np | en-GAL4 | 20493818 |
| Notch pathway regulation (3) | 14-3-3zeta | Upregulation of Notch pathway | np | 20493818 | |
| Adiposity regulation (1) | 14-3-3zeta | none | 0.57 | 20074523 | |
| Vaccinia virus infection | 14-3-3zeta | none | sp | 20585561 | |
| RTK-Ras-ERK pathway regulation (1) | 14-3-3zeta | none | 0.5 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | 14-3-3zeta | none | 0.14 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | 14-3-3zeta | none | -0.46 | 30 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | 14-3-3zeta | none | -0.14 | 10 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | 14-3-3zeta | none | 0.62 | 23263283 | |
| Glycosylation regulation (1) | 14-3-3zeta | none | sp | 21203496 |
